抗蛇毒蛋白PLIγ的分子改造及模拟肽设计

31460227
2014
C0505.蛋白质、多肽与酶生物化学
黄春洪
地区科学基金项目
教授
南昌大学
50万元
DNA改组;分子改造;蛋白质结构与功能;PLA2;蛇毒;抑制剂
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Inactivation of Venom PLA(2) Alleviates Myonecrosis and Facilitates Muscle Regeneration in Envenomed Mice: A Time Course Observation 期刊论文 Xiao Huixiang;Li Haoran;Zhang Denghong;Li Yuanyuan;Sun Shimin;Huang Chunhong
2 华游蛇PLIγ的毕赤酵母表达及其抗蛇毒sPLA2活性 期刊论文 李婧婧;李兴章;孙士民;张登虹;黄春洪
3 Exploration of the Inhibitory Potential of Varespladib for Snakebite Envenomation 期刊论文 Wang Yiding;Zhang Jing;Zhang Denghong;Xiao Huixiang;Xiong Shengwei;Huang Chunhong
4 Orthogonal optimization of prokaryotic expression of a natural snake venom phospholipase A2 inhibitor from Sinonatrix annularis 期刊论文 Zhen Le;XingZhang Li;Peng Yuan;Pi Liu;Chunhong Huang
5 The inhibitory effect of saPLI gamma, a snake sourced PLA(2) inhibitor on carrageenan-induced inflammation in mice 期刊论文 Zhang Denghong;Li Jingjing;Sun Shimin;Huang Chunhong
6 High activity chimeric snake gamma-type phospholipase A(2) inhibitor created by DNA shuffling 期刊论文 Sun Shimin;Zhang Denghong;Zhang Jing;Huang Chunhong;Xiong Ying
7 Isolation and biochemical characterization of a gamma-type phospholipase A(2) inhibitor from Macropisthodon rudis snake serum 期刊论文 Zhong Lipeng;Huang Chunhong
8 Preparation of monoclonal antibodies against gamma-type phospholipase A(2) inhibitors and immunodetection of these proteins in snake blood 期刊论文 Li Jingjing;Xiong Ying;Sun Shimin;Yu Lehan;Huang Chunhong
9 Investigation of the inhibitory potential of phospholipase A(2) inhibitor gamma from Sinonatrix annularis to snake envenomation 期刊论文 Xiong Shengwei;Luo Yunyun;Zhong Lipeng;Xiao Huixiang;Pan Hong;Liao Keren;Yang Mengxue;Huang Chunhong
10 Synergistic strategies of predominant toxins in snake venoms 期刊论文 Xiong Shengwei;Huang Chunhong
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