m6A RNA去甲基化酶FTO介导的RNA表观遗传调控PDL1在白血病酪氨酸激酶抑制剂耐药中的研究

81870117
2018
H0809.白血病
闫飞
面上项目
副教授
吉林大学
57万元
药物耐受;m6A;RNA甲基化;PDL1;酪氨酸激酶抑制剂;白血病
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Gold Nanorods Exhibit Intrinsic Therapeutic Activity via Controlling N6-Methyladenosine-Based Epitranscriptomics in Acute Myeloid Leukemia 期刊论文 Yangyang Du;Mingda Han;Kunxia Cao;Qing Li;Jiuxia Pang;Liping Dou;Shujun Liu;Zhan Shi;Fei Yan;Shouhua Feng
2 Decitabine-Loaded Gold Nanocages for Photothermal Cancer Therapy via DNA Hypermethylation Reversal 期刊论文 Yan Sun;Songcai Liu;Yuan Gao;Yangyang Du;Hongqiao Cai;Jian Zhang;Zhaoguo Wang;Xi Yang;Linlin Hao;Fei Yan
3 Gold Nanorod–Mesoporous Silica Core Shell Nanocomposites for NIR-II Photothermal Ablation and Dual PD-L1/VEGF Blockade Therapy in Hepatocellular Carcinoma 期刊论文 Xinlun Dai;Xin Li;Yangyang Du;Mingda Han;Zhihua Wang;Yiqiao Wang;Fei Yan;Yahui Liu
4 Bortezomib-Encapsulated CuS/Carbon Dot Nanocomposites for Enhanced Photothermal Therapy via Stabilization of Polyubiquitinated Substrates in the Proteasomal Degradation Pathway 期刊论文 Ying Yu;Meiyu Song;Cailing Chen;Yangyang Du;Chunguang Li;Yu Han;Fei Yan;Zhan Shi;Shouhua Feng
5 Multifunctional Gold Nanoparticles Overcome MicroRNA Regulatory Network Mediated-Multidrug Resistant Leukemia 期刊论文 Rong Deng;Bai Ji;Hongliang Yu;Wei Bao;Zhuoqi Yang;Ying Yu;Yahan Cui;Yangyang Du;Meiyu Song;Shujun Liu;Kamel Meguellati;Fei Yan
6 Hepcidin-Based Nanocomposites for Enhanced Cancer Immunotherapy by Modulating Iron Export-Mediated N6-Methyladenosine RNA Transcript 期刊论文 Lingxiao Zhang;Yue Song;Kunxia Cao;Yangyang Du;Mingda Han;Zhan Shi;Fei Yan;Shouhua Feng
7 Tumor-Associated-Macrophage-Membrane-Coated Nanoparticles for Improved Photodynamic Immunotherapy 期刊论文 Cailing Chen;Meiyu Song;Yangyang Du;Ying Yu;Chunguang Li;Yu Han;Fei Yan;Zhan Shi;Shouhua Feng
8 Photothermal therapy mediated by gold nanocages composed of anti-PDL1 and galunisertib for improved synergistic immunotherapy in colorectal cancer 期刊论文 Siyu Wang;Yue Song;Kunxia Cao;Lingxiao Zhang;Xuedong Fang;Fangfang Chen;Shouhua Feng;Fei Yan
9 Saikosaponin D loaded macrophage membrane-biomimetic nanoparticles target angiogenic signaling for breast cancer therapy 期刊论文 Kaiju Sun;Wenjing Yu;Bai Ji;Changbao Chen;Hongmei Yang;Yangyang Du;Meiyu Song;Hongqiao Cai;Fei Yan;Rui Su
10 Targeting N6-methyladenosine reader YTHDF1 promotes second near-infrared Nano-Photothermal immunotherapy 期刊论文 Yangyang Du;Xinlun Dai;Mingda Han;Zhihua Wang;Yiqiao Wang;Zhan Shi;Fei Yan;Shouhua Feng
11 Glycyrrhetinic acid nanoparticles combined with ferrotherapy for improved cancer immunotherapy 期刊论文 Qing Li;Rui Su;Xin Bao;Kunxia Cao;Yangyang Du;Nanya Wang;Jianfeng Wang;Fan Xing;Fei Yan;Keke Huang;Shouhua Feng
12 Self-assembled nanostructured photosensitizer with aggregation-induced emission for enhanced photodynamic anticancer therapy 期刊论文 Wenkun Han;Song Zhang;Rong Deng;Yangyang Du;Jingyu Qian;Xiaohua Zheng;Bin Xu;Zhigang Xie;Fei Yan;Wenjing Tian
13 A Bimetallic Metal–Organic Framework-Based Biomimetic Nanoplatform Enhances Anti-Leukemia Immunity via Synchronizing DNA Demethylation and RNA Hypermethylation 期刊论文 Yue Song;Lingxiao Zhang;Yiqiao Wang;Mingda Han;Zhihua Wang;Ning Wang;Bingru Shao;Runan Li;Kunxia Cao;Meiyu Song;Yangyang Du;Fei Yan
14 Hybrid membrane camouflaged copper sulfide nanoparticles for photothermal-chemotherapy of hepatocellular carcinoma 期刊论文 Bai Ji;Hongqiao Cai;Yang Yang;Fenghui Peng;Meiyu Song;Kaiju Sun;Fei Yan;Yahui Liu
15 Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia 期刊论文 Liping Dou;Fei Yan;Jiuxia Pang;Dehua Zheng;Dandan Li;Li Gao;Lijun Wang;Yihan Xu;Jinlong Shi;Qian Wang;Lei Zhou;Na Shen;Puja Singh;Lili Wang;Yonghui Li;Yvchi Gao;Tao Liu;Chongjian Chen;Aref Al Kali;Mark R Litzow;Young In Chi;Ann M Bode;Chunhui Liu;Haojie Huang;Daihong Liu;Guido Marcucci;Shujun Liu;Li Yu
16 Cyclodextrin-Functionalized Gold Nanorods Loaded with Meclofenamic Acid for Improving N6-Methyladenosine-Mediated Second Near-Infrared Photothermal Immunotherapy 期刊论文 Jianhua Liu;Yue Song;Yiqiao Wang;Mingda Han;Chunxi Wang;Fei Yan
17 Fluorescent nanorods based on 9,10-distyrylanthracene (DSA) derivatives for efficient and long-term bioimaging 期刊论文 Wenkun Han;Yangyang Du;Meiyu Song;Kaiju Sun;Bin Xu;Fei Yan;Wenjing Tian
18 Water-soluble conjugated polymeric micelles as a carrier for studying Pt(iv) release and imaging in living cells 期刊论文 Ting Yang;Jilin Liu;Zhiru Hu;Jie Jiang;Fei Yan;Guodong Feng
19 Natural Melanin/Polyurethane Composites as Highly Efficient Near-Infrared-Photoresponsive Shape Memory Implants 期刊论文 Wanjie Xie;Fei Yan;Esfandiar Pakdel;Julie Sharp;Dan Liu;Xungai Wang;Shi Zhan;Lu Sun
20 Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m(6)A signaling 期刊论文 Kaiju Sun;Yangyang Du;Yuzhu Hou;Mingyue Zhao;Jiajia Li;Yazhe Du;Lingxiao Zhang;Changbao Chen;Hongmei Yang;Fei Yan;Rui Su
21 Recent advances in nanoparticles-based photothermal therapy synergizing with immune checkpoint blockade therapy 期刊论文 Xinlun Dai;Xin Li;Yahui Liu;Fei Yan
22 Glutathione-Bioimprinted Nanoparticles Targeting of N6-methyladenosine FTO Demethylase as a Strategy against Leukemic Stem Cells 期刊论文 Kunxia Cao;Yangyang Du;Xin Bao;Mingda Han;Rui Su;Jiuxia Pang;Shujun Liu;Zhan Shi;Fei Yan;Shouhua Feng
23 一种金纳米棒复合材料及其制备方法与应用 专利 闫飞;杜阳阳
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