子宫内膜异位症患者卵巢颗粒细胞EZH2通过组蛋白甲基化修饰导致女性不孕的作用机制研究
81871135
2018
H0411.女性生殖内分泌异常及相关疾病
戴永东
面上项目
助理研究员
浙江大学
57万元
组蛋白甲基化;细胞衰老;子宫内膜异位症;女性不孕;卵巢性激素合成
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Abnormal Cullin1 neddylation-mediated p21 accumulation participates in the pathogenesis of recurrent spontaneous abortion by regulating trophoblast cell proliferation and differentiation | 期刊论文 | 孙小荷;童晓嵋;郝言庆;李超;张银丽;潘熠斌;戴永东;张苔;张松英 |
| 2 | Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility | 期刊论文 | Lin Xiang;Dai Yongdong;Tong Xiaomei;Xu Wenzhi;Huang Qianmeng;Jin Xiaoying;Li Chao;Zhou Feng;Zhou Hanjin;Lin Xiaona;Huang Dong;Zhang Songying |
| 3 | NLRP3 activated macrophages promote endometrial stromal cells migration in endometriosis | 期刊论文 | Feng Zhou;Fanxuan Zhao;Qianmeng Huang;Xiang Lin;Songying Zhang;Yongdong Dai |
| 4 | 一种适用于细胞微环境的活性氧含量自动检测系统 | 专利 | 戴永东;刘璐璐;张松英;童晓嵋;林小娜;林翔;沈永行 |
| 5 | Hypoxia‑induced lactate dehydrogenaseA protects cells from apoptosis in endometriosis. | 期刊论文 | Zheng Jinyan;Dai Yongdong;Lin Xiang;Huang Qianmeng;Shi Libing;Jin Xiaoying;Liu Na;Zhou Feng;Zhang Songying |
| 6 | MiR-210-3p protects endometriotic cells from oxidative stress-induced cell cycle arrest by targeting BARD1. | 期刊论文 | Dai Yongdong;Lin Xiang;Xu Wenzhi;Lin Xiaona;Huang Qianmeng;Shi Libing;Pan Yibin;Zhang Yinli;Zhu Yunshan;Li Chao;Liu Lulu;Zhang Songying |
| 7 | 提高辅助生殖治疗效率、改善出生结局的系列技术研究和应用 | 奖励 | 张松英;林小娜;戴永东;黄东;金晓莹;刘柳;陈建敏;尉敏龄;周枫;童晓嵋;竺海燕;李超;潘熠斌 |
| 8 | Decreased expression of EZH2 in granulosa cells contributes to endometriosis-associated infertility by targeting IL-1R2 | 期刊论文 | Xiang Lin;Xiaomei Tong;Yinli Zhang;Weijia Gu;Qianmeng Huang;Yi Zhang;Feng Zhuo;Fanxuan Zhao;Xiaoying Jin;Chao Li;Dong Huang;Songying Zhang;Yongdong Dai |
| 9 | Molecular Signatures Correlated With Poor IVF Outcomes: Insights From the mRNA and lncRNA Expression of Endometriotic Granulosa Cells | 期刊论文 | Li Bing Shi;Xianjiang Wei;Bingbing Wu;Chunhui Yuan;Chao Li;Yongdong Dai;Jie Chen;Feng Zhou;Xiao-na Lin;Songying Zhang |
| 10 | 一种适用于细胞微环境的活性氧含量自动检测系统 | 专利 | 戴永东;刘璐璐;张松英;童晓嵋;林小娜;林翔;沈永行 |
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