以“病人特异性”诱导多能干细胞来源的心肌细胞为模型研究TMEM43基因突变引起致心律失常性右室心肌病的分子机制

81870175
2018
H02.循环系统
梁平
面上项目
教授
浙江大学
57万元
诱导多能干细胞;跨膜蛋白43;致心律失常性右室心肌病;心律失常;心肌细胞
2019-01-01到2022-12-31
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序号 标题 类型 作者
1 抗肿瘤药心脏毒性及机制探讨 期刊论文 杨宗块;梁平
2 Characterization of the molecular mechanisms underlying azithromycin‐induced cardiotoxicity using human‐induced pluripotent stem cell‐derived cardiomyocytes 期刊论文 Xiaochen Wang;Ziwei Pan;Jue Wang;Hongkun Wang;Hangping Fan;Tingyu Gong;Qiming Sun;Ye Feng;Ping Liang
3 表观遗传调控血管发育和稳态维持的分子机制研究及应用推广 奖励 张力;余路阳;周斌;梁平;朱建华;张晓群;陈齐山;陈婷;蒲祥元;杨峰;周逸蒋;武玉涛;王启闻
4 E2A ablation enhances proportion of nodal-like cardiomyocytes in cardiac-specific differentiation of human embryonic stem cells 期刊论文 Xiaohui Li;Fei Gao;Xiaochen Wang;Qianqian Liang;Aobing Bai;Zhuo Liu;Xinyun Chen;Ermin Li;Sifeng Chen;Chao Lu;Ruizhe Qian;Ning Sun;Ping Liang;Chen Xu
5 Generation of five induced pluripotent stem cell lines with DMD/c.497G>T mutation from renal epithelial cells of a Duchenne muscular dystrophy patient and a recessive carrier parent 期刊论文 Jun Su;Jue Wang;Long Wang;Tongyu Li;Hongkun Wang;Jiaxi Shen;Hao Wang;Jian Zhang;Weiqiang Lin;Jinyu Huang;Ping Liang
6 Establishment of an induced pluripotent stem cell line (ZJULLi004-A) from a hypertrophic cardiomyopathy patient carrying MYBPC3/c.3764C>A mutation 期刊论文 Yaxun Sun;Jingjun Zhou;Hongkun Wang;Hao Wang;Xianzhen Chen;Tingyu Gong;Ping Liang;Chenyang Jiang
7 Hyperactivation of platelet-derived growth factor signalling contributes to arrhythmogenesis in Brugada syndrome 期刊论文 Hongkun Wang;Lizhen Xu;Shuai Han;Xiaochen Wang;Hao Wang;Jingjun Zhou;Jiaxi Shen;Zongkuai Yang;Luyang Yu;Zhouqing Huang;Tingyu Gong;Ming Qi;Fan Yang;Ping Liang
8 Patient-specific iPSC-derived endothelial cells reveal aberrant p38 MAPK signaling in atypical hemolytic uremic syndrome 期刊论文 Danni Zhou;Ying Tan;Xiaoling Liu;Ling Tang;Hao Wang;Jiaxi Shen;Wei Wang;Lenan Zhuang;Juan Tao;Jun Su;Tingyu Gong;Xiaorong Liu;Ping Liang;Feng Yu;Minghui Zhao
9 一种人源性糖尿病心肌病疾病模型的建立方法 专利 梁平;唐玲;王洪坤;宫庭钰;王晓晨
10 杭州市“钱江特聘专家” 奖励 梁平
11 Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine 期刊论文 Ziwei Pan;Antje Ebert;Ping Liang
12 Generation of an induced pluripotent stem cell line from a long QT syndrome patient carrying KCNH2/1956C>A mutation 期刊论文 Fengfeng Guo;Yaxun Sun;Hongkun Wang;Hao Wang;Jingjun Zhou;Hangping Fan;Jun Su;Tingyu Gong;Chenyang Jiang;Ping Liang
13 Human induced pluripotent stem cell-derived cardiomyocytes reveal abnormal TGFβ signaling in type 2 diabetes mellitus 期刊论文 Ling Tang;Hongkun Wang;Bing Dai;Xiaochen Wang;Danni Zhou;Jiaxi Shen;Fengfeng Guo;Jue Wang;Jingjun Zhou;Hao Wang;Qingqian Wu;Hao Yao;Tingyu Gong;Jun Su;Zhuo-Xian Meng;Tianye Niu;Li Zhang;Ping Liang
14 Generation of an induced pluripotent stem cell line from a patient carrying FBN1/c.6734 G > A mutation 期刊论文 Ziwei Pan;Hongkun Wang;Hao Wang;Yong Liu;Ping Liang
15 东方心脏病学会议(OCC2020)“东方新星奖”(排名第1) 奖励 梁平
16 Generation of an induced pluripotent stem cell line from the dermal fibroblasts of a patient with arrhythmogenic right ventricular cardiomyopathy carrying a PKP2/c.2489+1G > A mutation 期刊论文 Danni Zhou;Yaxun Sun;Jiaxi Shen;Jun Su;Tingyu Gong;Chenyang Jiang;Ping Liang
17 基于人诱导多能干细胞技术的致心律失常性右室心肌病模型的研究进展 期刊论文 范航平;梁平
18 Generation of an induced pluripotent stem cell line (ZJULLi003-A) from a hypertrophic cardiomyopathy patient carrying MYH7/c.4384G>A mutation 期刊论文 Jingjun Zhou;Yaxun Sun;Hongkun Wang;Hao Wang;Fengfeng Guo;Xianzhen Chen;Tingyu Gong;Chenyang Jiang;Ping Liang
19 复杂心律失常关键技术创新及临床应用 奖励 蒋晨阳;盛夏;刘强;蒋汝红;王云鹤;叶炀;梁平;孙雅逊;程晖
20 Inhibition of HSC70 alleviates hypertrophic cardiomyopathy pathology in human induced pluripotent stem cell‐derived cardiomyocytes with a MYBPC3 mutation 期刊论文 Hangyuan Qiu;Yaxun Sun;Ziwei Pan;Jingjun Zhou;Hongkun Wang;Xiaochen Wang;Dongsheng Cai;Guosheng Fu;Tingyu Gong;Chenyang Jiang;Ping Liang
21 瞬时受体电位M4 通道与心血管疾病的研究进展 期刊论文 范航平;王洪坤;王晓晨;梁平
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