LncRNA-ST3763/STAT3在急性髓系白血病发生发展中的作用机制研究
81770186
2017
H0809.白血病
吴庆运
面上项目
教授
徐州医科大学
55万元
急性髓系白血病;STAT3;长链非编码RNA-ST3763;干性维持;白血病干细胞
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Loss of K607 and E877 interaction is a key reason for JAK2 K607N mutation caused acute myeloid leukemia. | 期刊论文 | Wu Qing-Yun;Ma Meng-Meng;Zhang Sen;Liu Yang;Cao Jiang;Yan Zhi-Ling;Li Zhen-Yu;Zeng Ling-Yu;Wang Xiao-Yun;Li Feng;Xu Kai-Lin |
| 2 | Disruption of R867 and Y613 interaction plays key roles in JAK2 R867Q mutation caused acute leukemia | 期刊论文 | Wu Qing Yun;Ma Meng Meng;Zhang Sen;Cao Jiang;Yan Zhi Ling;Chen Chong;Li Zhen Yu;Zeng Ling Yu;Wang Xiao Yun;Li Feng;Xu Kai Lin |
| 3 | Roles of germline JAK2 activation mutation JAK2 V625F in the pathology of myeloproliferative neoplasms. | 期刊论文 | Wu Qing-Yun;Ma Meng-Meng;Fu Lin;Zhu Yuan-Yuan;Liu Yang;Cao Jiang;Zhou Ping;Li Zhen-Yu;Zeng Ling-Yu;Li Feng;Wang Xiao-Yun;Xu Kai-Lin |
| 4 | Effects of JAK2 V556F mutation on the JAK2's activity, structural stability and the transformation of Ba/F3 cells. | 期刊论文 | Wu Qing-Yun;Ma Meng-Meng;Tong Yu-Xue;Zhu Yuan-Yuan;Liu Yang;Cao Jiang;Zhou Ping;Li Zhen-Yu;Zeng Ling-Yu;Wang Xiao-Yun;Li Feng;Xu Kai-Lin |
| 5 | 急性淋巴细胞白血病小鼠模型及建模方法 | 专利 | 陈翀;徐开林;祁娜;王雪;吴庆运;曾令宇;曹江;闫志凌;李振宇 |
| 6 | Roles of T875N somatic mutation in the activity, structural stability of JAK2 and the transformation of OCI-AML3 cells | 期刊论文 | Chen Chong;Li Feng;Ma Meng Meng;Zhang Sen;Liu Yang;Yan Zhi Ling;Chen Wei;Cao Jiang;Zeng Ling Yu;Wang Xiao Yun;Xu Kai Lin;Wu Qing Yun |
| 7 | 造血干细胞移植并发症防治新策略的探索与应用 | 奖励 | 徐开林;曾令宇;曹江;陈翀;赵恺;吴庆运;李振宇;闫志凌;程海;潘彬;陈伟;桑威 |
| 8 | 白血病干细胞干性形成机制及靶点特异性药物研究 | 奖励 | 吴庆运;徐开林;陈翀;赵恺;曾令宇;曹江;李风;李振宇;姚瑶 |
| 9 | Mutation of the conserved G66 residue in GS region decreased structural stability and activity of arginine kinase. | 期刊论文 | Wu Qing-Yun;Zhu Yuan-Yuan;Wei Fang;Tong Yu-Xue;Cao Jiang;Zhou Ping;Li Zhen-Yu;Zeng Ling-Yu;Li Feng;Wang Xiao-Yun;Xu Kai-Lin |
| 10 | CEP55 promoted the migration, invasion and neuroshpere formation of the glioma cell line U251 | 期刊论文 | Li Feng;Jin Dan;Guan Li;Zhang Cheng-Chen;Wu Ting;Wang Yu-Jue;Gao Dian-Shuai |
| 11 | CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia. | 期刊论文 | Wu Qing-Yun;Zhu Yuan-Yuan;Liu Yang;Wei Fang;Tong Yu-Xue;Cao Jiang;Zhou Ping;Niu Ming-Shan;Li Zhen-Yu;Zeng Ling-Yu;Li Feng;Xu Kai-Lin |
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