基于皮肤代谢和信号通路分析探究多柔比星脂质体诱发HFS不良反应的作用机制

81673502
2016
H3510.药物代谢与药物动力学
李全顺
面上项目
教授
吉林大学
65万元
信号通路;代谢组学;代谢特征;手足综合征;多柔比星脂质体
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A comprehensive review on histone-mediated transfection for gene therapy 期刊论文 Haobo Han;Jiebing Yang;Wenqi Chen;Qing Li;Yan Yang;Quanshun Li
2 Immobilized lipase in bio-based metal-organic frameworks constructed by biomimetic mineralization: a sustainable biocatalyst for biodiesel synthesis 期刊论文 Qing Li;Yingxuan Chen;Shaowei Bai;Xinxin Shao;Lin Jiang;Quanshun Li
3 Inhibition of cell proliferation through an ATP-responsive co-delivery system of doxorubicin and Bcl-2 siRNA 期刊论文 Jianxu Zhang;Yudi Wang;Jiawen Chen;Xiao Liang;Hanbo Han;Yan Yang;Quanshun Li;Yanbo Wang
4 Determination of rabeprazole enantiomers in dog plasma by supercritical fluid chromatography tandem mass spectrometry and its application to a pharmacokinetic study 期刊论文 Chong Su;Hong Yang;Xiangjun Meng;J. Paul Fawcett;Jianmin Cao;Yan Yang;Jingkai Gu
5 N-Isopropylacrylamide-modified polyethylenimine-mediated miR-29a delivery to inhibit the proliferation and migration of lung cancer cells 期刊论文 Jiakai Xing;Jiaxin Jia;Xiaofeng Cong;Ziling Liu;Quanshun Li
6 Enantio-, regio-, and chemoselective lipase-catalyzed polymer synthesis 期刊论文 Jiebing Yang;Yong Liu;Xiao Liang;Yan Yang;Quanshun Li
7 Phenylboronic acid-modified polyamidoamine-mediated delivery of short GC rich DNA for hepatocarcinoma gene therapy 期刊论文 Jiebing Yang;Jiayuan Zhang;Yong Liu;Zhiyuan Shi;Haobo Han;Quanshun Li
8 Nano-scaled zeolitic imidazole framework-8 as an efficient carrier for the intracellular delivery of RNase A in cancer treatment 期刊论文 Jiaxin Jia;Shudi Zhang;Kai Wen;Quanshun Li
9 2-Amino-6-chloropurine-modified polyamidoamine-mediated p53 gene transfection to achieve anti-tumor efficacy 期刊论文 Haobo Han;Wenqi Chen;Jiebing Yang;Jiayuan Zhang;Quanshun Li;Yan Yang
10 Phenylboronic acid-functionalized polyamidoamine-mediated miR-34a delivery for the treatment of gastric cancer 期刊论文 Zheyu Song;Xiao Liang;Yudi Wang;Haobo Han;Jiebing Yang;Xeudong Fang;Quanshun Li
11 Nucleobase-modified polyamidoamine-mediated miR-23b delivery to inhibit the proliferation and migration of lung cancer 期刊论文 Haobo Han;Jiebing Yang;Yudi Wang;Wenqi Chen;Jiawen Chen;Yan Yang;Quanshun Li
12 Immobilization of urease in metal-organic frameworks via biomimetic mineralization and its application in urea degradation 期刊论文 Xiao Liang;Qing Li;Zhiyuan Shi;Shaowei Bai;Quanshun Li
13 Inhibition of proliferation and migration of tumor cells through phenylboronic acid-functionalized polyamidoamine-mediated delivery of a therapeutic DNAzyme Dz13 期刊论文 Jiebing Yang;Jiayuan Zhang;Jiakai Xing;Zhiyuan Shi;Haobo Han;Quanshun Li
14 An ATP-responsive codelivery system of doxorubicin and miR-34a to synergistically inhibit cell proliferation and migration 期刊论文 Yudi Wang;Jiawen Chen;Xiao Liang;Haobo Han;Hao Wang;Yan Yang;Quanshun Li
15 Inhibition of proliferation and migration of tumor cells through lipoic acid-modified oligoethylenimine-mediated p53 gene delivery 期刊论文 Xiuhui Tang;Qing Li;Xiao Liang;Jiebing Yang;Ziling Liu;Quanshun Li
16 Reactive oxygen species-mediated inflammation and apoptosis in hand-foot syndrome induced by PEGylated liposomal doxorubicin 期刊论文 Xiaolin Hu;Mengmeng Dong;Xiao Liang;Ziling Liu;Quanshun Li
17 Development and application of an MSALL-based approach for the quantitative analysis of linear polyethylene glycols in rat plasma by liquid chromatography triple-Quadrupole/Time-of-Flight mass spectrometry 期刊论文 Xiaotong Zhou;Xiangjun Meng;Longmei Cheng;Chong Su;Yantong Sun;Lingxia Sun;Zhaohui Tang;John Paul Fawcett;Yan Yang;Jingkai Gu
18 Immobilization of thermophilic lipase in inorganic hybrid nanoflower through biomimetic mineralization 期刊论文 Yong Liu;Xinxin Shao;Deqiang Kong;Guangquan Li;Quanshun Li
19 Inhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery 期刊论文 Haobo Han;Wenqi Chen;Jiebing Yang;Xiao Liang;Yudi Wang;Quanshun Li;Yan Yang;Kun Li
20 Differential mobility spectrometry tandem mass spectrometry with multiple ion monitoring for the bioanalysis of liraglutide 期刊论文 Xiangjun Meng;Haitong Xu;Zhi Zhang;John Paul Fawcett;Junru Li;Yan Yang;Jingkai Gu
21 Chemoenzymatic synthesis of a cholesterol-g-poly(amine-co-ester) carrier for p53 gene delivery to inhibit the proliferation and migration of tumor cells 期刊论文 Mengmeng Dong;Jiawen Chen;Jiebing Yang;Wei Jiang;Haobo Han;Quanshun Li;Yan Yang
22 Inhibition of cancer cell proliferation by adenosine triphosphate-triggered codelivery system of p53 gene and doxorubicin 期刊论文 Yong Liu;Xinxin Shao;Zhiyuan Shi;Quanshun Li
23 A chemoenzymatically synthesized cholesterol-g-poly(amine-co-ester)-mediated p53 gene delivery for achieving antitumor efficacy in prostate cancer 期刊论文 Mengmeng Dong;Jiawen Chen;Jiayuan Zhang;Xiao Liang;Jiebing Yang;Dan Li;Quanshun Li
24 A genipin-crosslinked protein-polymer hybrid system for the intracellular delivery of ribonuclease A 期刊论文 Xiao Liang;Xiuhui Tang;Jiebing Yang;Jiayuan Zhang;Haobo Han;Quanshun Li
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