鸡白痢沙门菌致病岛-2 T3SS效应蛋白致病与免疫的分子机制

31230070
2012
C1804.兽医免疫学
焦新安
重点项目
教授
扬州大学
285万元
致病;II型毒力岛;鸡白痢沙门菌;免疫;效应蛋白
2013-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Virulence determinants of Salmonella Gallinarum biovar Pullorum identified by PCR signature-tagged mutagenesis and the spiC mutant as a candidate live attenuated vaccine 期刊论文 Geng Shizhong;Jiao Xinan;Barrow Paul;Pan Zhiming;Chen Xiang
2 猪霍乱沙门菌疫苗株C500毒力致弱的主要原因是rpoS基因的缺失(英文) 期刊论文 徐黎娟;李求春;刘杰;胡亚辰;陶明新;谢晓蕾;耿士忠;焦新安
3 Characterization of CRISPR-Cas system in clinical Staphylococcus epidermidis strains revealed its potential association with bacterial infection sites 期刊论文 Li Qiuchun;Xie Xiaolei;Yin Kequan;Tang Yueyuan;Zhou Xiaohui;Chen Yun;Xia Jie;Hu Yachen;Ingmer Hanne;Li Yang;Jiao Xinan
4 鸡白痢沙门菌S06004株致病岛-2缺失株的构建及其生物学特性 期刊论文 殷俊磊;吴颖斐;蔺志杰;王晓春;胡亚辰;李求春;耿士忠;焦新安
5 Genetic analysis of Salmonella enterica serovar Gallinarum biovar Pullorum based on characterization and evolution of CRISPR sequence 期刊论文 Xie Xiaolei;Hu Yachen;Xu Yaohui;Yin Kequan;Li Yang;Chen Yun;Xia Jie;Xu Lijuan;Liu Zijian;Geng Shizhong;Li Qiuchun;Jiao Xinan;Chen Xiang;Pan Zhiming
6 沙门菌致病岛2Ⅲ型分泌系统研究进展 期刊论文 殷俊磊;李求春;焦新安
7 鸡白痢沙门菌spiC-rfaH双基因敲除减毒株及其DIVA疫苗应用 专利 焦新安;郭荣显;耿士忠;焦扬;朱姗姗;潘志明;孙林;陈祥;李求春
8 模式识别受体介导的病原免疫逃逸 期刊论文 胡茂志;潘志明;焦新安
9 鸡白痢沙门菌spiC-rfaL双基因敲除减毒株及其DIVA疫苗应用 专利 焦新安;郭荣显;耿士忠;焦扬;朱姗姗;潘志明;孙林;陈祥;李求春
10 鸡白痢沙门菌spiC-rfaJ双基因敲除减毒株及其DIVA疫苗应用 专利 焦新安;郭荣显;耿士忠;焦扬;朱姗姗;潘志明;孙林;陈祥;李求春
11 鸡白痢沙门菌spiC基因克隆与生物信息学分析 期刊论文 安树敏;郭荣显;薛颖;潘志明;耿士忠;焦新安
12 鸡白痢沙门菌sifA基因缺失株的构建及其生物学特性的研究 期刊论文 殷俊磊;徐黎娟;王志鹏;蔺志杰;李求春;耿士忠;焦新安
13 High-Efficiency, Two-Step Scarless-Markerless Genome Genetic Modification in Salmonella enterica 期刊论文 Geng Shizhong;Tian Qin;An Shuming;Pan Zhiming;Chen Xiang;Jiao Xinan
14 鸡白痢沙门菌SpiC蛋白的原核表达及其应用 期刊论文 耿士忠;刘欢;焦新安;潘志明;钱珊珊;郭荣显;安树敏;薛颖
15 雏沙门菌S06004株毒力岛1缺失株的构建及其基本生物学特性的测定 期刊论文 殷俊磊;程瞾;夏静;谢晓蕾;陶明新;李求春;耿士忠;焦新安
16 Complete Genome Sequence of Salmonella enterica Serovar Pullorum Multidrug Resistance Strain S06004 from China 期刊论文 Li Qiuchun;Hu Yachen;Wu Yinfei;Wang Xiaochun;Xie Xiaolei;Tao Mingxin;Yin Junlei;Lin Zhijie;Jiao Yang;Xu Lijuan;Jiao Xinan
17 一种快速鉴定特定血清型沙门菌的PCR检测试剂盒 专利 焦新安;潘志明;熊丹;宋丽;焦扬;孙林;陈祥;耿士忠;黄金林;殷月兰
18 Salmonella isolated from the slaughterhouses and correlation with pork contamination in free market 期刊论文 Li Yuchen;Cai Yinqiang;Tao Jing;Kang Xilong;Jiao Yang;Guo Rongxian;Wang Guoliang;Pan Zhiming;Jiao Xinan
19 沙门菌CRISPR的结构与功能研究进展 期刊论文 蔡银强;李求春;陶静;蒋道军;潘志明;焦新安
20 Immunogenicity and protective efficacy of Salmonella enterica serovar Pullorum pathogenicity island 2 mutant as a live attenuated vaccine candidate 期刊论文 Yin Junlei;Cheng Zhao;Xu Lijuan;Li Qiuchun;Geng Shizhong;Pan Zhiming;Jiao Xinan
21 鸡白痢沙门菌spiC::km突变株减毒效应的病理学观察 期刊论文 耿士忠;安树敏;曾玲;郭荣显;薛颖;蒋远远;潘志明;焦新安
22 重要食源性人兽共患病原菌的传播生态规律及其防控技术 奖励 焦新安;方维焕;黄金林;李肖梁;潘志明;陈健舜;杨振泉;江玲丽;巢国祥;陈祥;殷月兰;耿士忠;姚德法;郑国军;李郁;刘佩红;李文良;陈昌海;李求春;孙林;俞盈;李丽萍;叶斌
23 一种用于蓝白斑筛选的自杀载体pGMB152及其应用 专利 焦新安;耿士忠;田青;潘志明;陈祥;孙林;胡茂志
24 沙门菌病 专著 焦新安
25 鸡白痢沙门菌中三型分泌系统-2效应蛋白基因分布研究 期刊论文 殷俊磊;程瞾;夏静;李求春;耿士忠;焦新安
26 沙门菌毒力岛的研究进展 期刊论文 薛颖;郭荣显;钱珊珊;安树敏;焦新安;耿士忠
27 Identification by PCR signature-tagged mutagenesis of attenuated Salmonella Pullorum mutants and corresponding genes in a chicken embryo model 期刊论文 Geng Shizhong;Tian Qin;Guo Rongxian;Jiao Yang;Barrow Paul;Yin Chao;Wang Yaonan;Geng Haopeng;Pan Zhiming;Jiao Xinan
28 Influence of Salmonella enterica serovar Pullorum pathogenicity island 2 on type III secretion system effector gene expression in chicken macrophage HD11 cells 期刊论文 Yin Junlei;Chen Yun;Xie Xiaolei;Xia Jie;Li Qiuchun;Geng Shizhong;Jiao Xinan
29 O-polysaccharide is important for Salmonella Pullorum survival in egg albumen, and virulence and colonization in chicken embryos 期刊论文 Guo Rongxian;Li Zhuoyang;Jiao Yang;Geng Shizhong;Pan Zhiming;Chen Xiang;Li Qiuchun;Jiao Xinan
30 Evaluation of the Salmonella enterica Serovar Pullorum Pathogenicity Island 2 Mutant as a Candidate Live Attenuated Oral Vaccine 期刊论文 Yin Junlei;Cheng Zhao;Wang Xiaochun;Xu Lijuan;Li Qiuchun;Geng Shizhong;Jiao Xinan
31 鸡白痢沙门菌分泌性蛋白SpiC的用途 专利 焦新安;耿士忠;潘志明;刘欢;孙林
32 鸡白痢沙门菌spiC-rfc双基因敲除减毒株及其DIVA疫苗应用 专利 焦新安;郭荣显;耿士忠;焦扬;朱姗姗;潘志明;孙林;陈祥;李求春
33 沙门菌怀特-考夫曼-勒密诺抗原表中Kauffmann正确拼写的考证 期刊论文 耿士忠;耿浩鹏;王耀楠;李求春;黄金林;潘志明;焦新安
34 鸡白痢沙门菌S06004ΔspiC突变株的构建与鉴定 期刊论文 耿士忠;刘男男;焦新安;刘欢;郭荣显;钱珊珊;李昱辰;潘志明
35 Construction and characterization of a cigR deletion mutant of Salmonella enterica serovar Pullorum 期刊论文 Yin Junlei;Xia Jie;Tao Mingxin;Xu Lijuan;Li Qiuchun;Geng Shizhong;Jiao Xinan
36 Safety, Protective Immunity, and DIVA Capability of a Rough Mutant Salmonella Pullorum Vaccine Candidate in Broilers 期刊论文 Guo Rongxian;Jiao Yang;Li Zhuoyang;Zhu Shanshan;Fei Xiao;Geng Shizhong;Pan Zhiming;Chen Xiang;Li Qiuchun;Jiao Xinan
37 鸡白痢沙门菌spiC-rfaI双基因敲除减毒株及其DIVA疫苗应用 专利 焦新安;郭荣显;耿士忠;焦扬;朱姗姗;潘志明;孙林;陈祥;李求春
38 Safety and protective efficacy of a spiC and crp deletion mutant of Salmonella gallinarum as a live attenuated vaccine for fowl typhoid 期刊论文 Cheng Zhao;Yin Junlei;Kang Xilong;Geng Shizhong;Hu Maozhi;Pan Zhiming;Jiao Xinan
39 Prevalence, Characteristics, and Antimicrobial Resistance Patterns of Salmonella in Retail Pork in Jiangsu Province, Eastern China 期刊论文 Li Yu-Chen;Pan Zhi-Ming;Kang Xi-Long;Geng Shi-Zhong;Liu Zhong-Yi;Cai Yin-Qiang;Jiao Xin-An
40 鸡白痢沙门菌研究进展 期刊论文 殷俊磊;李求春;耿士忠;潘志明;焦新安
41 Identification of Salmonella enterica Serovar Pullorum Antigenic Determinants Expressed In Vivo 期刊论文 Li Qiuchun;Hu Yachen;Chen Jing;Liu Zhicheng;Han Jun;Sun Lin;Jiao Xinan
42 Responses of macrophages against Salmonella infection compared with phagocytosis 期刊论文 Hu Maozhi;Yang Yun;Meng Chuang;Pan Zhiming;Jiao Xinan
43 Phenotypic characteristics and genotypic correlation between Salmonella isolates from a slaughterhouse and retail markets in Yangzhou, China 期刊论文 Cai Yinqiang;Tao Jing;Jiao Yang;Fei Xiao;Zhou Le;Wang Yan;Zheng Huijuan;Pan Zhiming;Jiao Xinan
44 肠炎沙门菌lpfC基因缺失株的构建及基本生物学特性研究 期刊论文 王晓春;焦扬;程瞾;吴颖斐;康喜龙;胡亚辰;李求春;焦新安
45 Evaluation of protective efficacy of a novel inactivated Salmonella Pullorum ghost vaccine against virulent challenge in chickens 期刊论文 Guo Rongxian;Geng Shizhong;Jiao Hongmei;Pan Zhiming;Chen Xiang;Jiao Xinan
46 利用SCOTS技术筛选鸡白痢沙门菌感染巨噬细胞的转录序列 期刊论文 李求春;方丽君;陈静;谢晓蕾;陶明新;王晓春;吴颖斐;焦新安
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