柯萨奇病毒A10优势中和抗体的表位结构与作用机制研究
81801646
2018
H1111.疫苗和免疫预防
徐龙发
青年科学基金项目
厦门大学
21万元
中和表位;Cryo-EM结构;中和作用;柯萨奇病毒A10;单克隆抗体
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Development of an efficient neutralization assay for Coxsackievirus A10 | 期刊论文 | Liu Dongxiao;Xu Longfa;Zhu Rui;Yin Zhichao;Lin Yu;Hou Wangheng;Li Shuxuan;He Shuizhen;Cheng Tong;Xia Ningshao |
| 2 | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization | 期刊论文 | Zheng Qingbing;Zhu Rui;Xu Longfa;He Maozhou;Yan Xiaodong;Liu Dongxiao;Yin Zhichao;Wu Yangtao;Li Yongchao;Yang Lisheng;Hou Wangheng;Li Shuxuan;Li Zizhen;Chen Zhenqin;Li Zhihai;Yu Hai;Gu Ying;Zhang Jun;Baker Timothy S;Zhou Z Hong;Graham Barney S;Cheng Tong;Li Shaowei;Xia Ningshao |
| 3 | 柯萨奇病毒A组16型单克隆抗体16E1及其制备方法 | 专利 | 程通;叶祥忠;毛群颖;徐龙发;梁争论;高帆;韩金乐;夏宁邵 |
| 4 | Development of A Neonatal Mouse Model for Coxsackievirus B1 Antiviral Evaluation | 期刊论文 | Yin Zhichao;Wu Yuanyuan;Zhu Rui;Xu Longfa;Lin Yu;Yang Hongwei;Fu Wenkun;Huang Qiongzi;Zhang Dongqing;Wang Jue;Wang Wei;Wang Yingbin;Cheng Tong;Xia Ningshao |
| 5 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating | 期刊论文 | Xu Longfa;Zheng Qingbing;Zhu Rui;Yin Zhichao;Yu Hai;Lin Yu;Wu Yuanyuan;He Maozhou;Huang Yang;Jiang Yichao;Sun Hui;Zha Zhenghui;Yang Hongwei;Huang Qiongzi;Zhang Dongqing;Chen Zhenqin;Ye Xiangzhong;Han Jinle;Yang Lisheng;Liu Che;Que Yuqiong;Fang Mujin;Gu Ying;Zhang Jun;Luo Wenxin;Zhou Z. Hong;Li Shaowei;Cheng Tong... |
| 6 | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. | 期刊论文 | He Maozhou;Xu Longfa;Zheng Qingbing;Zhu Rui;Yin Zhichao;Zha Zhenghui;Lin Yu;Yang Lisheng;Huang Yang;Ye Xiangzhong;Li Shuxuan;Hou Wangheng;Wu Yangtao;Han Jinle;Liu Dongxiao;Li Zekai;Chen Zhenqin;Yu Hai;Que Yuqiong;Wang Yingbin;Yan Xiaodong;Zhang Jun;Gu Ying;Zhou Z Hong;Cheng Tong;Li Shaowei;Xia Ningshao |
| 7 | 抗柯萨奇病毒A6型病毒的单克隆抗体及其应用 | 专利 | 程通;徐龙发;朱瑞;尹志超;叶祥忠;罗文新;夏宁邵 |
| 8 | 针对柯萨奇病毒B1型的单克隆抗体及其用途 | 专利 | 程通;徐龙发;朱瑞;尹志超;王玮;付文锟;叶祥忠;夏宁邵 |
| 9 | 人肠道病毒的广谱亲和表位多肽、抗体及其用途 | 专利 | 程通;徐龙发;李志群;郑郡;杨立生;何德磊;叶祥忠;夏宁邵 |
| 10 | A bispecific broadly neutralizing antibody against enterovirus 71 and coxsackievirus A16 with therapeutic potential | 期刊论文 | Zhou Bing;Xu Longfa;Zhu Rui;Tang Jixian;Wu Yangtao;Su Ruopeng;Yin Zhichao;Liu Dongxiao;Jiang Yichao;Wen Can;You Min;Dai Linlin;Lin Yu;Chen Yuanzhi;Yang Haijie;An Zhigiang;Fan Changfa;Cheng Tong;Luo Wenxin;Xia Ningshao |
| 11 | 厦门市健康人群肠道病毒D68型血清流行病学调查 | 期刊论文 | 林雨;朱瑞;吴圆圆;徐龙发;尹志超;杨宏伟;郑清炳;阙玉琼;叶江辉;何水珍;程通;夏宁邵 |
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