靶向SQSTM1/p62介导的选择性自噬及其在多发性骨髓瘤治疗和耐药中的意义

81870160
2018
H0811.骨髓瘤与浆细胞疾病
戴云
面上项目
教授
吉林大学
57万元
耐药;SQSTM1/p62;靶向治疗;多发性骨髓瘤;选择性自噬
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Decoding DNA methylation in epigenetics of multiple myeloma 期刊论文 Ting Yang;Xiaobo Liu;Shaji K. Kumar;Fengyan Jin;Yun Dai
2 Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNFa and angiogenic VEGF 期刊论文 Jin F;Zheng X;Yang Y;Yao G;Ye L;Doeppner TR;Hermann DM;Wang H;Dai Y
3 Targeting epigenetic modifiers to reprogramme macrophages in non-resolving inflammation-driven atherosclerosis 期刊论文 Fengyan Jin;Jian Li;Jianfeng Guo;Thorsten R. Doeppner;Dirk M. Hermann;Gang Yao;Yun Dai
4 The R2-ISS in a multi-center cohort of Chinese patients with newly-diagnosed multiple myeloma 期刊论文 Yang P;Zhou F;Dong Y;Gao G;Xue H;Liang X;Yu S;Xu W;Ma Y;Qin X;Li M;Dai Y;Jin F
5 Cell cycle regulation and hematologic malignancies 期刊论文 Dai Y;Jin F;Wu W;Kumar SK
6 Pegfilgrastim improves the outcomes of mobilization and engraftment in autologous hematopoietic stem cell transplantation for the treatment of multiple myeloma 期刊论文 Ding X;Huang W;Peng Y;Fan H;Zhu Y;Liu X;Yang Y;Guo Q;Qiu L;Dai Y;Zou D;Jin F
7 The adverse double-hit effect of combining cytogenetic abnormalities and ISS stage III on the outcome of patients with newly-diagnosed multiple myeloma (abs) 期刊论文 Jin F;Kumar SK;Dai Y
8 Dynamic monitoring of minimal residual disease reveals its superior prognostic significance in multiple myeloma (oral) 会议论文 Jin F;Landgren O;Dai Y
9 Dual-targeted therapy circumvents non-genetic drug resistance to targeted therapy 期刊论文 Wang W;Sun Y;Liu X;Kumar SK;Jin F;Dai Y
10 NO up-regulates migraine-related CGRP via activation of an Akt/GSK-3b/NF-kB signaling cascade in trigeminal ganglion neurons 期刊论文 Yao G;Man Y-H;Li A-R;Guo Y;Dai Y;Wang P;Zhou Y-F
11 血液衰老:定义与范畴(Blood aging: Definition and scope) 期刊论文 靳凤艳;薛华;孙亮;兰茂卓;张凌怡;张江勃;田梦茹;李玉军;黎健;戴云
12 IRF4 is reciprocally dysregulated via NF-kB-dependent expression and loss-of-function mutations in multiple myeloma (oral) 会议论文 Dai Y;Sun Y;Sun Y;Wu W;Jin F
13 IRF4 is reciprocally dysregulated via NF-kB-dependent expression and loss-of-function mutations in multiple myeloma (abs) 期刊论文 Dai Y;Sun Y;Kumar SK;Wu W;Jin F
14 TET2 down-regulation confers bortezomib resistance in multiple myeloma (abs) 期刊论文 Dai Y;Liu X;Yang T;Kumar SK;Jin F
15 Early leukoencephalopathy during daratumumab treatment in a patient with multiple myeloma 期刊论文 Liu S;Zhou H;Xu W;Jin T;Liang X;Zhao X;Dai Y;Jin F
16 Dynamic monitoring of minimal residual disease reveals its superior prognostic significance in multiple myeloma (abs) 期刊论文 Jin F;Landgren CO;Dai Y
17 Proposed risk-scoring model for estimating the prognostic impact of 1q gain in patients with newly diagnosed multiple myeloma 期刊论文 Yang P;Chen H;Liang X;Xu W;Yu S;Huang W;Yi X;Guo Q;Tian M;Yue T;Li M;Zhang Y;Zhang M;Yan Y;Hu Z;Kumar SK;Zhou F;Dai Y;Jin F
18 Dynamic monitoring of minimal residual disease in newly-diagnosed multiple myeloma 期刊论文 Yang P;Xu W;Liang X;Yu S;Yi X;Liu M;Tian M;Yue T;Zhang Y;Yan Y;Hu Z;Guo Q;Zhang N;Wang J;Sun X;Hu R;Kumar SK;Dai Y;Jin F
19 The prognostic value of the MASS in a multi-center cohort of patients with newly-diagnosed multiple myeloma 期刊论文 Yang P;Zhou F;Dong Y;Gao G;Xue H;Liang X;Yu S;Xu W;Ma Y;Qin X;Li M;Dai Y;Jin F
20 A multi-center epidemiological and prognostic analysis of cytogenetic abnormalities in a cohort of 1015 Chinese patients with newly-diagnosed multiple myeloma (abs) 期刊论文 Jin F;Gao G;Dong Y;Li C;Huang W;Zhang L;Zhu Q;Yuan R;Xu L;Xu Y;Xu Q;Kumar SK;Dai Y
21 Detection of host cell gene/HPV DNA methylation markers: A promising triage approach for cervical cancer 期刊论文 Zhang L;Tan W;Yang H;Zhang S;Dai Y
22 Poly-ADP-ribose polymerase (PARP) inhibitors and ovarian function 期刊论文 Li J;Li Q;Zhang L;Zhang S;Dai Y
23 The mechanisms and therapeutic targets of ferroptosis in cancer 期刊论文 Long Ye;Fengyan Jin;Shaji K. Kumar;Yun Dai
24 Diverse epigenetic regulations of macrophages in atherosclerosis 期刊论文 Yang H;Sun Y;Li Q;Jin F;Dai Y
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