HuR调控转录因子EB在骨性关节炎中的作用机制研究
81902243
2019
H0608.骨、关节、软组织退行性病变
潘宗友
青年科学基金项目
研究员
浙江大学
21万元
RNA结合蛋白HuR;骨性关节炎;氧化应激;自噬流;转录因子EB
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 20-Deoxyingenol alleviates osteoarthritis by activating TFEB in chondrocytes | 期刊论文 | Mingbao Gu;Jie Jin;Chenghao Ren;Ximiao Chen;Zongyou Pan;Yaosen Wu;Naifeng Tian;Liaojun Sun;Aimin Wu;Weiyang Gao;Yifei Zhou;Zhongke Lin;Xiaolei Zhang |
| 2 | Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages | 期刊论文 | Libin Ni;Zhen Lin;Sunli Hu;Yifeng Shi;Zhichen Jiang;Jiayi Zhao;Yifei Zhou;Yaosen Wu;Naifeng Tian;Lijun Sun;Ailing Wu;Zongyou Pan;Xiaolei Zhang;Jiake Xu |
| 3 | Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice | 期刊论文 | Mingbao Gu;Jie Jin;Chenghao Ren;Ximiao Chen;Weiyang Gao;Xiangyang Wang;Yaosen Wu;Naifeng Tian;Zongyou Pan;Aimin Wu;Yifei Zhou;Xiaolei Zhang |
| 4 | STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway | 期刊论文 | Qiang Guo;Ximiao Chen;Jiaoxiang Chen;Gang Zheng;Chenglong Xie;Hongqiang Wu;Zhimin Miao;Yan Lin;Jiake Xu;Weiyang Gao;Xiangtao Zheng;Zongyou Pan;Yifei Zhou;Yaosen Wu;Xiaolei Zhang |
| 5 | RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration | 期刊论文 | Zhenxuan Shao;Naifeng Tian;Xiaolei Zhang;Yifeng Shi;Zongyou Pan;Yifei Zhou;Sunlong Li;Weiyang Gao;Zhuolong Tu;Liaojun Sun;Linwei Chen;Xiangyang Wang;Yaosen Wu;Aimin Wu |
| 6 | Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2 | 期刊论文 | Jie Jin;Xinhuang Lv;Ben Wang;Chenghao Ren;Jingtao Jiang;Hongyu Chen;Ximiao Chen;Mingbao Gu;Zongyou Pan;Naifeng Tian;Ai-Min Wu;Liaojun Sun;Weiyang Gao;Jiake Xu;Xiaolei Zhang;Yaosen Wu;Yifei Zhou |
| 7 | beta-Hydroxyisovalerylshikonin inhibits IL-1β-induced chondrocyte inflammation Nrf2 and retards osteoarthritis in mice | 期刊论文 | Ximiao Chen;Mingbao Gu;Jie Jin;Chenghao Ren;Zongyou Pan;Yaosen Wu;Naifeng Tian;Aimin Wu;Liaojun Sun;Weiyang Gao;Xiangyang Wang;Chaoyong Bei;Yifei Zhou;Xiaolei Zhang |
| 8 | RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration | 期刊论文 | Zhenxuan Shao;Naifeng Tian;Zupo Yu;Xiaolei Zhang;Zongyou Pan;Yifei Zhou;Weiyang Gao;Liaojun Sun;Zaher Meftah;Linwei Chen;Xiangyang Wang;Yaosen Wu;Sunli Hu;Aimin Wu;Tianzhen Xu;Libin Ni |
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