解析GBM基于EGFR/PI3K信号通路多模式靶向治疗靶标的研究

30772238
2007
H1815.肿瘤靶向治疗
任欢
面上项目
教授
哈尔滨医科大学
28万元
信号转导通路;靶标;靶向治疗;EGFR;脑胶质母细胞瘤（GBM）
2008-01-01到2010-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 解析恶性胶质瘤基于EGFR/PI3K信号转导通路多模式靶向治疗靶标的研究 会议论文 任欢|
2 siRNA靶向抑制PDGFRB对人恶性脑胶质瘤细胞增殖的抑制作用 期刊论文 官杰|赵立飞|彭相文|董裕翠|任欢|谭小青|
3 脑肿瘤的化学治疗 专著 史卫忠|王永志|李少武|李红霞|林志雄|高之宪|贺罡|黄强|韩容|陈宝师|魏新亭|江涛|平轶芳|李志伟|邓宁|张艳桥|周建华|董军|林毅|任欢|卞修武|徐丽|蒋传路|陆海波|李守巍|杨学军|张伟|王斌|周开甲|游赣|王国成|甲戈|赵志刚|马文斌|程化坤|
4 Receptor Tyrosine Kinases as therapeutic targets in malignant glioma- current status and application in China 会议论文 任欢|
5 Imatinib对恶性脑胶质瘤细胞PDGFR下游信号传导通路作用的研究 会议论文 任欢|
6 Recurrent glioblastoma of childhood treated with bevacizumab: case report and molecular features. 期刊论文 Chen Baoshi|Song Songya Wei|Jiang Tao|Zhang Wei|Lin Yi|
7 Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells 期刊论文 Lan Fengming|Yang Weidong|Jiang Tao|Zhang Anling|Yue Xiao|Yang Yang|Liu Jilong|Zeng Huazong|Han Lei|
8 Prognostic factors influencing clinical outcomes of glioblastoma multiforme 期刊论文 Wang Zhongcheng|Jiang Tao|Li Shouwei|Ren Huan|Chen Baoshi|Qiu Xiaoguang|Zhang Wei|
9 Differential effect of imatinib and synergism of combination treatment with chemotherapeutic agents in malignant glioma cells 期刊论文 Ren Huan|Rainov Nikolai|Chou Tingchao|Tan Xiaoqing|Dong Yucui|Yang Baofeng|Giese Alf|
10 Selective inhibition on PDGFR by imatinib elicits sustained activation of ERK and downstream receptor signaling in malignant glioma cells 期刊论文 Deng Zhenling|Li Baoxin|Dong Yucui|Xu Jiankai|Jia Limin|Tan Xiaoqing|Ren Huan|Jiang Tao|Wang Xiaohua|Rainov Nikolai G|
11 Antiangiogenic therapy with bevacizumab in recurrent malignant gliomas: analysis of the response and core pathway aberrations 期刊论文 Li Shouwei|Cui Yun|Qiu Xiaoguang|Zhang Wei|Chen Baoshi|Ren Huan|Jiang Tao|
12 Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas 期刊论文 Qiu Xiaoguang|Chen Baoshi|Song Sonya W|Zhang Wei|Zhou Kaijia|Lin Yi|Jiang Tianzi|Li Guilin|Xu Li|Jiang Tao|
13 A sub-pathway-based approach for identifying drug response principal network 期刊论文 XU J|Wu X|Liu L|Li X|Li J|Ma L|Bian X |Huang B|Chen S|Tan F|Chen X|Jia X|
14 Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription 期刊论文 Yue Xiao|Liu Xiaomin|Pu Peiyu|Yang Yang|Jiang Tao|Han Lei|Huang Kai|Jiang Hao|Kang Chunsheng|Yan Wei|
15 抗血管生成靶向药物治疗恶性胶质瘤的临床研究 期刊论文 张忠|张伟|李守巍|江涛|陈宝师|
16 以表皮生长因子受体为靶点恶性脑胶质瘤靶向治疗研究进展 期刊论文 董裕翠|赵立飞|任欢|
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