细胞自噬作用角色的转变在肝癌索拉非尼耐药机制中的研究

81401975
2014
H1815.肿瘤靶向治疗
翟博
青年科学基金项目
主任医师
哈尔滨医科大学
23万元
信号通路;C09_肝和肝内胆管肿瘤;自噬;索拉菲尼
2015-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Dual inhibition of Akt and c-Met as a second-line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells 期刊论文 Han Peng;Li Hali;Jiang Xian;Zhai Bo;Tan Gang;Zhao Dali;Qiao Haiquan;Liu Bing;Jiang Hongchi;Sun Xueying
2 PI3K/AKt信号通路与肝癌对索拉菲尼耐药机制的研究进展 期刊论文 董杰杰;翟博;许军
3 Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress. 期刊论文 Zhai Bo;Hu Fengli;Yan Haijiang;Zhao Dali;Jin Xin;Fang Taishi;Pan Shangha;Sun Xueying;Xu Lishan
4 Arsenic trioxide potentiates the anti-cancer activities of sorafenib against hepatocellular carcinoma by inhibiting Akt activation. 期刊论文 Zhai Bo;Jiang Xian;He Changjun;Zhao Dali;Ma Lixin;Xu Lishan;Jiang Hongchi;Sun Xueying
5 Applying negative pressure wound therapy in associating liver partition and portal vein ligation for staged hepatectomy: A case report 期刊论文 Zhai Bo;Jin Xin;Wang Rui;Fang Taishi;Qu Jing;Wang Ying;Liu Ming;Xu Lishan
6 MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway. 期刊论文 He Changjun;Dong Xuesong;Zhai Bo;Jiang Xian;Dong Deli;Li Baoxin;Jiang Hongchi;Xu Shidong;Sun Xueying
7 Activation of phosphatidylinositol 3-kinase/AKT/snail signaling pathway contributes to epithelial-mesenchymal transition-induced multi-drug resistance to sorafenib in hepatocellular carcinoma cells 期刊论文 Dong Jiejie;Zhai Bo;Sun Weihua;Hu Fengli;Cheng Hao;Xu Jun
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