nesfatin-1调控RhoA/ROCK信号通路在骨关节炎软骨细胞骨架重塑过程中的作用及机制研究

81801371
2018
H1902.衰老相关疾病
蒋利锋
青年科学基金项目
副主任医师
浙江大学
21万元
骨关节炎;RhoA/ROCK通路;细胞骨架;nesfatin-1
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Ochronotic arthritis and ochronotic Achilles tendon rupture in alkaptonuria A 6 years follow-up case report in China 期刊论文 Jiang Lifeng;Cao Le;Fang Jinghua;Yu Xinning;Dai Xuesong;Miao Xudong
2 Nesfatin-1 suppresses interleukin-1 beta-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats 期刊论文 Jiang Lifeng;Xu Kai;Li Jin;Zhou Xindie;Xu Langhai;Wu Zhipeng;Ma Chiyuan;Ran Jisheng;Hu Pengfei;Bao Jiapeng;Wu Lidong;Xiong Yan
3 The elevated expression of IL-38 serves as an anti-inflammatory factor in osteoarthritis and its protective effect in osteoarthritic chondrocytes 期刊论文 Lifeng Jiang;Xindie Zhou;Congxiang Huang;Jiapeng Bao;Jin Li;Kai Xu;Dahai Dong;Lidong Wu
4 Down-regulated ciRS-7/up-regulated miR-7 axis aggravated Cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis 期刊论文 Zhou Xindie;Li Jin;Zhou Yuanshuai;Yang Zhicheng;Yang Haoyu;Li Dong;Zhang Junjie;Zhang Yi;Xu Nanwei;Huang Yong;Jiang Lifeng
5 Association between interleukin-17A/F single nucleotide polymorphisms and susceptibility to osteoarthritis in a Chinese population 期刊论文 Jiang Lifeng;Zhou Xindie;Xiong Yan;Bao Jiapeng;Xu Kai;Wu Lidong
6 Nesfatin-1 Promotes the Osteogenic Differentiation of Tendon-Derived Stem Cells and the Pathogenesis of Heterotopic Ossification in Rat Tendons via the mTOR Pathway 期刊论文 Xu Kai;Zhang Zhanfeng;Chen Mengyao;Moqbel Safwat Adel Abdo;He Yuzhe;Ma Chiyuan;Jiang Lifeng;Xiong Yan;Wu Lidong
7 miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway 期刊论文 Lifeng Jiang;Xindie Zhou;Kai Xu;Pengfei Hu;Jiapeng Bao;Jin Li;Junfeng Zhu;Lidong Wu
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