新型松香基苯并咪唑类微管蛋白聚合抑制剂的合成、构效关系及抗肿瘤机制研究

31770616
2017
C1604.林产化学
谷文
面上项目
教授
南京林业大学
60万元
松香衍生物;树脂酸;微管蛋白聚合抑制剂;抗肿瘤机制;构效关系
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Synthesis, Crystal Structure and Antibacterial Activity of New N-(1H-benzo[d]imidazol-2-yl)benzenesulfonamide Derivatives of Dehydroabietic Acid 期刊论文 Cai Xumin;Li Aliang;Lin Yuting;Wang Wenyan;Wang Shifa;Gu Wen
2 Syntheses, Crystal Structures and Antibacterial Activities of Two New Methyl 12-Alkylamino-13,14- dinitrodeisopropyl-dehydroabietates 期刊论文 Chen Hao;Geng Yi;Wang Shifa;Gu Wen
3 一类具有抗肿瘤活性的脱氢枞酸芳胺基苯并咪唑衍生物及其制备方法和应用 专利 谷文;陈浩;刘世泽;李阿良;王文燕;王石发
4 一种脱氢枞酸苯并咪唑-2-苯甲酰胺衍生物及其制备方法和应用 专利 谷文;李阿良;杨亚群;王文燕;刘青松;孙月;王石发
5 Design, synthesis, and anticancer evaluation of novel indole derivatives of ursolic acid as potential topoisomerase II inhibitors 期刊论文 A-Liang Li;Yun Hao;Wen-Yan Wang;Qing-Song Liu;Yue Sun;Wen Gu
6 Synthesis, anticancer evaluation and mechanism studies of novel indolequinone derivatives of ursolic acid 期刊论文 Wenyan Wang;Wenyi Wu;Aliang Li;Qingsong Liu;Yue Sun;Wen Gu
7 Synthesis, cytotoxicity and apoptosis-inducing activity of novel1H-benzo[d]imidazole derivatives of dehydroabietic acid 期刊论文 Li A-Liang;Yang Ya-Qun;Wang Wen-Yan;Liu Qing-Song;Sun Yue;Gu Wen
8 Synthesis and anticancer evaluation of novel 1H-benzo[d]imidazole derivatives of dehydroabietic acid as PI3Kα inhibitors 期刊论文 Ya-Qun Yang;Hao Chen;Qing-Song Liu;Yue Sun;Wen Gu
9 一类含杂环的脱氢枞基甲酰胺类化合物及其制备方法和应用 专利 谷文;杨子辉;刘青松;孙月;王石发;孙雪宝;孙露;陈霖霖
10 Design, synthesis, and antifungal activity of novel thiophene/furan-1,3,4-oxadiazole carboxamides as potent succinate dehydrogenase inhibitors 期刊论文 Zi-Hui Yang;Yue Sun;Qing-Song Liu;A-Liang Li;Wen-Yan Wang;Wen Gu
11 Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors 期刊论文 Jin Xiao-Yan;Chen Hao;Li Dong-Dong;Li A-Liang;Wang Wen-Yan;Gu Wen
12 一种脱氢枞酸苯并咪唑-2-苯磺酰胺衍生物及其制备方法和应用 专利 谷文;李阿良;杨亚群;王文燕;刘青松;孙月;王石发
13 A novel dehydroabietic acid-based fluorescent probe for detection of Fe3+ and Hg2+ ions and its application in live-cell imaging 期刊论文 Aliang Li;Zhonglong Wang;Wenyan Wang;Qingsong Liu;Yue Sun;Shifa Wang;Wen Gu
14 Synthesis, in vitro Antimicrobial, and Cytotoxic Activities of New 1,3,4-Oxadiazin-5(6H)-one Derivatives from Dehydroabietic Acid 期刊论文 Jin Xiao-Yan;Zhang Kang-Ping;Chen Hao;Miao Ting-Ting;Wang Shi-Fa;Gu Wen
15 一种熊果酸吲哚醌基类衍生物及其制备方法和应用 专利 谷文;王文燕;李阿良;王石发;刘青松;孙月
16 Synthesis and biological evaluation of 2-aryl- benzimidazole derivatives of dehydroabietic acid as novel tubulin polymerization inhibitors 期刊论文 Miao Ting-Ting;Tao Xu-Bing;Li Dong-Dong;Chen Hao;Jin Xiao-Yan;Geng Yi;Wang Shi-Fa;Gu Wen
17 Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitors 期刊论文 Chen Hao;Qiao Chao;Miao Ting-Ting;Li A-Liang;Wang Wen-Yan;Gu Wen
18 一种脱氢枞酸基2,4-二芳基苯并咪唑类亚硫酸氢根离子荧光探针及其制备方法和应用 专利 谷文;李阿良;王忠龙;王文燕;刘青松;孙月;王石发
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