法尼醇X受体介导的NLRP3炎症小体组装抑制途径在黄芪甲苷保护顺铂急性肾损伤中的作用机制研究

81803608
2018
H3509.血液、泌尿与生殖系统药物药理
曲晓宇
青年科学基金项目
副主任药师
吉林大学
21万元
Nod样受体蛋白3;急性肾损伤;法尼醇X受体;黄芪甲苷;顺铂
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 OCT2/MRP2在黄芪甲苷联合顺铂的减毒增效作用中的机制研究 期刊论文 曲晓宇;翟婧卉;高欢;陶娌娜;张月明;巩佳威;宋燕青
2 Omeprazole protects against cisplatin-induced nephrotoxicity by alleviating oxidative stress, inflammation, and transporter-mediated cisplatin accumulation in rats and HK-2 cells 期刊论文 Gao Huan;Zhang Sixi;Hu Tingting;Qu Xiaoyu;Zhai Jinghui;Zhang Yueming;Tao Lina;Yin Jianyuan;Song Yanqing
3 Prophylactic Therapy of Silymarin (Milk Thistle) on Antituberculosis Drug-Induced Liver Injury: A Meta-Analysis of Randomized Controlled Trials 期刊论文 Tao Lina;Qu Xiaoyu;Zhang Yue;Song Yanqing;Zhang Si xi
4 XingNaoJing injections protect against cerebral ischemia/reperfusion injury and alleviate blood-brain barrier disruption in rats, through an underlying mechanism of NLRP3 inflammasomes suppression 期刊论文 Qu Xiao-Yu;Zhang Yue-Ming;Tao Li-Na;Gao Huan;Zhai Jing-Hui;Sun Jing-Meng;Song Yan-Qing;Zhang Si-Xi
5 Astragaloside IV protects against cisplatin-induced liver and kidney injury via autophagy-mediated inhibition of NLRP3 in rats 期刊论文 Qu Xiaoyu;Gao Huan;Tao Lina;Zhang Yueming;Zhai Jinghui;Sun Jingmeng;Song Yanqing;Zhang Sixi
6 Dioscorea bulbifera L. delays the excretion of doxorubicin and aggravates doxorubicin-induced cardiotoxicity and nephrotoxicity by inhibiting the expression of P-glycoprotein in mice liver and kidney 期刊论文 Qu Xiaoyu;Zhai Jinghui;Hu Tingting;Gao Huan;Tao Lina;Zhang Yueming;Song Yanqing;Zhang Sixi
7 参百益通过诱导自噬和抑制NLRP3炎症小体保护顺铂诱导的HK-2细胞损伤 期刊论文 翟婧卉;曲晓宇;王力可;宋燕青
8 Calycosin ameliorates doxorubicin-induced cardiotoxicity by suppressing oxidative stress and inflammation via the sirtuin 1-NOD-like receptor protein 3 pathway 期刊论文 Zhai Jinghui;Tao Lina;Zhang Sixi;Gao Huan;Zhang Yueming;Sun Jingmeng;Song Yanqing;Qu Xiaoyu
9 Quercetin protected against isoniazide-induced HepG2 cell apoptosis by activating the SIRT1/ERK pathway 期刊论文 Zhang Yueming;Zhang Wenrui;Tao Lina;Zhai Jinghui;Gao Huan;Song Yanqing;Qu Xiaoyu
10 黄芪甲苷经FXR-NLRP3途径保护顺铂诱导的小鼠肾损伤研究 期刊论文 巩佳威;宋燕青;高欢;曲晓宇
11 Altered metabolic profiles and biomarkers associated with astragaloside IV-mediated protection against cisplatin-induced acute kidney injury in rats: an HPLC-TOF/MS-based untargeted metabolomics study 期刊论文 Yanqing Song;Tingting Hu;Huan Gao;Jinghui Zhai;Jiawei Gong;Yueming Zhang;Lina Tao;Jingmeng Sun;Zhiyuan Li;Xiaoyu Qu
12 Autophagy inhibition-enhanced assembly of the NLRP3 inflammasome is associated with cisplatin-induced acute injury to the liver and kidneys in rats 期刊论文 Qu Xiaoyu;Gao Huan;Tao Lina;Zhang Yueming;Zhai Jinghui;Song Yanqing;Zhang Sixi
13 Salvianolic acid inhibits the effects of high glucose on vascular endothelial dysfunction by modulating the Sirt1-eNOS pathway 期刊论文 Zhai Jinghui;Qu Xiaoyu;Zhang Yueming;Gao Huan;Tao Lina;Song Yanqing;Zhang Sixi
14 水飞蓟制剂预防性治疗抗结核药物性肝损伤效果的Meta分析 期刊论文 陶娌娜;曲晓宇;张越;宋燕青;张四喜
15 Identification of key metabolites during cisplatin-induced acute kidney injury using an HPLC-TOF/MS-based non-targeted urine and kidney metabolomics approach in rats 期刊论文 Qu Xiaoyu;Gao Huan;Sun Jingmeng;Tao Lina;Zhang Yueming;Zhai Jinghui;Song Yanqing;Hu Tingting;Li Zhiyuan
16 Astragaloside IV enhances cisplatin chemosensitivity in hepatocellular carcinoma by suppressing MRP2 期刊论文 Qu Xiaoyu;Gao Huan;Zhai Jinghui;Sun Jingmeng;Tao Lina;Zhang Yueming;Song Yanqing;Hu Tingting
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享