天然小分子化合物NAB01-10阻断视神经脊髓炎NMO-IgG与AQP4结合及神经保护作用的分子机制研究
81771304
2017
H0907.神经系统免疫异常及相关疾病
李淼
面上项目
教授
吉林大学
54万元
高通量筛选;视神经脊髓炎;水通道蛋白4;药物联合应用;天然小分子化合物
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 水通道蛋白4小分子抑制剂的筛选和验证 | 期刊论文 | 王楠;郭健;闫冰;刘晴;张磊;许会静;李淼;孙美艳 |
| 2 | Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo | 期刊论文 | Wang Jie;Liang Huaxin;Sun Meiyan;Zhang Lei;Xu Huijing;Liu Wei;Li Yan;Zhou Yue;Li Yingya;Li Miao |
| 3 | Combination of immune checkpoint inhibitors with chemotherapy in lung cancer | 期刊论文 | Liu Wei;Zhang Lei;Xiu Zhiming;Guo Jian;Wang Liye;Zhou Yue;Jiao Yang;Sun Meiyan;Cai Jianhui |
| 4 | A brief review of nutraceutical ingredients in gastrointestinal disorders: Evidence and suggestions | 期刊论文 | Gao Xiang;Liu Jingwen;Li Li;Liu Wei;Sun Meiyan |
| 5 | Nitric oxide (NO) and NO synthases (NOS)-based targeted therapy for colon cancer | 期刊论文 | Wang Hao;Wang Liye;Xie Zuoxu;Zhou Shuang;Li Yan;Zhou Yue;Sun Meiyan |
| 6 | The Anti-Inflammatory Effects of Vitamin D in Tumorigenesis | 期刊论文 | Wei Liu;Lei Zhang;Hui-Jing Xu;Yan Li;Chuan-Min Hu;Jing-Yan Yang;Mei-Yan Sun |
| 7 | Characterization and therapeutic applications of mesenchymal stem cells for regenerative medicine | 期刊论文 | Jie Wang;Zhuo Chen;Meiyan Sun;Huijing Xu;Yufei Gao;Jingwen Liu;Miao Li |
| 8 | Stem Cell-Based Therapies for Liver Diseases: An Overview and Update | 期刊论文 | Wang Jie;Sun Meiyan;Liu Wei;Li Yan;Li Miao |
| 9 | Identification of geraldol as an inhibitor of aquaporin-4 binding by NMO-IgG | 期刊论文 | Wang Jie;Wang Shuai;Sun Meiyan;Xu Huijing;Liu Wei;Wang Deli;Zhang Lei;Li Yan;Cao Jiaming;Li Fang;Li Miao |
| 10 | ANO7: Insights into topology, function, and potential applications as a biomarker and immunotherapy target | 期刊论文 | Guo Jian;Wang Dan;Dong Yuan;Gao Xiang;Tong Haibin;Liu Wei;Zhang Lei;Sun Meiyan |
| 11 | 用于治疗视神经脊髓炎的小分子化合物及其高通量筛选方法 | 专利 | 孙美艳;许会静;王捷;李淼;李艳;郝峰;张磊;姜勇;侯毅鞠;孟桂先;李明光 |
| 12 | AQP4真核表达载体的构建和AQP4-M23蛋白在中国仓鼠肺细胞系V79中的表达 | 期刊论文 | 许会静;刘晴;闫冰;刘微;张磊;郭健;姜琳;李淼;孙美艳;李艳 |
| 13 | Recent Insights Into the Prognostic and Therapeutic Applications of Lysozymes | 期刊论文 | Jiang Lin;Li Yunhe;Wang Liye;Guo Jian;Liu Wei;Meng Guixian;Zhang Lei;Li Miao;Cong Lina;Sun Meiyan |
| 14 | 一种用于治疗视神经脊髓炎的中药组合物及其制备方法和应用 | 专利 | 孙美艳;许会静;刘微;张磊;姜琳;李淼;王捷;王皓;闫冰;刘晴 |
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