外泌体介导miR-23b分选拮抗Infliximab治疗类风湿性关节炎的调控机制探索

81872928
2018
H3510.药物代谢与药物动力学
李全顺
面上项目
教授
吉林大学
57万元
疾病调控机制;药物代谢;小核酸;类风湿性关节炎;外泌体
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Urate oxidase-loaded in PCN-222(Fe) with peroxidase-like activity for colorimetric detection of uric acid 期刊论文 Xiao Liang;Yingxuan Chen;Kai Wen;Haobo Han;Quanshun Li
2 Oral administration of therapeutic enzyme capsule for the management of inflammatory bowel disease 期刊论文 Xiao Liang;Kai Wen;Yingxuan Chen;Guangxu Fang;Shengcai Yang;Quanshun Li
3 Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats 期刊论文 Haobo Han;Jiakai Xing;Wenqi Chen;Jiaxin Jia;Quanshun Li
4 Immobilized lipase in bio-based metal-organic frameworks constructed by biomimetic mineralization: a sustainable biocatalyst for biodiesel synthesis 期刊论文 Qing Li;Yingxuan Chen;Shaowei Bai;Xinxin Shao;Lin Jiang;Quanshun Li
5 球孢白僵菌孢子-杂化纳米花生物农药、制备方法及应用 专利 李全顺;史植元;路杨;张正坤;李启云;隋丽;杜茜;赵宇
6 Genome editing of PD-L1 mediated by nucleobase-modified polyamidoamine for cancer immunotherapy 期刊论文 Simeng Wei;Xinxin Shao;Yong Liu;Boyu Xiong;Pengfei Cui;Ziling Liu;Quanshun Li
7 Fluoropolymer-mediated intracellular delivery of miR-23b for the osteocyte differentiation in osteoblasts 期刊论文 Sihan Wang;Jiakai Xing;Boyu Xiong;Haobo Han;Min Hu;Quanshun Li
8 Dual ATP/reduction-responsive polyplex to achieve the co-delivery of doxorubicin and miR-23b for the cancer treatment 期刊论文 Xiuhui Tang;Xiao Liang;Kai Wen;Yingxuan Chen;Haobo Han;Quanshun Li
9 一种多羟基聚氨酯蛋白质转染试剂、制备方法及其应用 专利 李全顺;梁骁;温凯;姜伟;陈英翾;韩浩博
10 Immobilized enzymes in inorganic hybrid nanoflowers for biocatalytic and biosensing applications 期刊论文 Xiao Liang;Yong Liu;Kai Wen;Wei Jiang;Quanshun Li
11 A comprehensive review on histone-mediated transfection for gene therapy 期刊论文 Haobo Han;Jiebing Yang;Wenqi Chen;Qing Li;Yan Yang;Quanshun Li
12 Phenylboronic acid-functionalized polyamidoamine-mediated miR-34a delivery for the treatment of gastric cancer 期刊论文 Zeyu Song;Xiao Liang;Yudi Wang;Haob Han;Jiebing Yang;Xuedong Fang;Quanshun Li
13 Superoxide dismutase-embedded metal-organic frameworks via biomimetic mineralization for the treatment of inflammatory bowel disease 期刊论文 Shaowei Bai;Yu Tao;Xinxin Shao;Song Wang;Haobo Han;Quanshun Li
14 Artesunate-loaded porous PLGA microsphere as a pulmonary delivery system for the treatment of non-small cell lung cancer 期刊论文 Boyu Xiong;Yanxu Chen;Yong Liu;Xiaolin Hu;Haobo Han;Quanshun Li
15 N-Isopropylacrylamide-modified polyethylenimine-mediated miR-29a delivery to inhibit the proliferation and migration of lung cancer cells 期刊论文 Jiakai Xing;Jiaxin Jia;Xiaofeng Cong;Ziling Liu;Quanshun Li
16 Phenylboronic acid-modified polyamidoamine-mediated the transfection of Polo-like kinase-1 siRNA to achieve an anti-tumor efficacy 期刊论文 Gu Gong;Xiuhui Tang;Jiayuan Zhang;Xiao Liang;Jiebing Yang;Quanshun Li
17 Immobilization of urease in metal-organic frameworks via biomimetic mineralization and its application in urea degradation 期刊论文 Xiao Liang;Qing Li;Zhiyuan Shi;Shaowei Bai;Quanshun Li
18 A genipin-crosslinked protein-polymer hybrid system for the intracellular delivery of ribonuclease A 期刊论文 Xiao Liang;Xiuhui Tang;Jiebing Yang;Jiayuan Zhang;Haobo Han;Quanshun Li
19 Nano-scaled zeolitic imidazole framework-8 as an efficient carrier for the intracellular delivery of RNase A in cancer treatment 期刊论文 Jiaxin Jia;Shudi Zhang;Kai Wen;Quanshun Li
20 一种具有抗衰老作用的外泌体-超氧化物歧化酶纳米制剂及其制备方法 专利 李全顺;邵新欣;李青;刘勇;梁骁
21 Phenylboronic acid-modified polyamidoamine-mediated delivery of short GC rich DNA for hepatocarcinoma gene therapy 期刊论文 Jiebing Yang;Jiayuan Zhang;Yong Liu;Zhiyuan Shi;Haobo Han;Quanshun Li
22 Immobilization of thermophilic lipase in inorganic hybrid nanoflower through biomimetic mineralization 期刊论文 Yong Liu;Xinxin Shao;Deqiang Kong;Guangquan Li;Quanshun Li
23 Nucleolin-targeting AS1411 aptamer-modified micelle for the co-delivery of doxorubicin and miR-519c to improve the therapeutic efficacy in hepatocellular carcinoma treatment 期刊论文 Xiao Liang;Yudi Wang;Hui Shi;Mengmeng Dong;Haobo Han;Quanshun Li
24 Inhibition of proliferation and migration of tumor cells through phenylboronic acid-functionalized polyamidoamine-mediated delivery of a therapeutic DNAzyme Dz13 期刊论文 Jiebing Yang;Jiayuan Zhang;Jiakai Xing;Zhiyuan Shi;Haobo Han;Quanshun Li
25 Reactive oxygen species-mediated inflammation and apoptosis in hand-foot syndrome induced by PEGylated liposomal doxorubicin 期刊论文 Xiaolin Hu;Mengmeng Dong;Xiao Liang;Ziling Liu;Quanshun Li
26 Inhibition of proliferation and migration of tumor cells through lipoic acid-modified oligoethylenimine-mediated p53 gene delivery 期刊论文 Xiuhui Tang;Qing Li;Xiao Liang;Jiebing Yang;Ziling Liu;Quanshun Li
27 Lipoic acid-modified oligoethyleneimine-mediated miR-34a delivery to achieve the anti-tumor efficacy 期刊论文 Yu Huang;Longxiang Wang;Yingxuan Chen;Haob Han;Quanshun Li
28 A chemoenzymatically synthesized cholesterol-g-poly(amine-co-ester)-mediated p53 gene delivery for achieving antitumor efficacy in prostate cancer 期刊论文 Mengmeng Dong;Jiawen Chen;Jiayuan Zhang;Xiao Liang;Jiebing Yang;Dan Li;Quanshun Li
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