围产期奶牛能量负平衡引发胰岛素抵抗的分子机制
31472247
2014
C1809.临床兽医学
刘国文
面上项目
教授
吉林大学
88万元
分子机制;胰岛素抵抗;能量负平衡;围产期奶牛
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Nobiletin alleviates palmitic acid-induced NLRP3 inflammasome activation in a sirtuin 1-dependent manner in AML-12 cells | 期刊论文 | Peng Zhicheng;Li Xiaobing;Du Xiliang;Wang Zhe;Liu Guowen;Li Xinwei;Xing Dongmei;Li XW |
| 2 | 线粒体DNA检测试剂在诊断奶牛脂肪肝的应用 | 专利 | 李心慰;刘国文;杜希良 |
| 3 | Effects of insulin-like growth factor-1 on the assembly and secretion of very low-density lipoproteins in cow hepatocytes in vitro | 期刊论文 | Li Xinwei;Li Ying;Wu Dianjun;Liu Lei;Li Xiaobing;Wang Zhe;Liu Guowen;Guan Yuan;Deng Qinghua;Liu GW;Deng QH |
| 4 | 一种以荷叶为主要成分的防治围产期奶牛综合征的粉剂 | 专利 | 李心慰;刘国文;房志愿;李小兵;杜希良;史珍;王哲;马赫然 |
| 5 | Acetoacetate induces hepatocytes apoptosis by the ROS-mediated MAPKs pathway in ketotic cows | 期刊论文 | Du Xiliang;Shi Zhen;Peng Zhicheng;Zhao Chenxu;Zhang Yuming;Wang Zhe;Li Xiaobing;Liu Guowen;Li Xinwei;Liu GW;Li XW |
| 6 | Elevated Apoptosis in the Liver of Dairy Cows with Ketosis | 期刊论文 | Du Xiliang;Huang Dan;Peng Zhicheng;Zhao Chenxu;Zhang Yuming;Zhu Yiwei;Wang Zhe;Li Xinwei;Liu Guowen;Chen Liang;Li XW;Liu GW |
| 7 | Acetoacetic acid induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes. | 期刊论文 | Shi Xiaoxia;Li Dangdang;Deng Qinghua;Peng Zhicheng;Zhao Chenxu;Li Xiaobing;Wang Zhe;Li Xinwei;Liu Guowen |
| 8 | Perilipin 1 Mediates Lipid Metabolism Homeostasis and Inhibits Inflammatory Cytokine Synthesis in Bovine Adipocytes | 期刊论文 | Zhang Shiqi;Liu Guowen;Zhang Qiang;Xu Qiushi;Jia Hongdou;Li Xiaobing;Li Xinwei;Xu Chuang;Liu Lei;Li XB;Li XW |
| 9 | beta-Hydroxybutyrate induces bovine hepatocyte apoptosis via an ROS-p38 signaling pathway | 期刊论文 | Song Yuxiang;Li Na;Gu Jingmin;Fu Shoupeng;Peng Zhicheng;Zhao Chenxu;Zhang Yuming;Li Xiaobing;Wang Zhe;Li Xinwei;Liu Guowen;Li XW;Liu GW |
| 10 | miR181a特异性引物试剂在诊断奶牛脂肪肝的应用 | 专利 | 杜希良;李心慰;刘国文;彭志成;赵晨旭 |
| 11 | High levels of acetoacetate and glucose increase expression of cytokines in bovine hepatocytes, through activation of the NF-kappa B signalling pathway | 期刊论文 | Li Yu;Ding Hongyan;Wang Xichun;Wu Jinjie;Liu Lei;Huang Dan;Zhang Renhe;Guo Lihui;Wang Zhe;Li Xiaobing;Liu Guowen;Li Xinwei;Wu JJ;Liu GW;Li XW |
| 12 | Ultrasonographic findings in cows with left displacement of abomasum, before and after reposition surgery | 期刊论文 | Li Xin-Wei;Xu Qiu-Shi;Zhang Ren-He;Zhang Yu-Ming;Tian Yu;Zhang Min;Wang Zhe;Liu Guo-wen;Li Xiao-Bing;Yang Wei;Xia Cheng;Li Yu;Li XB |
| 13 | Upregulation of miR-181a impairs hepatic glucose and lipid homeostasis | 期刊论文 | Du Xiliang;Yang Yuchen;Peng Zhicheng;Zhang Min;Lei Lin;Gao Wenwen;Dong Yuhao;Shi Zhen;Sun Xudong;Wang Zhe;Li Xiaobing;Li Xinwei;Liu Guowen;Xu Chuang;Li XW;Liu GW |
| 14 | Adaptations of hepatic lipid metabolism and mitochondria in dairy cows with mild fatty liver | 期刊论文 | Du Xiliang;Shen Taiyu;Ye Qianqian;Shi Zhen;Fang Zhiyuan;Zhu Yiwei;Yang Yuchen;Peng Zhicheng;Zhao Chenxu;Lv Bin;Li Xiaobing;Liu Guowen;Li Xinwei;Wang Heyuan;Qin Xia;Xing Dongmei;Liu GW;Li XW |
| 15 | Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells | 期刊论文 | Lei Lin;Zhu Yiwei;Gao Wenwen;Du Xiliang;Zhang Min;Peng Zhicheng;Fu Shoupeng;Li Xiaobing;Zhe Wang;Li Xinwei;Liu Guowen;Li XW;Liu GW |
| 16 | NEFA-induced ROS impaired insulin signalling through the JNK and p38MAPK pathways in non-alcoholic steatohepatitis | 期刊论文 | Gao Wenwen;Du Xiliang;Lei Lin;Zhang Min;Wang Zhe;Li Xiaobing;Liu Guowen;Li Xinwei;Wang Heyuan;Liu GW;Li XW |
| 17 | Berberine Protects against NEFA-Induced Impairment of Mitochondrial Respiratory Chain Function and Insulin Signaling in Bovine Hepatocytes | 期刊论文 | Shi Zhen;Li Xiao-Bing;Peng Zhi-Cheng;Fu Shou-Peng;Zhao Chen-Xu;Du Xi-Liang;Fang Zhi-Yuan;Wang Zhe;Liu Guo-Wen;Li Xin-Wei;Liu GW;Li XW |
| 18 | Insulin suppresses the AMPK signaling pathway to regulate lipid metabolism in primary cultured hepatocytes of dairy cows | 期刊论文 | Li Xinwei;Don Jihong;Zhan Renhe;Huang Dan;Lei Lin;Wang Zhe;Liu Guowen;Li Xiaobing;Li Yu;Ding Hongyan;Li XB |
| 19 | Hepatic miR-125b inhibits insulin signaling pathway by targeting PIK3CD | 期刊论文 | Du Xiliang;Li Xiaobing;Zhang Min;Lei Lin;Gao Wenwen;Shi Zhen;Dong Yuhao;Wang Zhe;Li Xinwei;Liu Guowen;Chen Liang;Li XW;Liu GW |
| 20 | Impaired hepatic autophagic activity in dairy cows with severe fatty liver is associated with inflammation and reduced liver function | 期刊论文 | Du Xiliang;Liu Guowen;Fang Zhiyuan;Yang Yuchen;Ye Qianqian;Shi Zhen;Shen Taiyu;Wang Xinghui;Peng Zhicheng;Zhao Chenxu;Lv Bin;Zhu Yiwei;Li Xiaobing;Li Xinwei;Loor Juan J.;Bucktrout Ryan;Loor Juan J.;Bucktrout Ryan;Xing Dongmei;Li XW |
| 21 | High concentrations of fatty acids and beta-hydroxybutyrate impair the growth hormone-mediated hepatic JAK2-STAT5 pathway in clinically ketotic cows | 期刊论文 | Du Xiliang;Zhu Yiwei;Peng Zhicheng;Cui Yuanxu;Zhang Qiang;Shi Zhen;Guan Yuan;Sha Xueying;Shen Taiyu;Yang Yuchen;Li Xiaobing;Wang Zhe;Li Xinwei;Liu Guowen;Li XW;Liu GW |
| 22 | Effects of -hydroxybutyricacid on the synthesis and assembly of very low-density lipoprotein in bovine hepatocytes invitro | 期刊论文 | Deng Q.;Shi Z.;Huang W.;Du X.;Gao W.;Lei L.;Zhang M.;Li X.;Wang Z.;Liu G.;Li X.;Deng Q.;Ma D.;Sun G.;Yuan X.;Liu G.;Zhu X.;Zhu X.;Liu G;Li X |
| 23 | Histamine Induces Bovine Rumen Epithelial Cell Inflammatory Response via NF-kappa B Pathway | 期刊论文 | Sun Xudong;Wang Tingting;Wang Zhe;Li Xiaobing;Li Xinwei;Liu Guowen;Yuan Xue;Sun Guoquan;Chen Liang;Li XW;Liu GW |
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