海洋来源新骨架生物碱HDN636靶向Hsp90抗肿瘤作用机制的研究

41676127
2016
D0604.生物海洋学与海洋生物资源
刘明
面上项目
教授
中国海洋大学
69万元
新结构骨架;抗肿瘤;生物活性;海洋微生物资源;热休克蛋白90
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Fungal mycotoxin penisuloxazin A, a novel C-terminal Hsp90 inhibitor and characteristics of its analogues on Hsp90 function related to binding sites 期刊论文 Jiajia Dai;Meilin Zhu;Xin Qi;Yanjuan Wang;Huilin Li;Shuai Tang;Qiang Wang;Ao Chen;Ming Liu;Qianqun Gu;Dehai Li;Jing Li
2 Inducing Secondary Metabolite Production by Combined Culture of Talaromyces aculeatus and Penicillium variabile 期刊论文 Zhang Zhenzhen;He Xueqian;Zhang Guojian;Che Qian;Zhu Tianjiao;Gu Qianqun;Li Dehai
3 AS1041, a Novel Synthesized Derivative of Marine Natural Compound Aspergiolide A, Arrests Cell Cycle, Induces Apoptosis, and Inhibits ERK Activation in K562 Cells 期刊论文 Yuan Fengli;Qiao Liang;Chen Yinghan;Qi Xin;Liu Yankai;Li Dehai;Gu Qianqun;Li Jing;Liu Ming
4 Marine Streptomyces sp derived antimycin analogues suppress HeLa cells via depletion HPV E6/E7 mediated by ROS-dependent ubiquitin-proteasome system 期刊论文 Zhang Weiyi;Che Qian;Tan Hongsheng;Qi Xin;Li Jing;Li Dehai;Gu Qianqun;Zhu Tianjiao;Liu Ming
5 Prenylflavonoid Isoxanthohumol Sensitizes MCF-7/ADR Cells to Doxorubicin Cytotoxicity via Acting as a Substrate of ABCB1 期刊论文 Liu Ming;Zhang Weiyi;Zhang Wei;Zhou Xin;Li Ming;Miao Jinlai
6 Penicisulfuranols A-F, Alkaloids from the Mangrove Endophytic Fungus Penicillium janthinellum HDN13-309 期刊论文 Zhu Meilin;Zhang Xiaomin;Feng Huimin;Dai Jiajia;Li Jing;Che Qian;Guil Qianqun;Zhu Tianjiao;Li Dehai
7 Progress of Bromophenols in Marine Algae from 2011 to 2020: Structure, Bioactivities, and Applications 期刊论文 Dong Hui;Dong Songtao;Hansen Poul Erik;Stagos Dimitrios;Lin Xiukun;Liu Ming
8 Chetracins E and F, cytotoxic epipolythiodioxopiperazines from the marine-derived fungus Acrostalagmus luteoalbus HDN13-530 期刊论文 Yu Guihong;Wang Yanjuan;Yu Rilei;Feng Yanyan;Wang Lu;Che Qian;Gu Qianqun;Li Dehai;Li Jing;Zhu Tianjiao
9 Saroclides A and B, Cyclic Depsipeptides from the Mangrove-Derived Fungus Sarocladium kiliense HDN11-112 期刊论文 Guo Wenqiang;Wang Shuai;Li Na;Li Feng;Zhu Tianjiao;Gu Qianqun;Guo Peng;Li Dehai
10 Teratogenic jervine increases the activity of doxorubicin in MCF-7/ADR cells by inhibiting ABCB1 期刊论文 Liu Ming;Lu Xuxiu;Zhang Jinman;Zhao Xingzeng;Zhang Wei;Lin Xiukun
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