细胞核内iASPP调控Nrf2的分子机制及其影响化疗敏感性的研究

31871389
2018
C0705.细胞衰老、死亡及自噬
胡颖
面上项目
教授
哈尔滨工业大学
60万元
信号通路;细胞凋亡诱导剂;化疗;p53凋亡刺激蛋白抑制因子;活性氧
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca 2+ homeostasis and control tumor growth and drug resistance 期刊论文 Shanliang Zheng;Dong Zhao;Guixue Hou;Song Zhao;Wenxin Zhang;Xingwen Wang;Li Li;Liang Lin;Tie-Shan Tang;Ying Hu
2 A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers 期刊论文 Zhao Kunming;Wang Xingwen;Xue Xuting;Li Li;Hu Ying
3 iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers. 期刊论文 Zheng S;Wang X;Liu H;Zhao D;Lin Q;Jiang Q;Li Li;Ying Hu
4 Blocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization 期刊论文 Hanxin Liu;Dong Zhao;Huayi Li;Wenxin Zhang;Qingyu Lin;Xingwen Wang;Shanliang Zheng;Lei Zhang;Li Li;Shaoshan Hu;Ying Hu
5 Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications 期刊论文 Shanliang Zheng;Xiuchao Wang;Dong Zhao;Hao Liu;Ying Hu
6 Microbiome harbored within tumors: a new chance to revisit our understanding of cancer pathogenesis and treatment 期刊论文 Zhao Kunming;Hu Ying
7 A lncRNA coordinates with Ezh2 to inhibit HIF-1α transcription and suppress cancer cell adaption to hypoxia 期刊论文 Xingwen Wang;Yudong Wang;Li Li;Xuting Xue;Hui Xie;Huaxing Shi;Ying Hu
8 lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma 期刊论文 Xingwen Wang;Shanliang Zheng;Fan Yang;Wenxin Zhang;Dong Zhao;Xuting Xue;Qingyu Lin;Yunfei He;Guohong Hu;Ying Hu
9 A previously identified apoptosis inhibitor iASPP confers resistance to chemotherapeutic drugs by suppressing senescence in cancer cells 期刊论文 Huayi Li;Wenxin Zhang;Kunming Zhao;Dong Zhao;Shanliang Zheng;Ying Hu
10 iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation 期刊论文 Dong Zhao;Shanliang Zheng;Xingwen Wang;Hao Liu;Kunming Zhao;Li Li;Ying Hu
11 Interplay of long non-coding RNAs and HIF-1α: A new dimension to understanding hypoxia-regulated tumor growth and metastasis 期刊论文 Xingwen Wang;Dong Zhao;Hui Xie;Ying Hu
12 lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization 期刊论文 Kunming Zhao;Xingwen Wang;Dong Zhao;Qingyu Lin;Yi Zhang;Ying Hu
13 A novel LncRNA HITT forms a regulatory loop with HIF-1α to modulate angiogenesis and tumor growth 期刊论文 Xingwen Wang;Li Li;Kunming Zhao;Qingyu Lin;Huayi Li;Xuting Xue;Wenjie Ge;Hongjuan He;Dong Liu;Hui Xie;Qiong Wu;Ying Hu
14 Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-kappa B 期刊论文 Ge Wenjie;Wang Yudong;Zheng Shanliang;Zhao Dong;Wang Xingwen;Zhang Xiaoshi;Hu Ying
15 Identification of lncRNA-Protein Interactions by CLIP and RNA Pull-Down Assays. 期刊论文 Kunming Zhao;Xingwen Wang;Ying Hu
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