基于诱导ES细胞定向分化的化合物库构建和信号转导分子事件发现

90813026
2008
H3401.合成药物化学
俞永平
重大研究计划
教授
浙江大学
60万元
signal;event;embryonic;small;protein;cell;chemistry;prenylation.;stem;combinatorial;probe;transduction;molecule
2009-01-01到2011-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Embryonic stem cell application in drug discovery 期刊论文 Lou Yijia |Liang Xingguang |
2 Skeletal muscle aldolase A overexpressed in endotoxemic rats and Inhibited by GSNO via potential role for S-nitrosylation in vitro 期刊论文 Chen Zhe |Shi Qiang |Zhu Danyan |Zhuang Renyao |Lou Yijia |Yan Jieping|
3 Metal-free carbon–nitrogen bond-forming coupling reaction between arylboronic acids and organic azides 期刊论文 Ou Lili|Shao Jiaan |Yu Yongping |Zhang Guolin |
4 Promoting effects of isobavachin on neurogenesis of mouse embryonic stem cells were associated with protein prenylation 期刊论文 Wang Danyin |Lou Yijia |Zhu Danyan |Hu Yuzhe |Yu Yongping |Kong Sisi |
5 Anti-tumor effects of a novel quinazoline derivative called B-2 on the human lung adenocarcinoma A549 cell line in vitro and in vivo 期刊论文 Yu Yongping |Chen Zhe |Yang Yuhong|Zhang Yandong |Ye Ziqi |Gao Lingyan |Lou Yijia |Huang Xin |Ding Wenbo |
6 Domino Approach for the Synthesis of Pyrrolo[1,2-alpha]pyrazine from Vinyl Azides 期刊论文 Chen, Wenteng|Wu, Jianwei|Yu, Yongping|Hu, Miao|Zou, Hongbin|
7 Solid-phase synthesis of skeletally diverse benzofused sultams via palladium-catalyzed cyclization 期刊论文 Chen Wenteng|Ou Lili |Giulianott Marc A. |Houghten Richard A. |Yu Yongping |Li Zhi|
8 Solid-phase synthesis of 2,3,5,6-tetrahydro-1H-imidazo[1,2-a]benzo[d]-[1,3]diazepines via Pd(OAc)2/Cu(OAc)2-cocatalyzed cyclization 期刊论文 Giulianotti Marc A. |Houghten Richard A. |Shao Zhanying|Ou Lili |Yu Yongping |Chen Wenteng |
9 Synthesis of Polysubstituted 5-Aminooxazoles from alpha- Diazocarbonyl Esters and alpha-Isocyanoacetamides 期刊论文 Chen, Wenteng|Zou, Hongbin|Hu, Miao|Yu, Yongping|Wu, Jianwei|
10 Enhanced co-expression of beta-tubulin III and choline acetyltransferase in neurons from mouse embryonic stem cells promoted by icaritin in an estrogen receptor-independent manner 期刊论文 Yu, Yongping|lou, Yijia|Wu, Jiaying|Zhang, Xiangnan|Wang, Huanhuan|Zhu, Danyan|Wang, Zhiqiang|Ou, Lili|
11 Synthesis and Antitumor Evaluation of a Novel Class of 4-Substituted-1,4-Dihydroisoquinolin-3-ones 期刊论文 Chen, Wenteng|Ma, Ting|Zhang, Guolin|Yu, Yongping|
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