基于癌基因组突变谱解析癌相关生物通路间的协同机制

81071646
2010
H1801.肿瘤病因
郭政
面上项目
教授
哈尔滨医科大学
32万元
遗传异质性;基因突变;功能协同;功能通路;癌基因组
2011-01-01到2013-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Analyzing the Co-Disruption of Functions Related to Lung Adenocarcinoma Based on Gene Ontology 期刊论文 WANG Jing, ZHOU Xianxiao, ZHU Jing, ZHAO Wenyuan,|WANG Jing, ZHOU Xianxiao, ZHU Jing, ZHAO Wenyuan,|
2 GO-function: deriving biologically relevant functions from statistically significant functions 期刊论文 Jing Wang,Xianxiao Zhou,Jing Zhu,Yunyan Gu,Wenyua|Jing Wang,Xianxiao Zhou,Jing Zhu,Yunyan Gu,Wenyua|
3 Analysis of pathway mutation profiles highlights collaboration between cancer-associated superpathways 期刊论文 Yunyan Gu, Wenyuan Zhao, Jiguang Xia, Yuannv Zhan|Yunyan Gu, Wenyuan Zhao, Jiguang Xia, Yuannv Zhan|
4 Evaluating the Consistency of Differential Expression of MicroRNA Detected in Human Cancers 期刊论文 Xue Gong, Ruihong Wu, Hongwei Wang, Xinwu Guo, Do|
5 Functional Comparison between Genes Dysregulated in Ulcerative Colitis and Colorectal Carcinoma 期刊论文 Wenyuan Zhao, Lishuang Qi, Yao Qin, Hongwei|Wenyuan Zhao, Lishuang Qi, Yao Qin, Hongwei|
6 Multi-level reproducibility of signature hubs in human interactome for breast cancer metastasis 期刊论文 Chen Yao , Hongdong Li , Chenggui Zhou , Lin Zhan|
7 Reproducible Cancer Biomarker Discovery in SELDI-TOF MS Using Different Pre-Processing Algorithms 期刊论文 Jinfeng Zou, Guini Hong, Xinwu Guo, Lin Zhang, Ch|Jinfeng Zou, Guini Hong, Xinwu Guo, Lin Zhang, Ch|
8 Identifying Driver Genes of Breast Cancer by Integrated Analysis of Methylation and Expression Data in Paired Disease-Normal Samples of Patients 期刊论文 Xiaopei Shen,Shan Li, Zheng Guo|Xiaopei Shen,Shan Li, Zheng Guo|
9 Identifying Disease-Associated Functions Based on Weak Signals of Differential Expressions of Genes 期刊论文 ZOU Jinfeng, HAO Chunxiang, HE Lang, GUO Zheng|ZOU Jinfeng, HAO Chunxiang, HE Lang, GUO Zheng|
10 Genes Dysregulated to Different Extent or Oppositely in Estrogen Receptor-Positive and Estrogen Receptor-Negative Breast Cancers 期刊论文 Xianxiao Zhou, Tongwei Shi, Bailiang Li , Yuannv|Xianxiao Zhou, Tongwei Shi, Bailiang Li , Yuannv|
11 Comparison of different normalization assumptions for analyses of DNA methylation data from the cancer genome 期刊论文 Dong Wang, Yuannv Zhang, Yan Huang, Pengfei Li|Dong Wang, Yuannv Zhang, Yan Huang, Pengfei Li|
12 Extensive up-regulation of gene expression in cancer: the normalised use of microarray data 期刊论文 Dong Wang, Lixin Cheng, Yuannv Zhang, Ruihong|
13 An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes 期刊论文 Xiaopei Shen, Shan Li, Lin Zhang, Hongdong Li,|Xiaopei Shen, Shan Li, Lin Zhang, Hongdong Li,|
14 Pitfalls in Experimental Designs for Characterizing the Transcriptional, Methylational and Copy Number Changes of Oncogenes and Tumor Suppressor Genes 期刊论文 Yuannv Zhang, Jiguang Xia, Yujing Zhang, Yao Q|Yuannv Zhang, Jiguang Xia, Yujing Zhang, Yao Q|
15 Extensive increase of microarray signals in cancers calls for novel normalization assumptions 期刊论文 Wang D, Cheng L, Wang M, Wu R, Li P, Li B, Zhang|Wang D, Cheng L, Wang M, Wu R, Li P, Li B, Zhang|
16 Extracting a few functionally reproducible biomarkers to build robust subnetwork-based classifiers for the diagnosis of cancer. 期刊论文 Zhang L, Li S, Hao C, Hong G, Zou J, Zhang Y, Li|Zhang L, Li S, Hao C, Hong G, Zou J, Zhang Y, Li|
17 Revealing weak differential gene expressions and their reproducible functions associated with breast cancer metastasis 期刊论文 Jinfeng Zou, Chunxiang Hao, Guini Hong, Junjie Zh|Jinfeng Zou, Chunxiang Hao, Guini Hong, Junjie Zh|
18 Separate enrichment analysis of pathways for up- and downregulated genes 期刊论文 Guini Hong , Wenjing Zhang , Hongdong Li , Xiao|
19 Distinct Functional Patterns of Gene Promoter Hypomethylation and Hypermethylation in Cancer Genomes 期刊论文 Xiaopei Shen, Zheng He, Hongdong Li, Chen Yao,|Xiaopei Shen, Zheng He, Hongdong Li, Chen Yao,|
20 Reproducibility and Concordance of Differential DNA Methylation and Gene Expression in Cancer 期刊论文 Chen Yao, Hongdong Li, Xiaopei Shen, Zheng He,|Chen Yao, Hongdong Li, Xiaopei Shen, Zheng He,|
21 Network analysis of genomic alteration profiles reveals co-altered functional modules and driver genes for glioblastoma 期刊论文 Yunyan Gu, Hongwei Wang, Yao Qin, Yujing Zh|Yunyan Gu, Hongwei Wang, Yao Qin, Yujing Zh|
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