基于细胞膜纳米囊泡的肝癌疫苗递送系统的设计、构建及性能研究
U1705281
2017
B0404.化学与生物传感
刘刚
联合基金项目
教授
厦门大学
204万元
分子影像;肝癌;药物载体;免疫治疗;纳米生物技术
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Mimovirus Vesicle-based Biological Orthogonal Reaction for Cancer Diagnosis | 期刊论文 | En Ren;Chengchao Chu;Yunming Zhang;Junqing Wang;Xin Pang;Xiaoning Lin;Chao Liu;Xiaoxiao Shi;Qixuan Dai;Peng Lv;Xiaomin Wang;Xiaoyuan Chen;Gang Liu |
| 2 | Genetically engineered liposome-like nanovesicles as active targeted transport platform | 期刊论文 | Pengfei Zhang;Long Zhang;Zainen Qin;Suhang Hua;Zhide Guo;Chengchao Chu;Huirong Lin;Yang Zhang;Wengang Li;Xianzhong Zhang;Xiaoyuan Chen;Gang Liu |
| 3 | Metal-organic Nanostructure Based on TixOy/Ruthenium Reaction Units: For CT/MR Imaging-Guided X-ray Induced Dynamic Therapy | 期刊论文 | Dongsheng Li;Qixuan Dai;Hu Chen;Huirong Lin;Zhixiang Lu;Huili Zheng;Peng Lv;Wei Li;Gang Liu;Chengchao Chu |
| 4 | Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy | 期刊论文 | Peng Lv;Xuan Liu;Xiaomei Chen;Chao Liu;Yang Zhang;Chengchao Chu;Junqing Wang;Xiaoyong Wang;Xiaoyuan Chen;Gang Liu |
| 5 | Polysaccharide-based Controlled Release Systems for Therapeutics Delivery and Tissue Engineering: from Bench to Bedside | 期刊论文 | Tianxin Miao;Junqing Wang;Yun Zeng;Gang Liu;Xiaoyuan Chen |
| 6 | Advancing the Pharmaceutical Potential of Bio-inorganic Hybrid Lipid-based Assemblies | 期刊论文 | Junqing Wang;Angela Zhe Wang;Peng Lv;Wei Tao;Gang Liu |
| 7 | Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics | 期刊论文 | Yang Zhang;Xiaoyong Wang;Chengchao Chu;Zijian Zhou;Biaoqi Chen;Xin Pang;Gan Lin;Huirong Lin;Yuxin Guo;En Ren;Peng Lv;Yesi Shi;Qingbing Zheng;Xiaohui Yan;Xiaoyuan Chen;Gang Liu |
| 8 | Engineering the surface of Gd2O3 nanoplates for improved T1-weighted magnetic resonance imaging | 期刊论文 | Cai Wen;Zhang Yang;Wang Junqing;Wang Zhiyong;Tian Ye;Liu Heng;Pan Hongzhi;Fu Li;Chen Wei;Wu Chunsheng;Wang Xiaoyong;Liu Gang |
| 9 | Vesicular Antibodies for Immunotherapy: The Blooming Intersection of Nanotechnology and Biotechnology | 期刊论文 | En Ren;Xin Pang;Zhao Lei;Gang Liu |
| 10 | A Single-step Multi-level Supramolecular System for Cancer Sonotheranostics | 期刊论文 | Huirong Lin;Shuang Li;Junqing Wang;Chengchao Chu;Yang Zhang;Xin Pang;Peng Lv;Xiaoyong Wang;Qingliang Zhao;Junjie Chen;Hongmin Chen;Wen Liu;Xiaoyuan Chen;Gang Liu |
| 11 | Artificial nanocage-based 3D framework platforms: From construction design to biomedical applications | 期刊论文 | Zhixiang Lu;Shuang Bai;Yesi Shi;Dazhuang Xu;Chengchao Chu;Gang Liu |
| 12 | Genetically Engineered Cellular Membrane Vesicles as Tailorable Shells for Therapeutics. | 期刊论文 | En Ren;Chao Liu;Peng Lv;Junqing Wang;Gang Liu |
| 13 | Biosynthetic magnetic nanocages: towards effective and safe magneto-catalytic cancer therapy | 期刊论文 | Gan Lin;Yang Zhang;Gang Liu |
| 14 | A Nanovaccine for Antigen Self-presentation and Immunosuppression Reversal as a Personalized Cancer Immunotherapy Strategy | 期刊论文 | Chao Liu;Xue Liu;Xinchu Xiang;Xin Pang;Siyuan Chen;Yunming Zhang;En Ren;Lili Zhang;Xuan Liu;Peng Lv;Xiaoyong Wang;Wenxin Luo;Ningshao Xia;Xiaoyuan Chen;Gang Liu |
| 15 | Tumor Microenvironment-Triggered MoS2@GA-Fe Nanoreactor: A Self-Rolling Enhanced Chemodynamic Therapy and Hydrogen Sulfide Treatment for Hepatocellular Carcinoma | 期刊论文 | Huili Zheng;Baoxin Ma;Yesi Shi;Qixuan Dai;Dongsheng Li;En Ren;Jing Zhu;Jianming Liu;Hu Chen;Zhenyu Yin;Chengchao Chu;Xiaomin Wang;Gang Liu |
| 16 | Vesicular antibodies: A bioactive multifunctional combination platform for targeted therapeutic delivery and cancer immunotherapy | 期刊论文 | Xue Liu;Chao Liu;Zizheng Zheng;Siyuan Chen;Xin Pang;Xinchu Xiang;Jixian Tang;En Ren;Yuanzhi Chen;Min You;Xiaoyong Wang;Xiaoyuan Chen;Wenxin Luo;Gang Liu;Ningshao Xia |
| 17 | A superstable homogeneous lipiodol-ICG formulation for locoregional hepatocellular carcinoma treatment | 期刊论文 | Hu Chen;Hongwei Cheng;Qixuan Dai;Yi Cheng;Yang Zhang;Dengfeng Li;Yang Sun;Jingsong Mao;Ke Ren;Chengchao Chu;Gang Liu |
| 18 | Mineral iron based Self-assembling: Bridging the Small Molecular Drugs and Transformative Application | 期刊论文 | En Ren;Chengchao Chu;Xin Pang;Peng Lv;Zhao Lei;Gang Liu |
| 19 | Cell membrane-derived biomimetic nanodecoys for viruses | 期刊论文 | Xuan Liu;Dengfeng Li;Gang Liu |
| 20 | Photo-excitable hybrid nanocomposites for image-guided photo/TRAIL synergistic cancer therapy | 期刊论文 | Gan Lin;Yang Zhang;Congqing Zhu;Chengchao Chu;Yesi Shi;Xin Pang;En Ren;Yayun Wu;Peng Mi;Haiping Xia;Xiaoyuan Chen;Gang Liu |
| 21 | Indocyanine Green-Based Nanodrugs: A Portfolio Strategy for Precision Medicine | 期刊论文 | Qixuan Dai;En Ren;Dazhuang Xu;Yun Zeng;Chuan Chen;Gang Liu |
| 22 | Repurposing ICG enables MR/PA imaging signal amplification and iron depletion for iron-overload disorders | 期刊论文 | Huirong Lin;Yu Zhou;Jiaming Wang;Huimeng Wang;Tianhong Yao;Hu Chen;Huili Zheng;Yang Zhang;En Ren;Lai Jiang;Chengchao Chu;Xiaoyuan Chen;Jingsong Mao;Fudi Wang;Gang Liu |
| 23 | Ultrasound-Switchable Nanozyme Augments Sonodynamic Therapy against Multidrug-Resistant Bacterial Infection | 期刊论文 | Sun Duo;Pang Xin;Cheng Yi;Ming Jiang;Xiang Sijin;Zhang Chang;Lv Peng;Chu Chengchao;Chen Xiaolan;Liu Gang;Zheng Nanfeng |
| 24 | Bioinspired Artificial Nanodecoys for Hepatitis B Virus | 期刊论文 | Xuan Liu;Lunzhi Yuan;Liang Zhang;Yalin Mu;Xiaoling Li;Chao Liu;Peng Lv;Yali Zhang;Tong Cheng;Quan Yuan;Ningshao Xia;Xiaoyuan Chen;Gang Liu |
| 25 | TRAIL-expressing cell membrane nanovesicles as an anti-inflammatory platform for rheumatoid arthritis therapy | 期刊论文 | Shi Yesi;Xie Fengfei;Rao Peishi;Qian Hongyan;Chen Rongjuan;Chen Hu;Li Dengfeng;Mu Dan;Zhang Lili;Lv Peng;Shi Guixiu;Zheng Li;Liu Gang |
| 26 | Bacteria-Responsive Nanoliposomes as Smart Sonotheranostics for Multidrug Resistant Bacterial Infections | 期刊论文 | Xin Pang;Qicai Xiao;Yi Cheng;En Ren;Lanlan Lian;Yang Zhang;Haiyan Gao;Xiaoyong Wang;Wingnang Leung;Xiaoyuan Chen;Gang Liu;Chuanshan Xu |
| 27 | Superstable homogeneous iodinated formulation technology: Revolutionizing transcatheter arterial chemoembolization | 期刊论文 | Hongwei Cheng;Xiaoming Yang;Gang Liu |
| 28 | Bio-engineered cell membrane nanovesicles as precision theranostics for perihilar cholangiocarcinoma | 期刊论文 | Zhang Xiaojie;Zhang Yang;Zhang Yunming;Lv Peng;Zhang Pengfei;Chu Chengchao;Mao Jingsong;Wang Xiaoyong;Li Wengang;Liu Gang |
| 29 | Tumor microenvironment-responsive ultra-small-nanodrug generators with enhanced tumor delivery and penetration | 期刊论文 | Pengfei Zhang;Junqing Wang;Hu Chen;Lei Zhao;Binbin Chen;Chengchao Chu;Heng Liu;Zainen Qin;Jingyi Liu;Yuanzhi Tan;Xiaoyuan Chen;Gang Liu |
| 30 | Noninvasive magnetic resonance/photoacoustic imaging for photothermal therapy response monitoring | 期刊论文 | Jing Ye;Guifeng Fu;Xiaohui Yan;Jingyi Liu;Xiaoyong Wang;Liang Cheng;Fan Zhang;Phillip Zhe Sun;Gang Liu |
| 31 | A Self-Assembled alpha-Synuclein Nanoscavenger for Parkinson's Disease | 期刊论文 | Liu Jingyi;Liu Chao;Zhang Jinfeng;Zhang Yunming;Liu Keyin;Song Ju-Xian;Sreenivasmurthy Sravan Gopalkrishnashetty;Wang Ziying;Shi Yesi;Chu Chengchao;Zhang Yang;Wu Caisheng;Deng Xianhua;Liu Xingyang;Song Jing;Zhuang Rongqiang;Huang Shugiong;Zhang Pengfei;Li Min;Wen Lei;Zhang Yun Wu;Liu Gang |
| 32 | Multi-responsive Bottlebrush-Like Unimolecules Self-Assembled Nano-Riceball for Synergistic Sono-Chemotherapy | 期刊论文 | Xiaoxiao Shi;Yang Zhang;Ye Tian;Shuyu Xu;En Ren;Shuang Bai;Xiaoyuan Chen;Chengchao Chu;Zhigang Xu;Gang Liu |
| 33 | Chapter 16: Nanotheranostics-based Imaging for Cancer Treatment Monitoring | 专著 | Tianxing Miao;Rachael A. Oldinski;Gang Liu;Xiaoyuan Chen |
| 34 | Sonoactivated Chemodynamic Therapy: A Robust ROS Generation Nanotheranostic Eradicates Multidrug-Resistant Bacterial Infection | 期刊论文 | Song Menglin;Cheng Yi;Tian Ye;Chu Chengchao;Zhang Chang;Lu Zhixiang;Chen Xiaoyuan;Pang Xin;Liu Gang |
| 35 | Metal-organic frameworks nanoswitch: Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference | 期刊论文 | Gan Lin;Yang Zhang;Long Zhang;Junqing Wang;Ye Tian;Wen Cai;Shangui Tang;Chengchao Chu;JiaJing Zhou;Peng Mi;Xiaoyuan Chen;Gang Liu |
| 36 | Photoacoustic Imaging-Trackable Magnetic Microswimmers for Pathogenic Bacterial Infection Treatment | 期刊论文 | Xie Lisi;Pang Xin;Yan Xiaohui;Dai Qixuan;Lin Huirong;Ye Jing;Cheng Yi;Zhao Qingliang;Ma Xing;Zhang Xianzhong;Liu Gang;Chen Xiaoyuan |
| 37 | Zinc(II)-dipicolylamine Coordination Nanotheranostics: Toward Synergistic Nanomedicine by Combined Photo/gene Therapy | 期刊论文 | Chengchao Chu;En Ren;Yunming Zhang;Jingwen Yu;Huirong Lin;Xin Pang;Yang Zhang;Heng Liu;Zaineng Qin;Yi Cheng;Xiaoyong Wang;Wei Li;Xiangjian Kong;Xiaoyuan Chen;Gang Liu |
| 38 | Chapter 19: Theranostic nanoparticles as imaging agents for siRNA delivery | 专著 | Zhe Wang;Junqing Wang;Gang Liu |
| 39 | Eumelanin-Fe3O4 hybrid Nanoparticles for Enhanced MR/PA Imaging-assisted Local Photothermolysis | 期刊论文 | Junqing Wang;Heng Liu;Yu Liu;Chengchao Chu;Youyuan Yang;Yun Zeng;Weiguo Zhang;Gang Liu |
| 40 | Nano-Medicine for Thrombosis: A Precise Diagnosis and Treatment Strategy | 期刊论文 | Min Su;Qixuan Dai;Chuan Chen;Yun Zeng;Chengchao Chu;Gang Liu |
| 41 | Organic Sonosensitizers for Sonodynamic Therapy: From Small Molecules and Nanoparticles toward Clinical Development. | 期刊论文 | Dong Li;Yang Yang;Dengfeng Li;Jie Pan;Chengchao Chu;Gang Liu |
| 42 | Imaging Nano-Bio Interactions in Kidney: Toward a Better Understanding of Nanoparticle Clearance | 期刊论文 | Junqing Wang;Gang Liu |
| 43 | Multimodal Photoacoustic Imaging-Guided Regression of Corneal Neovascularization: A Non-invasive and Safe Strategy | 期刊论文 | Chengchao Chu;Jingwen Yu;En Ren;Shangkun Ou;Yunming Zhang;Yiming Wu;Han Wu;Yang Zhang;Jing Zhu;Qixuan Dai;Xiaoyong Wang;Qingliang Zhao;Wei Li;Zuguo Liu;Xiaoyuan Chen;Gang Liu |
| 44 | Surface engineering of oncolytic adenovirus for a combination of immune checkpoint blockade and virotherapy | 期刊论文 | Peng Lv;Xiaomei Chen;Shiying Fu;En Ren;Chao Liu;Xuan Liu;Lai Jiang;Yun Zeng;Xiaoyong Wang;Gang Liu |
| 45 | Ultrasound activated nanosensitizers for sonodynamic therapy and theranostics | 期刊论文 | Lei Li;Huirong Lin;Dengfeng Li;Yun Zeng;Gang Liu |
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