新型抗体对慢性乙型肝炎病毒感染的治疗作用与机制研究
81672023
2016
H2103.肝炎病毒与感染
袁权
面上项目
教授
厦门大学
57万元
治疗性抗体;乙型肝炎病毒;持续性病毒感染;抗病毒治疗;免疫治疗
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A cell-penetrating whole molecule antibody targeting intracellular HBx suppresses hepatitis B virus via TRIM21-dependent pathway | 期刊论文 | Zhang Jun-Fang;Xiong Hua-Long;Cao Jia-Li;Wang Shao-Juan;Guo Xue-Ran;Lin Bi-Yun;Zhang Ying;Zhao Jing-Hua;Wang Ying-Bin;Zhang Tian-Ying;Yuan Quan;Zhang Jun;Xia Ning-Shao |
| 2 | Polypeptides and antibodies for treating hbv infection and related diseases_EP | 专利 | Yuan Quan;Zhang Tianying;Luo Wenxin;Chen Yixin;Zhang Jun;Xia Ningshao |
| 3 | A novel toolbox for the in vitro assay of hepatitis D virus infection | 期刊论文 | Zhao Jing Hua;Zhang Ya Li;Zhang Tian Ying;Yuan Lun Zhi;Cheng Tong;Chen Pei Jer;Yuan Quan;Xia Ning Shao |
| 4 | Polypeptides and antibodies for treating HBV infection and related diseases | 专利 | Yuan Quan;Zhang Tianying;Luo Wenxin;Chen Yixin;Zhang Jun;Xia Ningshao |
| 5 | A unique B cell epitope-based particulate vaccine shows effective suppression of hepatitis B surface antigen in mice | 期刊论文 | Zhang Tian-Ying;Guo Xue-Ran;Wu Yang-Tao;Kang Xiao-Zhen;Zheng Qing-Bing;Qi Ruo-Yao;Chen Bin-Bing;Lan Ying;Wei Min;Wang Shao-Juan;Xiong Hua-Long;Cao Jia-Li;Zhang Bao-Hui;Qiao Xiao-Yang;Huang Xiao-Fen;Wang Ying-Bin;Fang Mu-Jin;Ya-Li Zhang;Cheng Tong;Chen Yi-Xin;Zhao Qin-Jian;Li Shao-Wei;Ge Sheng-Xiang;Chen Pei-Jer;Zhang Jun;Yuan Quan;Xia Ning-Shao |
| 6 | Polypeptides and antibodies for treating hbv infection and related diseases_CA | 专利 | Yuan Quan;Zhang Tianying;Luo Wenxin;Chen Yixin;Zhang Jun;Xia Ningshao |
| 7 | Agonist c-Met Monoclonal Antibody Augments the Proliferation of hiPSC-derived Hepatocyte-Like Cells and Improves Cell Transplantation Therapy for Liver Failure in Mice | 期刊论文 | Yuan Lunzhi;Zhang Yali;Liu Xuan;Chen Yao;Zhang Liang;Cao Jiali;Li Xiaoling;Wang Mingfeng;Wu Kun;Zhang Jun;Liu Gang;Tang Qiyi;Yuan Quan;Cheng Tong;Xia Ningshao |
| 8 | The unique antibody suppresses HBV viremia and reduces hepatocarcinogenesis in HBV-transgenic mice | 期刊论文 | Kang Xiao-Zhen;Guo Xue-Ran;Chen Bin-Bing;Zhang Tian-Ying;Yuan Quan;Chen Pei-Jer;Chen Pei-Jer;Xia Ning-Shao |
| 9 | HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation | 期刊论文 | Yuan Lunzhi;Jiang Jing;Liu Xuan;Zhang Yali;Zhang Liang;Xin Jiaojiao;Wu Kun;Li Xiaoling;Cao Jiali;Guo Xueran;Shi Dongyan;Li Jun;Jiang Longyan;Sun Suwan;Wang Tengyun;Hou Wangheng;Zhang Tianying;Zhu Hua;Zhang Jun;Yuan Quan;Cheng Tong;Li Jun;Xia Ningshao |
| 10 | 用于治疗HBV感染及相关疾病的多肽及抗体 | 专利 | 袁权;张天英;罗文新;陈毅歆;张军;夏宁邵 |
| 11 | Polypeptides and antibodies for treating HBV infection and related diseases_AU | 专利 | Yuan Quan;Zhang Tianying;Luo Wenxin;Chen Yixin;Zhang Jun;Xia Ningshao |
| 12 | Nanobody-based sandwich reporter system for living cell sensing influenza A virus infection | 期刊论文 | Cao Jiali;Zhong Nicole;Wang Guosong;Wang Mingfeng;Zhang Baohui;Fu Baorong;Wang Yingbin;Zhang Tianying;Zhang Yali;Yang Kunyu;Chen Yixin;Yuan Quan;Xia Ningshao |
| 13 | Robust in vitro assay for analyzing the neutralization activity of serum specimens against hepatitis B virus | 期刊论文 | Zhang Ya Li;Gao Ying;Cao Jia Li;Zhao Jing Hua;Zhang Tian Ying;Yang Chuan Lai;Xiong Hua Long;Wang Ying Bin;Ou Shan Hai;Cheng Tong;Chen Chang Rong;Yuan Quan;Xia Ning Shao |
| 14 | Polypeptides and antibodies for treating HBV infection and related diseases | 专利 | Yuan Quan;Zhang Tianying;Luo Wenxin;Chen Yixin;Zhang Jun;Xia Ningshao |
| 15 | Antibody-mediated immunotherapy against chronic hepatitis B virus infection | 期刊论文 | Gao Ying;Zhang Tian Ying;Yuan Quan;Xia Ning Shao |
| 16 | Bioinspired Artificial Nanodecoys for Hepatitis B Virus | 期刊论文 | Liu Xuan;Yuan Lunzhi;Zhang Liang;Mu Yalin;Li Xiaoling;Liu Chao;Lv Peng;Zhang Yali;Cheng Tong;Yuan Quan;Xia Ningshao;Chen Xiaoyuan;Liu Gang |
| 17 | Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction | 期刊论文 | Zhang Tian Ying;Chen Hong Ying;Cao Jia Li;Xiong Hua Long;Mo Xiao Bing;Li Tian Liang;Kang Xiao Zhen;Zhao Jing Hua;Yin Bo;Zhao Xiang;Huang Cheng Hao;Yuan Quan;Xue Ding;Xia Ning Shao;Yuan Y Adam |
| 18 | Detection of HBV Covalently Closed Circular DNA | 期刊论文 | Li Xiaoling;Zhao Jinghua;Yuan Quan;Xia Ningshao |
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