【30973474】探索缺氧诱导因子新通路提高肝癌疗效的研究国家自然基金项目

探索缺氧诱导因子新通路提高肝癌疗效的研究

项目批准号： 30973474

批准年份： 2009

学科分类： H1819.肿瘤生物治疗

项目负责人：孙学英

资助类别：面上项目

负责人职称：教授

依托单位：哈尔滨医科大学

资助金额： 31万元

关键词：肝癌;缺氧诱导因子-2alpha亚单位;肿瘤新生血管生成;缺氧诱导反应

起止时间： 2010-01-01到2012-12-31

中英文摘要
结题摘要
结题报告
项目成果
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序号	标题	类型	作者
1	Bilirubin protects grafts against nonspecific inflammation-induced injury in syngeneic intraportal islet transplantation	期刊论文	Zhu, Huaqiang\|Wang, Jizhou\|Jiang, Hongchi\|Ma, Yong\|Pan, Shangha\|Reddy, Shiva\|Sun, Xueying\|
2	Matrine Attenuates Endotoxin-Induced Acute Liver Injury After Hepatic Ischemia/Reperfusion in Rats	期刊论文	Zhang F\|Wang X\|Tong L\|Qiao H\|Li X\|You L\|Jiang H\|Sun X\|
3	Hepatic Overexpression of Heme Oxygenase-1 Improves Liver Allograft Survival by Expanding T Regulatory Cells	期刊论文	Sun L\|Shi T\|Qiao H\|Jiang X\|Jiang H\|Krissansen GW\|Sun X\|
4	Genistein synergizes with arsenic trioxide to suppress human hepatocellular carcinoma	期刊论文	Jiang H\|Ma Y\|Chen X\|Pan S\|Sun B\|Krissansen GW\|Sun X\|
5	Enhanced induction of heme oxygenase-1 suppresses thrombus formation and affects the protein C system in sepsis	期刊论文	Fei, Dongsheng\|Jiang, Hongchi\|Krissansen, Geoffrey W.\|Zhao, Mingyan\|Sun, Xueying\|Meng, Xianglin\|Zhao, Mingran\|Kang, Kai\|Tan, Gang\|Pan, Shangha\|Luo, Yunpeng\|Liu, Wen\|Nan, Chuanchuan\|
6	Hydrogen sulfide attenuates carbon tetrachloride-induced hepatotoxicity, liver cirrhosis and portal hypertension in rats	期刊论文	Tan G\|Jiang H\|Sun X\|Pan S\|Li J\|Dong X\|Kang K\|Zhao M\|Qiao H\|Jiang X\|Kanwar RJ\|
7	Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer	期刊论文	Ma, Lixin\|Qiao, Haiquan\|He, Changjun\|Yang, Qian\|Cheung, Chun Hei Antonio\|Kanwar, Jagat R.\|Sun, Xueying\|
8	Secretory clusterin contributes to oxaliplatin resistance by activating Akt pathway in hepatocellular carcinoma	期刊论文	Xiu P\|Jiang H\|Li J\|Xue Ying SUN\|Dong X-S\|Dong X-F\|Xu Z\|Zhu H\|Liu F\|Wei Z\|Zhai B\|Kanwar JR\|
9	Synergistic effects of ABT-737 and arsenic trioxide in inducing apoptosis of gastric cancer cells	期刊论文	Sun X-P\|He C\|Qiao H\|Jiang X\|Jiang H\|Xue Ying SUN\|
10	The Inhibitory Role of B7-H4 in Antitumor Immunity:Association with Cancer Progression and Survival	期刊论文	He C\|Qiao H\|Jiang H\|Xue Ying SUN\|
11	Matrine Inhibits Proliferation and Induces Apoptosis of Pancreatic Cancer Cells in Vitro and in Vivo	期刊论文	Liu, Tianyou\|Song, Yon\|Chen, Hua\|Pan, Shangha\|Sun, Xueying\|
12	Antisense HIF-1 alpha prevents acquired tumour resistance to angiostatin gene therapy	期刊论文	Sun X\|Vale M\|Jiang X\|Gupta R\|Krissansen GW\|
13	Overexpression of von Hippel-Lindau enhances the efficacy of doxorubicin to suppress hepatocellular carcinoma by downregulating HIFα and inhibiting NF-κB activity in mice	期刊论文	Wang J\|Ma Y\|Jiang H\|Zhu H\|Liu L\|Sun B\|Pan S\|Krissansen GW\|Sun X\|
14	Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo	期刊论文	Wei Z\|Jiang H\|Krissansen GW\|Xue Ying SUN\|Jiang X\|Liu F\|Qiao H\|Zhou B\|Zhai b\|Zhang L\|Zhang X\|Han L\|
15	Interaction of SDF-1 alpha and CXCR4 plays an important role in pulmonary cellular infiltration in differentiation syndrome	期刊论文	Zhou, Jin\|Hu, Longhu\|Cui, Zhe\|Jiang, Xian\|Wang, Guifang\|Krissansen, Geoffrey W.\|Sun, Xueying\|
16	The Influence of Modified Pluronic F127 Copolymers with Higher Phase Transition Temperature on Arsenic Trioxide-Releasing Properties and Toxicity in a Subcutaneous Model of Rats	期刊论文	Ma, Yong\|Zhang, Chi\|Chen, Xiaoning\|Jiang, Hongchi\|Pan, Shangha\|Easteal, Allan J.\|Sun, Xueying\|
17	Oral Administration of Lactoferrin Attenuates Intestinal Ischemia Reperfusion Injury in Rats	期刊论文	Zhang T\|Zhang F\|Wang Y\|Ban R\|Tong L\|Qiao H\|Lao H\|Zhao H\|Jiang X\|Xue Ying SUN\|
18	The protective role of hydrogen sulfide in myocardial ischemia-reperfusion-induced injury in diabetic rats	期刊论文	Gao, Yan\|Yao, Xiaoyi\|Zhang, Yina\|Li, Weimin\|Kang, Kai\|Sun, Liang\|Sun, Xueying\|
19	Hydrogen Sulfide Protects Cardiomyocytes from Myocardial Ischemia-Reperfusion Injury by Enhancing Phosphorylation of Apoptosis Repressor with Caspase Recruitment Domain	期刊论文	Yao, Xiaoyi\|Tan, Gang\|He, Changjun\|Gao, Yan\|Pan, Shangha\|Jiang, Hongchi\|Zhang, Yina\|Sun, Xueying\|
20	Downregulating hypoxia-inducible factor-2a improves the efficacy of doxorubicin in the treatment of hepatocellular carcinoma	期刊论文	He, Changjun\|Sun, Xueying\|Sun, Xue-Pu\|Qiao, Haiquan\|Jiang, Xian\|Wang, Dongdong\|Jin, Xiangguo\|Dong, Xuesong\|Wang, Jizhou\|Jiang, Hongchi\|

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