基于新生大鼠脑瘫模型的六味地黄丸治疗五迟、五软证的作用机理及药效物质基础研究

81473584
2014
H3105.中医方剂学
王萍
面上项目
研究员
黑龙江中医药大学
74万元
实验研究;作用机理;代谢组学;药效物质基础;方剂配伍
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 基于中医方证代谢组学技术的六味地黄丸干预脑瘫大鼠模型研究 期刊论文 李秋菊;王萍;王美佳;康舒宇;张也;张爱华;王喜军
2 基于整合药理学的中药现代研究进展 期刊论文 王萍;唐仕欢;苏瑾;张佳琪;崔如意;许海玉;杨洪军
3 基于整合药理学平台的六味地黄丸治疗糖尿病的分子机制研究 期刊论文 张 佳 琪;唐 仕 欢;李 德 凤;张 毅;苏 瑾;刘 杨;张 艾 嘉;王 萍;王喜军
4 Scoparone affects lipid metabolism in primary hepatocytes using lipidomics 期刊论文 Aihua Zhang;Shi Qiu;Hui Sun;Tianlei Zhang;Yu Guan;Ying Han;Guangli Yan;Xijun Wang
5 Insight into the metabolic mechanism of scoparone on biomarkers for inhibiting Yanghuang syndrome 期刊论文 Heng Fang;Aihua Zhang;Jingbo Yu;Liang Wang;Chang Liu;Xiaohang Zhou;Hui Sun;Qi Song;Xijun Wang
6 Rapid discovery of quality-markers from Kaixin San using chinmedomics analysis approach 期刊论文 Xijun Wang;Aihua Zhang;Ling Kong;Jingbo Yu;Honglei Gao;Zhidong Liu;Hui Sun
7 基于尿液代谢组学的六味地黄丸对大鼠生长发育的影响 期刊论文 康舒宇;张佳琪;张艾嘉;王萍;王喜军
8 Prediction of the Pharmacokinetics of Traditional Chinese Medical Preparations based on Evaluating Constituent Pharmacokinetics, Structural Similarity, and Mathematical Modeling. 期刊论文 Ping Wang;Ke Li;Ye Tao;Defeng Li;Yi Zhang;Haiyu Xu;Hongjun Yang
9 Poly-pharmacokinetic strategy-delineated metabolic fate of bioactive T compounds in a traditional Chinese medicine formula, Yuanhu Zhitong tablets, using parallel reaction monitoring mode 期刊论文 Ping Wang;Tinglan Zhang;Guohua Yu;Mengjie Li;Jin Su;Jiaqi Zhang;Ke Li;Yan Fu;Haiyu Xu;Hongjun Yang
10 Recent advances and effective strategies in the discovery and applications of natural products 期刊论文 Jing Xie;Ai-hua Zhang;Hui Sun;Guang-li Yan;Xi-jun Wang
11 Metabolomics Deciphering Therapeutic Effects and Mechanism of Traditional Chinese Medicines 期刊论文 Weiwei Ma;Aihua Zhang;Hui Sun;Xiangcai Meng;Xijun Wang
12 Rapid discovery of absorbed constituents and metabolites in rat plasma after the oral administration of Zi Shen Wan using high‐throughput UHPLC–MS with a multivariate analysis approach 期刊论文 Xian-Na Li;Aihua Zhang;Hui Sun;Yanhua Song;Di Zou;Xijun Wang
13 基于数据挖掘的肾阴虚型消渴病方剂用药规律分析 期刊论文 王烨燃;张 洋;秦琦冰;王萍;谭 龙
14 Metabolomics and proteomics technologies to explore the herbal preparation affecting metabolic disorders using high resolution mass spectrometry 期刊论文 Aihua Zhang;Xiaohang Zhou;Hongwei Zhao;Shiyu Zou;Chung Wah Ma;Qi Liu;Hui Sun;Liang Liu;Xijun Wang
15 High-throughput chinmedomics- based prediction of effective components and targets from herbal medicine AS1350 期刊论文 Qi Liu;Aihua Zhang;Liang Wang;Guangli Yan;Hongwei Zhao;Hui Sun;Shiyu Zou;Jinwei Han;Chung Wah Ma;Ling Kong;Xiaohang Zhou;Yang Nan;Xijun Wang
16 六味地黄丸对大鼠生长发育过程中血液代谢的影响 期刊论文 康舒宇;张艾嘉;张佳琪;王萍;王喜军
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