基于新一代测序数据识别影响重症肌无力药物反应的miRNA多态及机制研究
81571166
2015
H0907.神经系统免疫异常及相关疾病
王丽华
面上项目
教授
哈尔滨医科大学
57万元
药物反应;新一代测序数据;miRNA多态;重症肌无力
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Autophagy-related gene expression is an independent prognostic indicator of glioma | 期刊论文 | Zhang Huixue;Lu Xiaoyan;Wang Ning;Wang Jianjian;Cao Yuze;Wang Tianfeng;Zhou Xueling;Jiao Yang;Yang Lei;Wang Xiaokun;Cong Lin;Li Jianlong;Li Jie;Ma He Ping;Pan Yonghui;Ning Shangwei;Wang Lihua |
| 2 | The long noncoding RNA MALAT-1 functions as a competing endogenous RNA to regulate MSL2 expression by sponging miR-338-3p in myasthenia gravis | 期刊论文 | Kong Xiaotong;Wang Jianjian;Cao Yuze;Zhang Huixue;Lu Xiaoyu;Wang Yu;Bo Chunrui;Wang Tianfeng;Li Shuang;Tian Kuo;Liu Zhaojun;Wang Lihua |
| 3 | 识别miRNA调控重症肌无力风险通路的“开关”多态研究 | 奖励 | 王丽华;田庆华;张荟雪;曹宇泽;王健健 |
| 4 | 重症肌无力风险miRNA多态位点识别miRNA调控通路研究 | 奖励 | 王丽华;刘昭君;张荟雪;王健健;曹宇泽 |
| 5 | Building the drug-GO function network to screen significant candidate drugs for myasthenia gravis | 期刊论文 | Li Shuang;Cao Yuze;Li Lei;Zhang Huixue;Lu Xiaoyu;Bo Chunrui;Kong Xiaotong;Liu Zhaojun;Chen Lixia;Liu Peifang;Jiao Yang;Wang Jianjian;Ning Shangwei;Wang Lihua |
| 6 | Global pathway view analysis of microRNA clusters in myasthenia gravis | 期刊论文 | Bo Chunrui;Wang Jianjian;Zhang Huixue;Cao Yuze;Lu Xiaoyu;Wang Tianfeng;Wang Yu;Li Shuang;Kong Xiaotong;Sun Xuesong;Liu Zhaojun;Ning Shangwei;Wang Lihua |
| 7 | Association of C-reactive protein and vitamin D deficiency with cardiovascular disease: A nationwide cross-sectional study from National Health and Nutrition Examination Survey 2007 to 2008 | 期刊论文 | Li Qian;Dai Zhenguo;Cao Yuze;Wang Lihua |
| 8 | ceRNA在神经系统肿瘤与免疫病中的研究进展 | 期刊论文 | 王天风;王丽华;王健健;陆小燕 |
| 9 | MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy | 期刊论文 | Wang Ning;Yang Lei;Zhang Huixue;Lu Xiaoyu;Wang Jianjian;Cao Yuze;Chen Lixia;Wang Xiaokun;Cong Lin;Li Jie;Wang Na;Liu Zhaojun;Wang Lihua |
| 10 | Characterization of Transcriptome Transition Associates Long Noncoding RNAs with Glioma Progression | 期刊论文 | Lin Xiaoyu;Jiang Tiantongfei;Bai Jing;Li Junyi;Wang Tianshi;Xiao Jun;Tian Yi;Jin Xiyun;Shao Tingting;Xu Juan;Chen Lingchao;Wang Lihua;Li Yongsheng |
| 11 | NSDNA:A manuallycurated database of experimentally supported ncRNAs associated with nervoussystem diseases | 期刊论文 | Wang Jianjian;Cao Yuze;Zhang Huixue;Wang Tianfeng;Lu Xiaoyu;Lu Xiaoyan;Kong Xiaotong;Liu Zhaojun;Wang Ning;Zhang Shuai;Ma Heping;Ning Shangwei;Wang Lihua |
| 12 | MicroRNAs and nervous system diseases: network insights and computational challenges | 期刊论文 | Wang JJ;Cao YZ;Lu XY;Wang TF;Li S;Kong XT;Bo CR;Li J;Wang XL;Ma HP;Li L;Zhang HX;Ning SW;Wang LH |
| 13 | Construction of an miRNA-regulated drug-pathway network reveals drugrepurposing candidates for myasthenia gravis | 期刊论文 | Yuze Cao;Xiaoyan Lu;Jianjian Wang;Huixue Zhang;Zhaojun Liu;Si Xu;Tianfeng Wang;Shangwei Ning;Bo Xiao;Lihua Wang |
| 14 | 长链非编码RNA在神经系统疾病中的功能及研究进展 | 期刊论文 | 周雪灵;王健健;张荟雪;陈丽霞;王丽华 |
| 15 | Caspase-1 inhibition mediates neuroprotection in experimental stroke by polarizing M2 microglia/macrophage and suppressing NF-kappa B activation | 期刊论文 | Li Qian;Dai Zhenguo;Cao Yuze;Wang Lihua |
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