基于质谱-分子网络策略的柳珊瑚来源真菌环肽活性先导物发现

81874300
2018
H3405.海洋药物
王长云
面上项目
教授
中国海洋大学
60万元
次级代谢产物;柳珊瑚来源真菌;质谱-分子网络;促血管新生;环肽
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Identification of marine natural product pretrichodermamide B as a STAT3 inhibitor for efficient anticancer therapy 期刊论文 Rui Li;Yue Zhou;Xinxin Zhang;Lujia Yang;Jieyu Liu;Samantha M. Wightman;Ling Lv;Zhiqing Liu;Chang-Yun Wang;Chenyang Zhao
2 Targeted isolation of asperheptatides from a coral-derived fungus using LC-MS/MS-based molecular networking and antitubercular activities of modified cinnamate derivatives. 期刊论文 Rong Chao;Xue-Mei Hou;Wei-Feng Xu;Yang Hai;Mei-Yan Wei;Chang-Yun Wang;Yu-Cheng Gu;Chang-Lun Shao
3 Discovery of Quinazolinone Derivatives as Novel Acetylcholinesterase (AchE) Inhibitors via Scaffold Hopping. 会议论文 Mireguli Maimaitiming;Ling Lv;Shuxia Chen;Yanfeng Sun;Yan Huang;Huaxuan Li;Zhiqing Liu;Changyun Wang
4 多功能抗菌化合物及其制备与应用方法及中间体 专利 王长云;刘志清;王岩;李浩然;王影松;李钰莹
5 A new azaphilone derivative from a zoanthid-derived fungus Cladosporium oxysporum 会议论文 Xiao-Han Liu;Chao-Yi Wang;Chang-Yun Wang
6 An anti-MRSA cyclopeptolide from the marine-derived fungus Cochliobolus lunatus 会议论文 Jing-Shuai Wu;Chang-Lun Shao;Chang-Yun Wang
7 Mining Novel Active Secondary Metabolites from the Deep-sea-derived Fungus Penicillium janthinellum 会议论文 Zhi-Pu Yu;Chang-Yun Wang;Chang-Lun Shao;Yu-Cheng Gu
8 Identification of Diketopiperazines as STAT3 Inhibitors from marine-derived fungus Penicillium janthinellum. 会议论文 Yue Zhou;Rui Li;Lu-Jia Yang;Xin-Xin Zhang;Yan-Feng Sun;Jie-Yu Liu;ZhiQing Liu;Chen-Yang Zhao;Chang-Yun Wang
9 二酮哌嗪类天然产物及衍生物的应用、制备与所得衍生物 专利 王长云;刘志清;杨金波;赵晨阳;王平原;周月;李锐;张心心;杨路佳
10 Discovery of Dual-Acting Immune-Antimicrobial Agents via Hybrid Strategy. 会议论文 Hao-Ran Li;Yan Huang;Ling Lv;Yao-Yao Zheng;Shu-Yue Song;Zhong-Lian Ma;Zhi-Qing Liu;Chang-Yun Wang
11 Discovery of marine natural products as promising antibiotics against Pseudomonas aeruginosa 期刊论文 Haoran Li;Mireguli Maimaitiming;Yue Zhou;Huaxuan Li;Pingyuan Wang;Yang Liu;Till F. Schäberle;Zhiqing Liu;Chang-Yun Wang
12 Targeted isolation of antitubercular cycloheptapeptides and an unusual pyrroloindoline‑containing new analog, asperpyrroindotide A, using LC–MS/MS‑based molecular networking 期刊论文 Yi‑Qian Han;Qun Zhang;Wei‑Feng Xu;Yang Hai;Rong Chao;Cui‑Fang Wang;Xue‑Mei Hou;Mei‑Yan Wei;Yu‑Cheng Gu;Chang‑Yun Wang;Chang‑Lun Shao
13 Discovery and biological evaluation of small molecular marine natural products 会议论文 Zhi-Qing Liu;Lu Liu;Chang-Lun Shao;Chang-Yun Wang
14 Thiodiketopiperazines from a deep-sea derived fungus 会议论文 Lu-Jia Yang;Yu-Cheng Gu;Chang-Lun Shao;Chang-Yun Wang
15 Studies of sulfurated diketopiperazines from the deep-sea-derived fungus Penicillium janthinellum. 会议论文 Zhi-Pu Yu;Chang-Yun Wang;Chang-Lun Shao;Yu-Cheng Gu
16 Integrating molecular networking and 1H NMR to target the isolation of chrysogeamides from a library of marine-derived Penicillium fungi 期刊论文 Xue-Mei Hou;Yue-Ying Li;Yun-Wei Shi;Yao-Wei Fang;Rong Chao;Yu-Cheng Gu;Chang-Yun Wang;Chang-Lun Shao
17 Briarane-type diterpenoids from gorgonian Dichotella gemmacea GX-BH-WZ-3 会议论文 Bao Chen;Chang-Yun Wang;Chang-Lun Shao;Yu-Cheng Gu
18 Thiodiketopiperazines from the deep-sea derived fungus Penicillum janthinellum 会议论文 Lu-Jia Yang;Chang-Yun Wang;Chang-Lun Shao;Yu-Cheng Gu
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