REJ-C1G3诱导Brd4降解的机制及其抗肿瘤活性研究

81672955
2016
H1814.肿瘤化学药物治疗
薛玉花
面上项目
副教授
厦门大学
59万元
多聚泛素化;3;抗肿瘤;原花青素C-1;3′;溴结构域蛋白4;3″-三-O-棓酸酯
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 ELL-associated factors EAF1/2 negatively regulate HIV-1 transcription through inhibition of Super Elongation Complex formation 期刊论文 Rongdiao Liu;Chunjing Chen;Yun Li;Qingqing Huang;Yuhua Xue
2 Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors 期刊论文 Hongyu Hu;Jun Wu;Mingtao Ao;Xiaoping Zhou;Boqun Li;Zhenzhen Cui;Tong Wu;Lijuan Wang;Yuhua Xue;Zhen Wu;Meijuan Fang
3 Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2 期刊论文 Jun Wu;Yuhua Xue;Xiang Gao;Qiang Zhou
4 Synthesis and biological evaluations of N '-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents 期刊论文 Li Baicun;Zhu Feifeng;He Fengming;Huang Qingqing;Liu Xiaoguang;Wu Tong;Zhao Taige;Qiu Yingkun;Wu Zhen;Xue Yuhua;Fang Meijuan
5 The role of autophagy in the pathogenesis of exposure keratitis 期刊论文 Wang Guoliang;Xue Yuhua;Wang Yanzi;Dong Fei;Shen Mei;Zong Rongrong;Liu Zuguo;Li Cheng
6 A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter 期刊论文 Wu Jun;Ao Ming tao;Shao Rui;Wang Hui Ru;Yu Diao;Fang Mei Juan;Gao Xiang;Wu Zhen;Zhou Qiang;Xue Yu hua
7 A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis 期刊论文 Yu Dan;Cattoglio Claudia;Xue Yuhua;Zhou Qiang
8 Protective Effects Oncorneal Endothelium During Intracameral Irrigation Using N-(2)-l-alanyl-l-Glutamine 期刊论文 Mengyi Jin;Yanzi Wang;Yixin Wang;Yunpeng Li;Guoliang Wang;Xuezhi Liu;Yuhua Xue;Zuguo Liu;Cheng Li
9 Onion Epithelial Membrane Scaffolds Transfer Corneal Epithelial Layers in Reconstruction Surgery 期刊论文 Wang Guoliang;Chen Pei;Wang Yanzi;Wang Yixin;Reinach Peter S.;Xue Yuhua;Liu Zuguo;Li Cheng
10 Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription 期刊论文 Tang Dan;Chen Chunjing;Liao Ga;Liu Jiaming;Liao Banghua;Huang QingQing;Chen Qianqian;Zhao Jiahui;Jiang Hui;Duan Jinsong;Huang Jin;Wang Kunjie;Wang Jiawei;Zhou Cuiyan;Chu Wendan;Li Wenqi;Sun Bo;Li Zhonghan;Dai Lunzhi;Fu Xianghui;Cheng Wei;Xue Yuhua;Qi Shiqian
11 Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1 期刊论文 Ao Mingtao;Pan Zhenrui;Qian Yuqing;Tang Bowen;Feng Zeming;Fang Hua;Wu Zhen;Chen Jingwei;Xue Yuhua;Fang Meijuan
12 多酚提取物及其组合物在制备HIV潜伏病毒库激活剂的应用 专利 薛玉花;潘振瑞;黄晴晴
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