基于NF-KB信号通路的长白山药用植物紫穗槐活性成分抗炎机制研究

81360496
2013
H3504.抗炎与免疫药物药理
金学军
地区科学基金项目
教授
延边大学
45万元
amorfrutin;紫穗槐;抗炎;NF-KB
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1alpha via the mTOR/p70S6K/4E-BP1 and MAPK pathways. 期刊论文 Mi Chunliu;Ma Juan;Wang Ke Si;Zuo Hong Xiang;Wang Zhe;Li Ming Yue;Piao Lian Xun;Xu Guang Hua;Li Xuezheng;Quan Zhe Shan;Jin Xuejun
2 Baicalein inhibits TNF-alpha-induced NF-kappa B activation and expression of NF-kappa B-regulated target gene products 期刊论文 Li Junbo;Ma Juan;Wang Ke Si;Mi Chunliu;Wang Zhe;Piao Lian Xun;Xu Guang Hua;Li Xuezheng;Lee Jung Joon;Jin Xuejun
3 Imperatorin efficiently blocks TNF-alpha-mediated activation of ROS/PI3K/Akt/NF-kappaB pathway. 期刊论文 Wang Ke Si;Lv Ying;Wang Zhe;Ma Juan;Mi Chunliu;Li Xuezheng;Xu Guang Hua;Piao Lian Xun;Zheng Sheng Zhe;Jin Xuejun
4 药物作用靶点开发及长白山药用植物活性成分抗炎研究 奖励 金学军;马娟;韩立卓;李晶埈;米春柳
5 Blockade of TNF-alpha-induced NF-kappaB signaling pathway and anti-cancer therapeutic response of dihydrotanshinone I. 期刊论文 Wang Fei;Ma Juan;Wang Ke Si;Mi Chunliu;Lee Jung Joon;Jin Xuejun
6 Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1alpha signaling. 期刊论文 Li Ming Yue;Mi Chunliu;Wang Ke Si;Wang Zhe;Zuo Hong Xiang;Piao Lian Xun;Xu Guang Hua;Li Xuezheng;Ma Juan;Jin Xuejun
7 长白山天然药用植物活性单体抗癌作用机制研究 奖励 金学军;马娟;韩立卓;米春柳;石慧;李静;王飞;李晶埈
8 Chelidonine inhibits TNF-alpha-induced inflammation by suppressing the NF-kappaB pathways in HCT116 cells. 期刊论文 Zhang Zhi Hong;Mi Chunliu;Wang Ke Si;Wang Zhe;Li Ming Yue;Zuo Hong Xiang;Xu Guang Hua;Li Xuezheng;Piao Lian Xun;Ma Juan;Jin Xuejun
9 Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-alpha-Induced NF-kappaB Activation. 期刊论文 Wang Zhe;Li Ming Yue;Mi Chunliu;Wang Ke Si;Ma Juan;Jin Xuejun
10 Amorfrutin A inhibits TNF-alpha induced JAK/STAT signaling, cell survival and proliferation of human cancer cells. 期刊论文 Mi Chunliu;Ma Juan;Wang Ke Si;Wang Zhe;Li Ming Yue;Li Jun Bo;Li Xuezheng;Piao Lian Xun;Xu Guang Hua;Jin Xuejun
11 Kamebakaurin inhibits the expression of hypoxia-inducible factor-1alpha and its target genes to confer antitumor activity. 期刊论文 Wang Ke Si;Ma Juan;Mi Chunliu;Li Jing;Lee Jung Joon;Jin Xuejun
12 Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways 期刊论文 Juan Ma; Jing Li; Ke Si Wang; Chunliu Mi; Lian Xun Piao; Guang Hua Xu; Xuezheng Li; Jung Joon Lee; Xuejun Jin
13 Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9. 期刊论文 Mi Chunliu;Shi Hui;Ma Juan;Han Li Zhuo;Lee Jung Joon;Jin Xuejun
14 Dihydromyricetin suppresses TNF-alpha-induced NF-kappa B activation and target gene expression 期刊论文 Tang Nina;Ma Juan;Wang Ke Si;Mi Chunliu;Lv Ying;Piao Lian Xun;Xu Guang Hua;Li Xuezheng;Lee Jung Joon;Jin Xuejun
15 4 ',6-Dihydroxy-4-methoxyisoaurone Inhibits the HIF-1 alpha Pathway Through Inhibition of Akt/mTOR/p70S6K/4E-BP1 Phosphorylation 期刊论文 Mi Chunliu;Ma Juan;Shi Hui;Li Jing;Wang Fei;Lee Jung Joon;Jin Xuejun
16 Amorfrutin A inhibits TNF-alpha-induced NF-kappaB activation and NF-kappaB-regulated target gene products. 期刊论文 Shi Hui;Ma Juan;Mi Chunliu;Li Jing;Wang Fei;Lee Jung Joon;Jin Xuejun
17 4',6-Dihydroxy-4-methoxyisoaurone inhibits TNF-alpha-induced NF-kappaB activation and expressions of NF-kappaB-regulated target gene products. 期刊论文 Ma Juan;Mi Chunliu;Wang Ke Si;Lee Jung Joon;Jin Xuejun
18 Malloapelta B suppresses LPS-induced NF-kappaB activation and NF-kappaB-regulated target gene products. 期刊论文 Ma Juan;Shi Hui;Mi Chunliu;Li Hong Lan;Lee Jung Joon;Jin Xuejun
19 Artemisinin inhibits inflammatory response via regulating NF-kappaB and MAPK signaling pathways. 期刊论文 Wang Ke Si;Li Junbo;Wang Zhe;Mi Chunliu;Ma Juan;Piao Lian Xun;Xu Guang Hua;Li Xuezheng;Jin Xuejun
20 Zinc finger protein 91 (ZFP91) activates HIF-1alpha via NF-kappaB/p65 to promote proliferation and tumorigenesis of colon cancer. 期刊论文 Ma Juan;Mi Chunliu;Wang Ke Si;Lee Jung Joon;Jin Xuejun
21 Dihydrotanshinone I inhibits the translational expression of hypoxia-inducible factor-1alpha. 期刊论文 Li Jing;Mi Chunliu;Ma Juan;Wang Ke Si;Lee Jung Joon;Jin Xuejun
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