环状RNA靶向调控内质网应激介导蛛网膜下腔出血后早期脑损伤的机制研究
81870908
2018
H0906.脑血管结构、功能异常及相关疾病
严锋
面上项目
副主任医师
浙江大学
56万元
蛛网膜下腔出血;早期脑损伤;微小RNA;内质网应激;环状RNA
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Neutrophil Extracellular Traps may be a Potential Target for Treating Early Brain Injury in Subarachnoid Hemorrhage. | 期刊论文 | Zeng Hanhai;Fu Xiongjie;Cai Jing;Sun Chenjun;Yu Mengyan;Peng Yucong;Zhuang Jianfeng;Chen Jingyin;Chen Huaijun;Yu Qian;Xu Chaoran;Zhou Hang;Cao Yang;Hu Libin;Li Jianru;Cao Shenglong;Gu Chi;Yan Feng;Chen Gao |
| 2 | Circular RNA expression profiles alter significantly after intracerebral hemorrhage in rats. | 期刊论文 | Dou Zhangqi;Yu Qian;Wang Guangyuan;Wu Shenglian;Reis Cesar;Ruan Wu;Yan Feng;Chen Gao |
| 3 | Neutrophil extracellular traps, released from neutrophil, promote microglia inflammation and contribute to poor outcome in subarachnoid hemorrhage. | 期刊论文 | Hanhai Zeng;Bin Qin;Shengjun Zhou;Jingbo Li;Yinghan Guo;Lingxin Cai;Shenglong Cao;Hang Zhou;Huaijun Chen;Jianfeng Zhuang;Yucong Peng;Xiongjie Fu;Xiaobo Yu;Xiaoxiao Tan;Jianru Li;Chi Gu;Feng Yan;Gao Chen |
| 4 | Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes. | 期刊论文 | Fu Xiongjie;Zhou Guoyang;Wu Xinyan;Xu Chaoran;Zhou Hang;Zhuang Jianfeng;Peng Yucong;Cao Yang;Zeng Hanhai;Li Yin;Li Jianru;Gao Liansheng;Chen Gao;Wang Lin;Yan Feng |
| 5 | Wogonin Accelerates Hematoma Clearance and Improves Neurological Outcome via the PPAR-γ Pathway After Intracerebral Hemorrhage. | 期刊论文 | Zhuang Jianfeng;Peng Yucong;Gu Chi;Chen Huihui;Lin Zheng;Zhou Hang;Wu Xiao;Li Jianru;Yu Xiaobo;Cao Yang;Zeng Hanhai;Fu Xiongjie;Xu Chaoran;Huang Peiyu;Cao Shenglong;Wang Chun;Yan Feng;Chen Gao |
| 6 | Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice. | 期刊论文 | Fu Xiongjie;Zeng Hanhai;Zhao Jikuang;Zhou Guoyang;Zhou Hang;Zhuang Jianfeng;Xu Chaoran;Li Jianru;Peng Yucong;Cao Yang;Li Yin;Chen Huaijun;Wang Lin;Yan Feng;Chen Gao |
| 7 | Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice | 期刊论文 | Yu Xiaobo;Zhou Guoyang;Shao Bo;Zhou Hang;Xu Chaoran;Yan Feng;Wang Lin;Chen Gao;Li Jianru;Fu Xiongjie |
| 8 | Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage. | 期刊论文 | Peng Yucong;Zhuang Jianfeng;Ying Guangyu;Zeng Hanhai;Zhou Hang;Cao Yang;Chen Huaijun;Xu Chaoran;Fu Xiongjie;Xu Hangzhe;Li Jianru;Cao Shenglong;Chen Jingyin;Gu Chi;Yan Feng;Chen Gao |
| 9 | Neutrophil to lymphocyte ratio predicting poor outcome after aneurysmal subarachnoid hemorrhage: A retrospective study and updated meta-analysis. | 期刊论文 | Yinghan Guo;Jiang Liu;Hanhai Zeng;Lingxin Cai;Tingting Wang;Xinyan Wu;Kaibo Yu;Yonghe Zheng;Huaijun Chen;Yucong Peng;Xiaobo Yu;Feng Yan;Shenglong Cao;Gao Chen |
| 10 | Intranasal wnt-3a alleviates neuronal apoptosis in early brain injury post subarachnoid hemorrhage via the regulation of wnt target PPAN mediated by the moonlighting role of aldolase C. | 期刊论文 | Ruan Wu;Hu Junwen;Zhou Hang;Li Yin;Xu Chaoran;Luo Yujie;Chen Ting;Xu Bangliang;Yan Feng;Chen Gao |
| 11 | Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH. | 期刊论文 | Zeng Hanhai;Chen Huaijun;Li Min;Zhuang Jianfeng;Peng Yucong;Zhou Hang;Xu Chaoran;Yu Qian;Fu Xiongjie;Cao Shenglong;Cai Jing;Yan Feng;Chen Gao |
| 12 | TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps via Interaction With SYK in Experimental Subarachnoid Hemorrhage | 期刊论文 | Wu Xinyan;Zeng Hanhai;Xu Chaoran;Chen Huaijun;Fan Linfeng;Zhou Hang;Yu Qian;Fu Xiongjie;Peng Yucong;Yan Feng;Yu Xiaobo;Chen Gao |
| 13 | AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury. | 期刊论文 | Zhou Hang;Hu Libin;Li Jianru;Ruan Wu;Cao Yang;Zhuang Jianfeng;Xu Hangzhe;Peng Yucong;Zhang Zhongyuan;Xu Chaoran;Yu Qian;Li Yin;Dou Zhangqi;Hu Junwen;Wu Xinyan;Yu Xiaobo;Gu Chi;Cao Shenglong;Yan Feng;Chen Gao |
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