基于多学科融合技术的分子探针在膀胱癌精准诊疗中的应用研究
U20A20385
2020
H2706.分子影像
徐万海
联合基金项目
教授
哈尔滨医科大学
260万元
分子影像;膀胱癌;精准诊疗;多组学;纳米医学
2021-01-01到2024-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | An Ultrasound-Induced Self-Clearance Hydrogel for Male Reversible Contraception | 期刊论文 | Zi-Qi Wang;Zhong-Qing Liu;Chang-Hao Zhao;Kuo Zhang;Zhi-Jian Kang;Tian-Rui Qu;Fan-Shu Zeng;Peng-Yu Guo;Zhi-Chao Tong;Chang-Lin Wang;Ke-Liang Wang;Hong-Lei Wang;Yin-Sheng Xu;Wan-Hui Wang;Mao-lin Chu;Lu Wang;Zeng-Ying Qiao;Hao Wang;Wanhai Xu |
| 2 | An activated excretion-retarded tumor imaging strategy towards metabolic organs | 期刊论文 | Da-Yong Hou;Man-Di Wang;Xing-Jie Hu;Zhi-Jia Wang;Ni-Yuan Zhang;Gan-Tian Lv;Jia-Qi Wang;Xiu-Hai Wu;Lu Wang;Hao Wang;Wanhai Xu |
| 3 | PKM2四聚体变构激活肽及其在肿瘤中逆转Warburg效应和化疗增敏中的应用 | 专利 | 徐万海;王璐;王浩;李莉莉;侯大勇;吕玉林;付博;杨光;于家傲 |
| 4 | 一种形状记忆尿道支架 | 专利 | 刘彦菊;徐万海;冷劲松;耿强旺;张风华;王子琦;王科亮 |
| 5 | PKM2 allosteric converter: A self-assembly peptide for suppressing renal cell carcinoma and sensitizing chemotherapy | 期刊论文 | Lu Wang;Bo Fu;Da-Yong Hou;Yu-Lin Lv;Guang Yang;Cong Li;Jia-Chen Shen;Bin Kong;Li-Bo Zheng;Yu Qiu;Hong-Lei Wang;Chen Liu;Jian-Ji Zhang;Shi-Yu Bai;Li-Li Li;Hao Wang;Wan-Hai Xu |
| 6 | In Situ Constructed Nano‐Drug Depots through Intracellular Hydrolytic Condensation for Chemotherapy of Bladder Cancer | 期刊论文 | Da‐Yong Hou;Ni‐Yuan Zhang;Man‐Di Wang;Shao‐Xin Xu;Zhi‐Jia Wang;Xing‐Jie Hu;Gan‐Tian Lv;Jia‐Qi Wang;Xiu‐Hai Wu;Lu Wang;Dong‐Bing Cheng;Hao Wang;Wanhai Xu |
| 7 | 一种防倒流的输尿管支架 | 专利 | 徐万海;刘彦菊;耿强旺;张风华;王子琦;冷劲松 |
| 8 | Engineered Macrophages Tune Intratumoral Cytokines through Precisely Controlled Self‐Pyroptosis to Enhance Bladder Cancer Immunotherapy | 期刊论文 | Pengyu Guo;Peng Dai;Shenghao Yang;Ziqi Wang;Zhichao Tong;Dayong Hou;Xiao Liu;Wanhai Xu |
| 9 | Transformable ECM Deprivation System Effectively Suppresses Renal Cell Carcinoma by Reversing Anoikis Resistance and Increasing Chemotherapy Sensitivity (Adv. Mater. 43/2022) | 期刊论文 | Lu Wang;Cong Li;Jiaqi Wang;Guang Yang;Yulin Lv;Bo Fu;Lingrui Jian;Jinpeng Ma;Jiaao Yu;Zongzheng Yang;Peng Wu;Guangbin Li;Xiao Liu;Zhijian Kang;Ziqi Wang;Lei Wang;Hao Wang;Wanhai Xu |
| 10 | Inducing mitochondriopathy-like damages by transformable nucleopeptide nanoparticles for targeted therapy of bladder cancer | 期刊论文 | Da-Yong Hou;Ni-Yuan Zhang;Lu Wang;Mei- Yu Lv;Xiang-Peng Li;Peng Zhang;Yue-Ze Wang;Lei Shen;Xiu-Hai Wu;Bo Fu;Peng- Yu Guo;Zi-Qi Wang;Dong-Bing Cheng;Hao Wang;Wanhai Xu |
| 11 | In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux | 期刊论文 | Lv Yulin;Song Benli;Yang Guang;Wang Yuting;Wu Zeyu;Si Minggui;Yang Zongzheng;Chen Huilin;Liu Chen;Li Min;Zhang Yinshi;Qiao Zengying;Wang Lu;Xu Wanhai |
| 12 | 一种硬管内窥镜及物镜管 | 专利 | 徐万海;王子琦;岑建;左鹏飞;李辉;聂鲁愚 |
| 13 | A Lysosome-Targeting Self-Condensation Prodrug-Nanoplatform System for Addressing Drug Resistance of Cancer | 期刊论文 | Da-Yong Hou;Man-Di Wang;Ni-Yuan Zhang;Shaoxin Xu;Zhi-Jia Wang;Xing-Jie Hu;Gan-Tian Lv;Jia-Qi Wang;Mei-Yu Lv;Li Yi;Lu Wang;Dong-Bing Cheng;Taolei Sun;Hao Wang;Wanhai Xu |
| 14 | 一种内窥镜图像的处理方法及内窥镜成像系统 | 专利 | 徐万海;王子琦;左鹏飞;岑建;陈聪平;李洋 |
| 15 | A Transformable Specific‐Responsive Peptide for One‐Step Synergistic Therapy of Bladder Cancer | 期刊论文 | Zi‐Qi Wang;Tian‐Rui Qu;Zhi‐Shuai Zhang;Fan‐Shu Zeng;Hong‐Jian Song;Kuo Zhang;Pengyu Guo;Zhichao Tong;Da‐Yong Hou;Xiao Liu;Lu Wang;Hao Wang;Wanhai Xu |
| 16 | Engineering Nanosensitizer to Remodel the TME for Hypoimmunogenic “Cold”–“Hot” Tumor Transformations | 期刊论文 | Zhongqing Liu;Ziqi Wang;Zhishuai Zhang;Zhenwei Zhang;Xin Qi;Hanwen Zhu;Kuo Zhang;Tianrui Qu;Yubo Zhao;Zhijian Kang;Fanshu Zeng;Pengyu Guo;Zhichao Tong;Lu Wang;Hao Wang;Wanhai Xu |
| 17 | Self‐Disguised Nanospy for Improving Drug Delivery Efficiency via Decreasing | 期刊论文 | Kuo Zhang;Zi‐Qi Wang;Zhongqing Liu;Tianrui Qu;Zhishuai Zhang;Fanshu Zeng;Hongjian Song;Qing Shi;Zhijian Kang;Bogong Chen;Peng Dai;Pengyu Guo;Zhichao Tong;Wanhai Xu |
| 18 | OGA activated glycopeptide-based nano-activator to activate PKM2 tetramerization for switching catabolic pathways and sensitizing chemotherapy resistance | 期刊论文 | Da-Yong Hou;Wu-Yi Xiao;Jia-Qi Wang;Muhammad Yaseen;Zhi-Jia Wang;Yue Fei;Man-Di Wang;Lu Wang;Hui Wang;Xinghua Shi;Meng-meng Cai;Hai-Tao Feng;Wanhai Xu;Li-Li Li |
| 19 | 一种荧光内窥镜及一种棒镜组件 | 专利 | 徐万海;王子琦;左鹏飞;岑建;杨莉;林路易 |
| 20 | 纳米材料在泌尿系肿瘤精准诊疗中的关键技术创新与转换应用 | 奖励 | 徐万海;王浩;刘绍琴;左鹏飞;王璐;王子琦;郭鹏宇;侯大勇;刘潇 |
| 21 | 内窥镜光源的控制方法、装置及内窥镜摄像系统 | 专利 | 徐万海;王子琦;岑建;左鹏飞;王柯威;吴晓华 |
| 22 | Targeting tumour surface collage with hydrogel probe: a new strategy to enhance intraoperative imaging sensitivity and stability of bladder cancer | 期刊论文 | Guo Pengyu;Qi Ao;Shang Wenting;Cai Zehao;Hu Sheng;Dai Peng;Chen Ziyin;Sun Mingwei;Wang Zixing;Tong Zhichao;Hou Dayong;Wang Ziqi;Du Yang;Tian Jie;Xu Wanhai |
| 23 | A bispecific glycopeptide spatiotemporally regulates tumor microenvironment for inhibiting bladder cancer recurrence | 期刊论文 | Hong-Wei An;Da-Yong Hou;Jia Yang;Zi-Qi Wang;Man-Di Wang;Rui Zheng;Ni-Yuan Zhang;Xing-Jie Hu;Zhi-Jia Wang;Lu Wang;Di Liu;Jun-Feng Hao;Wanhai Xu;Yuliang Zhao;Hao Wang |
| 24 | In vivo assembly enhanced binding effect augments tumor specific ferroptosis therapy | 期刊论文 | Da-Yong Hou;Dong-Bing Cheng;Ni-Yuan Zhang;Zhi-Jia Wang;Xing-Jie Hu;Xin Li;Mei-Yu Lv;Xiang-Peng Li;Ling-Rui Jian;Jin-Peng Ma;Taolei Sun;Zeng-Ying Qiao;Wanhai Xu;Hao Wang |
| 25 | Bispecific fibrous glue synergistically boosts vascular normalization and antitumor immunity for advanced renal carcinoma therapy | 期刊论文 | Xiu-Hai Wu;Jia-Qi Wang;Man-Di Wang;Ting Xiao;Yu Wang;Jia-Yuan Niu;Lu Wang;Da-Yong Hou;Bo Fu;Zimo Liu;Hao Wang;Wanhai Xu |
| 26 | Nano Proteolysis Targeting Chimeras (PROTACs) with Anti‐Hook Effect for Tumor Therapy | 期刊论文 | Ni-Yuan Zhang;Da-Yong Hou;Xing-Jie Hu;Jian-Xiao Liang;Man-Di Wang;Zhang-Zhi Song;Li Yi;Zhi-Jia Wang;Hong-Wei An;Wanhai Xu;Hao Wang |
| 27 | 一种超声响应性复合水凝胶及其制备方法和应用 | 专利 | 徐万海;王浩;王子琦;乔增莹;刘忠清;赵昌浩 |
| 28 | In Vivo Self‐Assembled Bispecific Nano‐Blocker for Enhancing Tumor Immunotherapy | 期刊论文 | Xing‐Jie Hu;Ni‐Yuan Zhang;Da‐Yong Hou;Zhi‐Jia Wang;Man‐Di Wang;Li Yi;Zhang‐Zhi Song;Jian‐Xiao Liang;Xiang‐Peng Li;Hong‐Wei An;Wanhai Xu;Hao Wang |
| 29 | 一种纤连蛋白靶向多肽及其在促进肿瘤失巢凋亡及化疗增敏中的应用 | 专利 | 徐万海;王璐;王浩;王磊;王佳起;李聪;郑力波 |
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