胆碱能M3受体拮抗剂和抗癌药靶器官给药协同抗肺癌EMT途径的免疫机制
82003760
2020
H3504.抗炎与免疫药物药理
沈辉娟
青年科学基金项目
主管药师
浙江大学
24万元
原位腺癌模型;小分子抗肿瘤药;吸入给药;上皮间质转化;胆碱能M3受体拮抗剂
2021-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Single-cell transcriptomic characterization reveals the landscape of airway remodeling and inflammation in a cynomolgus monkey model of asthma | 期刊论文 | Yingshuo Wang;Xinyan Dong;Caizhe Pan;Cihang Zhu;Hantao Qi;Yifan Wang;Hao Wei;Qiangmin Xie;Lei Wu;Huijuan Shen;Shuxian Li;Yicheng Xie |
| 2 | Glycopyrronium bromide regulates cigarette smoke-induced epithelial mesenchymal transition by mediating ACh production | 期刊论文 | Huijuan Shen;Junxia Jiang;Hongyi Yao;Haiyun Zhou;Qiangmin Xie;Haibin Dai;Xile Zhou |
| 3 | Effects of 101BHG-D01, a novel M receptor antagonism, on allergic rhinitis in animal models and its mechanism | 期刊论文 | Huijuan Shen;Hao Wei;Junxia Jiang;Hongyi Yao;Yongliang Jia;Jian Shen;Yanyou Li;Qiangmin Xie;Xiaoping Chen;Yicheng Xie;Haibin Dai |
| 4 | Inhalation of panaxadiol alleviates lung inflammation via inhibiting TNFA/TNFAR and IL7/IL7R signaling between macrophages and epithelial cells | 期刊论文 | Yifan Wang;Hao Wei;Zhen Song;Liqun Jiang;Mi Zhang;Xiao Lu;Wei Li;Yuqing Zhao;Lei Wu;Shuxian Li;Huijuan Shen;Qiang Shu;Yicheng Xie |
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