羊栖菜岩藻聚糖硫酸酯靶向激活Nrf2-Keap1-ARE信号通路改善胰岛素抵抗的结构基础及机制研究

41876197
2018
D0604.生物海洋学与海洋生物资源
吴明江
面上项目
教授
温州大学
62万元
胰岛素抵抗;羊栖菜;岩藻聚糖硫酸酯;抗氧化;构效关系
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Sargassum fusiforme Alginate Relieves Hyperglycemia and Modulates Intestinal Microbiota and Metabolites in Type 2 Diabetic Mice 期刊论文 Liu Jian;Wu Siya;Cheng Yang;Liu Qiuhui;Su Laijin;Yang Yue;Zhang Xu;Wu Mingjiang;Choi Jong-il;Tong Haibin
2 一种羊栖菜幼孢子体栽培的单位质量评价及差异比较方法 专利 林立东;吴明江;郑影
3 Sargassum fusiforme polysaccharide attenuates high-sugar-induced lipid accumulation in HepG2 cells and Drosophila melanogaster larvae 期刊论文 He Dan;Yan Liping;Zhang Jiaqi;Li Fang;Wu Yu;Su Laijin;Chen Peichao;Wu Mingjiang;Choi Jong-il;Tong Haibin
4 Optimization of Porphyran Extraction from Pyropia yezoensis by Response Surface Methodology and Its Lipid-Lowering Effects 期刊论文 He Dan;Yan Liping;Hu Yingxia;Wu Qifang;Wu Mingjiang;Choi Jong-il;Tong Haibin
5 一种低分子量条斑紫菜多糖的制备及其在抗人宫颈癌细胞肿瘤中的应用 专利 吴明江;何丹;佟海滨;张旭;崔鐘一;于萍
6 Ethanol extract of Sargarsum fusiforme alleviates HFD/STZ-induced hyperglycemia in association with modulation of gut microbiota and intestinal metabolites in type 2 diabetic mice 期刊论文 Wu Siya;Zuo Jihui;Cheng Yang;Zhang Ya;Zhang Zhongshan;Wu Mingjiang;Yang Yue;Tong Haibin
7 Different extraction methods bring about distinct physicochemical properties and antioxidant activities of Sargassum fusiforme fucoidans 期刊论文 Liu Jian;Wu Si-Ya;Chen Ling;Li Qiao-Juan;Shen Yi-Zhe;Jin Li;Zhang Xu;Chen Pei-Chao;Wu Ming-Jiang;Choi Jong-il;Tong Hai-Bin
8 Sargassum fusiforme fucoidan ameliorates diet-induced obesity through enhancing thermogenesis of adipose tissues and modulating gut microbiota 期刊论文 Jihui Zuo;Ya Zhang;Yu Wu;Jian Liu;Qifang Wu;Yizhe Shen;Li Jin;Mingjiang Wu;Zengling Ma;Haibin Tong
9 Sargassum fusiforme fucoidan modifies gut microbiota and intestinal metabolites during alleviation of hyperglycemia in type 2 diabetic mice dagger 期刊论文 Wu Qifang;Wu Siya;Cheng Yang;Zhang Zhongshan;Mao Genxiang;Li Shijun;Yang Yue;Zhang Xu;Wu Mingjiang;Tong Haibin
10 Structural characterization and antagonistic effect against P-selectin-mediated function of SFF-32, a fucoidan fraction from Sargassum fusiforme 期刊论文 Siya Wu;Jian Liu;Ya Zhang;Jianxi Song;Zhongshan Zhang;Yue Yang;Mingjiang Wu;Haibin Tong
11 天然活性成分挖掘与高效生物合成关键技术及应用 奖励 廖志勇;吴明江;杨海龙
12 Sargassum fusiforme Fucoidan Alleviates High-Fat Diet-Induced Obesity and Insulin Resistance Associated with the Improvement of Hepatic Oxidative Stress and Gut Microbiota Profile 期刊论文 Zhang Ya;Zuo Jihui;Yan Liping;Cheng Yang;Li Qiaojuan;Wu Siya;Chen Ling;Thring Ronald W.;Yang Yue;Gao Yitian;Wu Mingjiang;Tong Haibin
13 Sargassum fusiforme fucoidan alleviates diet-induced insulin resistance by inhibiting colon-derived ceramide biosynthesis 期刊论文 Zhang Ya;Liu Jian;Mao Genxiang;Zuo Jihui;Li Shijun;Yang Yue;Thring Ronald W.;Wu Mingjiang;Tong Haibin
14 Proteomic landscape of liver tissue in old male mice that are long-term treated with polysaccharides fromSargassum fusiforme 期刊论文 Chen Peichao;Zhang Ya;Xu Man;Chen Hongjun;Zou Huixi;Zhang Xu;Tong Haibin;You Cuiping;Wu Mingjiang
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