亲神经亚型梅毒螺旋体通过mTOR信号通路诱导Th细胞分化并促进免疫逃逸的作用及其机制
81471231
2014
H0909.神经系统炎症、感染及相关疾病
刘莉莉
面上项目
教授
厦门大学
70万元
神经梅毒;辅助性T淋巴细胞;mTOR信号通路;小胶质细胞;梅毒螺旋体
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | LncRNA Expression in CD4+ T Cells in Neurosyphilis Patients. | 期刊论文 | Liu Li-Li;Zhu Shao-Gang;Jiang Xiao-Yong;Ren Jun;Lin Yong;Zhang Ning-Ning;Tong Man-Li;Zhang Hui-Lin;Zheng Wei-Hong;Fu Hua-Jun;Luo Hai-Juan;Lin Li-Rong;Yan Jiang-Hua;Yang Tian-Ci |
| 2 | 梅毒螺旋体IgM 抗体生物素亲和素酶联免疫检测试剂盒及其制备方法 | 专利 | 童曼莉;林丽蓉;刘莉莉;张惠林;杨天赐;张长弓 |
| 3 | 梅毒的临床与诊断系列研究 | 奖励 | 林丽蓉;童曼莉;牛建军;刘莉莉;郑维红;张惠林;杨天赐 |
| 4 | Clinical and laboratory characteristics in patients suffering from general paresis in the modern era | 期刊论文 | Chen Yu-Yan;Zhang Ya-Feng;Qiu Xin-Hui;Zhang Qiao;Chen Fu-Yi;Liu Long;Fan Jin-Yi;Gao Kun;Zhu Xiao-Zhen;Zheng Wei-Hong;Zhang Hui-Lin;Lin Li-Rong;Liu Li-Li;Tong Man-Li;Niu JJ;Yang Tian-Ci |
| 5 | Re-evaluating the sensitivity of the rabbit infectivity test for Treponema pallidum in modern era | 期刊论文 | Tong Man-Li;Zhang Hui-Lin;Zhu Xiao-Zhen;Fan Jin-Yi;Gao Kun;Lin Li-Rong;Liu Li-Li;Li Shu-Lian;Lin Hui-Ling;Lin Zhi-Feng;Niu Jian-Jun;Zheng Wei-Hong;Yang TC |
| 6 | 梅毒螺旋体总抗体生物素亲和素酶联免疫检测试剂盒的其制备方法 | 专利 | 林丽蓉;童曼莉;刘莉莉;张惠林;杨天赐;张长弓 |
| 7 | Serological Response Predicts Normalization of Cerebrospinal Fluid Abnormalities at Six Months after Treatment in HIV-Negative Neurosyphilis Patients | 期刊论文 | Xiao Yao;Tong Man-Li;Lin Li-Rong;Liu Li-Li;Gao Kun;Chen Mei-Jun;Zhang Hui-Lin;Zheng Wei-Hong;Li Shu-Lian;Lin Hui-Ling;Lin Zhi-Feng;Yang TC;Niu JJ |
| 8 | Factors associated with syphilis infection: a comprehensive analysis based on a case-control study | 期刊论文 | Xiao Y.;Li S. -L.;Lin H. -L.;Lin Z. -F.;Zhu X. -Z.;Fan J. -Y.;Gao K.;Zhang H. -L.;Lin L. -R.;Liu L. -L.;Tong M. -L.;Niu J. -J.;Yang T. -C. |
| 9 | The evaluation method for assessing a diagnostic test of HIV: Some noteworthy issues | 期刊论文 | Niu Jian-Jun;Zhang Qiao;Chen Fu-Yi;Liu Long;Liu Li-Li;Yang Tian-Ci |
| 10 | CXCL13 chemokine as a promising biomarker to diagnose neurosyphilis in HIV-negative patients | 期刊论文 | Zeng Yan-Li;Lin Yi-Qiang;Zhang Ning-Ning;Zou Chao-Ning;Zhang Hui-Lin;Peng Feng;Liu Zhao-Ji;Zheng Wei-Hong;Yan Jiang-Hua;Liu Li-Li |
| 11 | Novel predictors of neurosyphilis among HIV-negative syphilis patients with neurological symptoms: an observational study (vol 17, 310, 2017) | 期刊论文 | Xiao Yao;Tong Man-Li;Liu Li-Li;Lin Li-Rong;Chen Mei-Jun;Zhang Hui-Lin;Zheng Wei-Hong;Li Shu-Lian;Lin Hui-Ling;Lin Zhi-Feng;Xing Hui-Qin;Niu Jian-Jun;Yang Tian-Ci |
| 12 | 梅毒系列实验检测技术的创建与临床研究 | 奖励 | 杨天赐;林丽蓉;刘莉莉;牛建军;童曼莉;张惠林;郑维红 |
| 13 | 梅毒系列检测技术的建立及其临床应用 | 奖励 | 杨天赐;童曼莉;牛建军;刘莉莉;林丽蓉;张惠林;郑维红 |
| 14 | 梅毒螺旋体IgG 抗体生物素亲和素酶联免疫检测试剂盒及其制备方法 | 专利 | 张惠林;林丽蓉;童曼莉;刘莉莉;杨天赐;张长弓 |
| 15 | Whole genome sequence of the Treponema pallidum subsp pallidum strain Amoy: An Asian isolate highly similar to SS14 | 期刊论文 | Tong Man-Li;Zhao Qiang;Liu Li-Li;Zhu Xiao-Zhen;Gao Kun;Zhang Hui-Lin;Lin Li-Rong;Niu Jian-Jun;Ji Zhi-Liang;Yang Tian-Ci |
| 16 | Evaluation of the Boson Chemiluminescence Immunoassay as a First-Line Screening Test in the ECDC Algorithm for Syphilis Serodiagnosis in a Population with a High Prevalence of Syphilis | 期刊论文 | Qiu Xin-Hui;Zhang Ya-Feng;Chen Yu-Yan;Zhang Qiao;Chen Fu-Yi;Fan Jin-Yi;Gao Kun;Zhu Xiao-Zhen;Zheng Wei-Hong;Zhang Hui-Lin;Lin Li-Rong;Liu Li-Li;Tong Man-Li;Zhang Chang-Gong;Niu Jian-Jun;Yang Tian-Ci |
| 17 | A negative nontreponemal and/or specific antitreponemal IgM test does not exclude active infectious syphilis: evidence from a rabbit infectivity test A case report | 期刊论文 | Lin Li-Rong;Tong Man-Li;Gao Kun;Zhu Xiao-Zhen;Fan Jin-Yi;Zheng Wei-Hong;Li Shu-Lian;Lin Hui-Ling;Liu Li-Li;Yang Tian-Ci |
| 18 | 梅毒的实验诊断与临床研究 | 奖励 | 刘莉莉;牛建军;林丽蓉;杨天赐;童曼莉;张惠林;郑维红 |
| 19 | 梅毒螺旋体特异性抗体定量检测试剂盒及其制备方法 | 专利 | 林丽蓉;杨天赐;刘莉莉;张惠林;童曼莉;张长弓 |
| 20 | Development of tissue inflammation accompanied by NLRP3 inflammasome activation in rabbits infected with Treponema pallidum strain Nichols | 期刊论文 | Lin Li-Rong;Xiao Yao;Liu Wei;Zhu Xiao-Zhen;Gao Zheng-Xiang;Gao Kun;Tong Man-Li;Zhang Hui-Lin;Li Shu-Lian;Lin Hui-Ling;Li Wen-Dong;Liang Xian-Ming;Lin Y;Liu LL;Yang TC |
| 21 | 梅毒螺旋体特异性抗体高通量检测试剂盒及其制备方法 | 专利 | 杨天赐;刘莉莉;张惠林;童曼莉;林丽蓉;张长弓 |
| 22 | Akt, mTOR and NF-kappa B pathway activation in Treponema pallidum stimulates M1 macrophages | 期刊论文 | Lin Li-Rong;Gao Zheng-Xiang;Lin Yong;Zhu Xiao-Zhen;Liu Wei;Liu Dan;Gao Kun;Tong Man-Li;Zhang Hui-Lin;Liu Li-Li;Xiao Yao;Niu Jian-Jun;Yang Tian-Ci |
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