核受体/间质蛋白酶（matriptase）在闽台高发恶性肿瘤发病和防治中的作用与机制研究
U1405229
2014
H1802.肿瘤发生
张晓坤
联合基金项目
教授
厦门大学
254万元
肝癌;前列腺癌;蛋白水解酶;光动力学疗法;核受体
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Binding characterization, synthesis and biological evaluation of RXR alpha antagonists targeting the coactivator binding site | 期刊论文 | Xu Dingyu;Guo Shangjie;Chen Ziwen;Bao Yuzhou;Huang Fengyu;Xu Dan;Zhang Xindao;Zeng Zhiping;Zhou Hu;Zhang Xiaokun;Su Ying |
| 2 | Rapid killing of bacteria by a new type of photosensitizer | 期刊论文 | Zhang Yaxin;Zheng Ke;Chen Zhuo;Chen Jincan;Hu Ping;Cai Linrong;Iqbal Zafar;Huang Mingdong |
| 3 | Photodynamic Oncotherapy Mediated by Gonadotropin-Releasing Hormone Receptors | 期刊论文 | Xu Peng;Jia Yuhua;Yang Yongshuai;Chen Jincan;Hu Ping;Chen Zhuo;Huang Mingdong |
| 4 | Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy | 期刊论文 | Hu Mengjie;Luo Qiang;Alitongbieke Gulimiran;Chong Shuyi;Xu Chenting;Xie Lei;Chen Xiaohui;Zhang Duo;Zhou Yuqi;Wang Zhaokai;Ye Xiaohong;Cai Lijun;Zhang Fang;Chen Huibin;Jiang Fuquan;Fang Hui;Yang Shanjun;Liu Jie;Diaz-Meco Maria T.;Su Ying;Zhou Hu;Moscat Jorge;Zhang Xiao-kun |
| 5 | NSC-640358 acts as RXR alpha ligand to promote TNF alpha-mediated apoptosis of cancer cell | 期刊论文 | Chen Fan;Chen Jiebo;Lin Jiacheng;Xu Lin;Zeng Zhiping;Chen Liqun;Huang Mingfeng;Hu Mengjie;Ye Xiaohong;Zhou Yuqi;Wang Guanghui;Su Ying;Zhang Xiao-kun;Zhou Hu;Chen Fan;Cheltsov Anton V.;Chen Ya;Su Ying;Zhang Xiao-kun;Zhang Long;Zhou Fangfang;Zhang XK;Zhou hu |
| 6 | Household light source for potent photo-dynamic antimicrobial effect and wound healing in an infective animal model. | 期刊论文 | Ullah Azeem;Zhang Yuxiang;Iqbal Zafar;Zhang Yaxin;Wang Dong;Chen Jincan;Hu Ping;Chen Zhuo;Huang Mingdong |
| 7 | Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo | 期刊论文 | Zheng Ke;Li Rui;Zhou Xiaolei;Hu Ping;Zhang Yaxin;Huang Yunmei;Chen Zhuo;Huang Mingdong |
| 8 | A long-acting PAI-1 inhibitor reduces thrombus formation | 期刊论文 | Peng Shuangzhou;Xue Guangpu;Gong Lihu;Fang Chao;Chen Jingfei;Yuan Cai;Chen Zhuo;Yao Lishan;Furie Bruce;Huang Mingdong |
| 9 | Near-infrared-triggered antibacterial and antifungal photodynamic therapy based on lanthanide-doped upconversion nanoparticles. | 期刊论文 | Zhang Yuxiang;Huang Ping;Wang Dong;Chen Jincan;Liu Wenzhen;Hu Ping;Huang Mingdong;Chen Xueyuan;Chen Zhuo |
| 10 | Targeting truncated RXR alpha for cancer therapy | 期刊论文 | Zhang Xiaokun;Zhou Hu;Su Ying |
| 11 | A novel purification procedure for recombinant human serum albumin expressed in Pichia pastoris. | 期刊论文 | Li Shijie;Li Linlin;Chen Zhuo;Xue Guangpu;Jiang Longguang;Zheng Ke;Chen Jincan;Li Rui;Yuan Cai;Huang Mingdong |
| 12 | 3‐Cl‐AHPC inhibits pro‐HGF maturation by inducing matriptase/HAI‐1 complex formation | 期刊论文 | Fang Ye;Shuang Chen;Xingxing Liu;Xiaohong Ye;Keqi Wang;Zhiping Zeng;Ying Su;Xiao-kun Zhang;Hu Zhou |
| 13 | Modulation of the Nur77-Bcl-2 apoptotic pathway by p38 alpha MAPK | 期刊论文 | Liu Jie;Wang Guang-Hui;Bao Yuzhou;Hu Mengjie;Zhou Yu-Qi;Li Mingyu;Jiang Fuquan;Zhou Hu;Zhang Xiao-Kun;Duan Ying-Hui;Dai Yi;Yao Xin-Sheng;Zhang Xiao-Kun |
| 14 | Recent Progress in the Design and Discovery of RXR Modulators Targeting Alternate Binding Sites of the Receptor | 期刊论文 | Ying Su;Zhiping Zeng;Ziwen Chen;Dan Xu;Weidong Zhang;Xiao-kun Zhang |
| 15 | Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy. | 期刊论文 | Hu Mengjie;Alitongbieke Gulimiran;Su Ying;Zhou Hu;Zhang Xiao-Kun |
| 16 | RXRalpha Nitro-ligand Z-10 and Its Optimized Derivative Z-36 Reduce beta-amyloid Plaques in AD Mouse Model. | 期刊论文 | Ren Gaoang;Bao Wei;Zeng Zhiping;Zhang Weidong;Shang Ce;Wang Maosi;Su Ying;Zhang Xiao-Kun;Zhou Hu |
| 17 | Smart Photosensitizer: Tumor-Triggered Oncotherapy by Self-Assembly Photodynamic Nanodots. | 期刊论文 | Jia Yuhua;Li Jinyu;Chen Jincan;Hu Ping;Jiang Longguang;Chen Xueyuan;Huang Mingdong;Chen Zhuo;Xu Peng |
| 18 | Sub-5 nm lanthanide-doped lutetium oxyfluoride nanoprobes for ultrasensitive detection of prostate specific antigen | 期刊论文 | Xu Jin;Zhou Shanyong;Tu Datao;Zheng Wei;Huang Ping;Li Renfu;Chen Xueyuan;Xu Jin;Chen Zhuo;Huang Mingdong;Chen Xueyuan;Xu Jin;Chen Xueyuan |
| 19 | An ELISA method detecting the active form of suPAR | 期刊论文 | Zhou Xiaolei;Xu Mingming;Huang Hailong;Mazar Andrew;Iqbal Zafar;Yuan Cai;Huang Mingdong |
| 20 | Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXR alpha | 期刊论文 | Chen Liqun;Aleshin Alexander E.;Alitongbieke Gulimiran;Zhou Yuqi;Zhang Xindao;Ye Xiaohong;Hu Mengjie;Ren Gaoang;Chen Ziwen;Ma Yue;Zhang Duo;Liu Shuai;Gao Weiwei;Cai Lijun;Wu Lingjuan;Zeng Zhiping;Jiang Fuquan;Liu Jie;Zhou Hu;Cadwell Gregory;Liddington Robert C.;Su Ying;Zhang Xiao-kun |
| 21 | Honokiol sensitizes breast cancer cells to TNF-alpha induction of apoptosis by inhibiting Nur77 expression | 期刊论文 | Xie Lei;Jiang Fuquan;Zhang Xindao;Alitongbieke Gulimiran;Shi Xinlei;Meng MinJun;Xu Yiming;Wang Jing;Cai Lijun;Zhou Yunxia;Xu Yang;Su Ying;Liu Jie;Zeng Zhiping;Wang Guanghui;Zhou Hu;Chen Quan Cheng;Zhang Xiao-kun |
| 22 | Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding | 期刊论文 | Yuan Cai;Li Rui;Liu Min;Jiang Longguang;Luo Zhipu;Huang Mingdong;Yuan Cai;Jurgensen Henrik J.;Engelholm Lars H.;Behrendt Niels;Engelholm Lars H.;Jiang Longguang;Huang Mingdong |
| 23 | Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier | 期刊论文 | Bag Partha Pratim;Wang Dong;Chen Zhuo;Cao Rong |
| 24 | Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy | 期刊论文 | Hu Mengjie;Luo Qiang;Alitongbieke Gulimiran;Chong Shuyi;Xu Chenting;Xie Lei;Chen Xiaohui;Zhang Duo;Zhou Yuqi;Wang Zhaokai;Ye Xiaohong;Cai Lijun;Zhang Fang;Chen Huibin;Jiang Fuquan;Fang Hui;Yang Shanjun;Liu Jie;Diaz-Meco Maria T.;Su Ying;Zhou Hu;Moscat Jorge;Zhang Xiao-kun |
| 25 | Binding characterization, synthesis and biological evaluation of RXR alpha antagonists targeting the coactivator binding site | 期刊论文 | Xu Dingyu;Guo Shangjie;Chen Ziwen;Bao Yuzhou;Huang Fengyu;Xu Dan;Zhang Xindao;Zeng Zhiping;Zhou Hu;Zhang Xiaokun;Su Ying |
| 26 | Modulation of the Nur77-Bcl-2 apoptotic pathway by p38 alpha MAPK | 期刊论文 | Liu Jie;Wang Guang-Hui;Bao Yuzhou;Hu Mengjie;Zhou Yu-Qi;Li Mingyu;Jiang Fuquan;Zhou Hu;Zhang Xiao-Kun;Duan Ying-Hui;Dai Yi;Yao Xin-Sheng;Zhang Xiao-Kun |
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