TLR4信号通路在微量尼古丁刺激增强树突状细胞抗原交叉提呈中的作用研究

81273203
2012
H1102.免疫应答异常
高丰光
面上项目
教授
厦门大学
70万元
肿瘤;树突状细胞;交叉提呈;尼古丁;免疫治疗
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Nicotine exerts neuroprotective effects against beta-amyloid-induced neurotoxicity in SH-SY5Y cells through the Erk1/2-p38-JNK-dependent signaling pathway 期刊论文 Xue Mao Qiang|Liu Xiao Xing|Zhang Yan Ling|Gao Feng Guang|
2 Upregulation of ABCG2 via the PI3K-Akt pathway contributesto acidic microenvironment-induced cisplatin resistancein A549 and LTEP-a-2 lung cancer cells 期刊论文 Hu Chun Fang|Huang Yi Ying|Wang Yong Jie|Gao Feng Guang|
3 Increased translocation of antigens to endosomes and TLR4mediated endosomal recruitment of TAP contribute to nicotineaugmented cross-presentation 期刊论文 Hu Chun Fang|Li Juan|You Xiang|Gao Feng Guang|
4 Camptothecin and cisplatin upregulate ABCG2 and MRP2 expression by activating the ATM/NF-κB pathway in lung cancer cells. 期刊论文 Zhang Yue Hua|Wang Yi Nan|Wu Bin|Gao Feng Guang|
5 Ataxia-telangiectasia mutated activation mediates tumornecrosis factor-alpha induced MMP-13 up-regulation andmetastasis in lung cancer cells 期刊论文 You Xiang|Shi Lei|Li Qing|Gao Feng Guang|
6 TIPE2 inhibits TNF-α-induced hepatocellular carcinoma cell metastasis via Erk1/2 downregulation and NF-κB activation. 期刊论文 Wang Yan Yan|Jiang Yi Na|Wang Yi Nan|Gao Feng Guang|
7 Increased antigen presentation but impaired T cells priming after upregulation of interferon-beta induced by lipopolysaccharides is mediated by upregulation of B7H1 and GITRL. 期刊论文 You Xiang|Qiu Xin Hui|Wang Yi Nan|Gao Feng Guang|
8 Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation. 期刊论文 Zhang Yue Hua|Wang Yi Nan|Li Juan|Gao Feng Guang|
9 Ex vivo nicotine stimulation augments the efficacy of human peripheral blood mononuclear cell-derived dendritic cell vaccination via activating Akt-S6 pathway. 期刊论文 Gu Jiao Jiao|Wang Yi Nan|Li Qing|Gao Feng Guang|
10 Interleukin 6 trigged ataxia-telangiectasia mutatedactivation facilitates lung cancer metastasis via MMP-3/MMP-13 up-regulation 期刊论文 Xiaobo Huang|Yinan Wang|Qing Li|Fengguang Gao|
11 Nicotine promotes cell proliferation and induces resistance to cisplatin by a7 nicotinic acetylcholine receptor-mediated activation in Raw264.7 and El4 cells 期刊论文 Bai Zhen Huan|Chen Qiong Yun|Zhang Ye|Gao Feng Guang|
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