基于GSA/SGLT1研究墨角藻多糖FVF抑制餐后高血糖的分子机制及其对肠道菌群影响

31670811
2016
C0506.糖、脂生物化学
于广利
面上项目
教授
中国海洋大学
65万元
制备;活性多糖;多糖结构;调控机制;构效关系
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulation 期刊论文 Li Qinying;Cai Chao;Chang Yaoguang;Zhang Fuming;Linhardt Robert J;Xue Changhu;Li Guoyun;Yu Guangli
2 Marine polysaccharides attenuate metabolic syndrome by fermentation products and altering gut microbiota: An overview 期刊论文 Wang Xueliang;Wang Xin;Jiang Hao;Cai Chao;Li Guoyun;Hao Jiejie;Yu Guangli
3 Carbohydrate microarray-based analysis of specific interactions between saccharides from algin and influenza A viral hemagglutinin 期刊论文 Liu Chanjuan;Li Chao;Li Guoyun;Yu Guangli
4 Two different fucosylated chondroitin sulfates: Structural elucidation, stimulating hematopoiesis and immune-enhancing effects 期刊论文 Niu Qingfeng;Li Guoyun;Li Chao;Li Qinying;Li Jia;Liu Chanjuan;Pan Lin;Li Shijie;Cai Chao;Hao JieJie;Yu Guangli
5 Gut microbiota fermentation of marine polysaccharides and its effects on intestinal ecology: An overview 期刊论文 Shang Qingsen;Jiang Hao;Cai Chao;Hao Jiejie;Li Guoyun;Yu Guangli
6 一种具有促进伤口愈合作用的糖类组合物及其应用 专利 于广利;丁琅;赵小亮;单鑫迪;郝杰杰;蔡超;李国云
7 海洋褐藻多糖的质量控制技术和药用生物活性研究 奖励 赵峡;于广利;郝杰杰;李春霞;王伟;管华诗
8 Fabrication of carbohydrate microarrays on poly(2-hydroxyethyl methacrylate)-cyanuric chloride-modified substrates for the analysis of carbohydrate-lectin interactions 期刊论文 Liu Chanjuan;Li Chao;Niu Qingfeng;Cai Chao;Li Guoyun;Yu Guangli
9 一种带有聚合物骨架的糖芯片及其制备方法与应用 专利 刘婵娟;于广利;李国云;李超
10 Structural Characterization and Interaction with RCA(120) of a Highly Sulfated Keratan Sulfate from Blue Shark (Prionace glauca) Cartilage 期刊论文 Li Qinying;Li Guoyun;Zhao Xiaoliang;Shan Xindi;Cai Chao;Zhao Jing;Zhang Fuming;Linhardt Robert J;Yu Guangli
11 Dietary Polysaccharide from Enteromorpha Clathrata Modulates Gut Microbiota and Promotes the Growth of Akkermansia muciniphila, Bifidobacterium spp. and Lactobacillus spp. 期刊论文 Shang Qingsen;Wang Ya;Pan Lin;Niu Qingfeng;Li Chao;Jiang Hao;Cai Chao;Hao Jiejie;Li Guoyun;Yu Guangli
12 Inhibition of Influenza A Virus Infection by Fucoidan Targeting Viral Neuraminidase and Cellular EGFR Pathway 期刊论文 Wang Wei;Wu Jiandong;Zhang Xiaoshuang;Hao Cui;Zhao Xiaoliang;Jiao Guangling;Shan Xindi;Tai Wenjing;Yu Guangli
13 Odd-numbered agaro-oligosaccharides alleviate type 2 diabetes mellitus and related colonic microbiota dysbiosis in mice 期刊论文 Wang Xueliang;Yang Zimei;Xu Xu;Jiang Hao;Cai Chao;Yu Guangli
14 Synthesis and Properties of Functional Glycomimetics through Click Grafting of Fucose onto Chondroitin Sulfates 期刊论文 Fan Fei;Zhang Ping;Wang Lihao;Sun Tiantian;Cai Chao;Yu Guangli
15 Degradation of Marine Algae-Derived Carbohydrates by Bacteroidetes Isolated from Human Gut Microbiota 期刊论文 Li Miaomiao;Shang Qingsen;Li Guangsheng;Wang Xin;Yu Guangli
16 Fucoidan fromAscophyllumnodosumSuppresses Postprandial Hyperglycemia by Inhibiting Na+/Glucose Cotransporter 1 Activity 期刊论文 Shan Xindi;Wang Xueliang;Jiang Hao;Cai Chao;Hao Jiejie;Yu Guangli
17 Dietary fucoidan improves metabolic syndrome in association with increased Akkermansia population in the gut microbiota of high-fat diet-fed mice 期刊论文 Shang Qingsen;Song Guanrui;Zhang Meifang;Shi Jingjing;Xu Cuiying;Hao Jiejie;Li Guoyun;Yu Guangli
18 Structure and immunomodulatory activity of a sulfated agarose with pyruvate and xylose substitutes from Polysiphonia senticulosa Harvey 期刊论文 Zhao Xiaoliang;Jiao Guangling;Yang Yi;Li Miaomiao;Li Qinying;Wang Xiaojiang;Cai Chao;Li Guoyun;Hao Jiejie;Yu Guangli
19 Anti-diabetic activities of agaropectin-derived oligosaccharides from Gloiopeltis furcata via regulation of mitochondrial function 期刊论文 Wang Xueliang;Jiang Hao;Zhang Ning;Cai Chao;Li Guoyun;Hao Jiejie;Yu Guangli
20 Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling 期刊论文 Wang Xueliang;Shan Xindi;Dun Yunlou;Cai Chao;Hao Jiejie;Li Guoyun;Cui Kaiyun;Yu Guangli
21 Dietary Keratan Sulfate from Shark Cartilage Modulates Gut Microbiota and Increases the Abundance of Lactobacillus spp. 期刊论文 Shang Qingsen;Li Qinying;Zhang Meifang;Song Guanrui;Shi Jingjing;Jiang Hao;Cai Chao;Hao Jiejie;Li Guoyun;Yu Guangli
22 Structural characterization and anti-thrombotic properties of fucoidan from Nemacystus decipiens. 期刊论文 Cui K;Tai W;Shan X;Hao J;Li G;Yu G
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