动态超分子调控型CRISPR/Cas9基因编辑递送系统的构建及应用

32000992
2020
C1007.纳米生物学
李博文
青年科学基金项目
助理研究员
浙江大学
24万元
刺激响应释放;高分子纳米载体;基因编辑;基因治疗;小分子调控
2021-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A self-assembly nano-prodrug for triple-negative breast cancer combined treatment by ferroptosis therapy and chemotherapy 期刊论文 Yuan Chen;Zhuo Yao;Peilian Liu;Qida Hu;Yong Huang;Li Ping;Fu Zhang;Honglin Tang;Tao Wan;Yuan Ping;Bowen Li
2 Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug 期刊论文 Yong Huang;Yi Lin;Bowen Li;Fu Zhang;Chenyue Zhan;Xin Xie;Zhuo Yao;Chongzhi Wu;Yuan Ping;Jianliang Shen
3 A small-molecule self-assembled nanodrug for combination therapy of photothermal-differentiation-chemotherapy of breast cancer stem cells 期刊论文 Xin Xie;Kailong Jiang;Bowen Li;Shenglei Hou;Honglin Tang;Baihao Shao;Yuan Ping;Qiqing Zhang
4 Overcoming ROS Resistance of Photodynamic Therapy with Self‐Assembled Nano‐Prodrugs for Efficient Triple‐Negative Breast Cancer 期刊论文 Bowen Li;Jianwu Tian;Xin Xie;Fu Zhang;Chongzhi Wu;Yi Shan;Guobin Qi;Wentao Song;Yuan Ping;Bin Liu
5 A Self‐Assembly Nano‐Prodrug for Combination Therapy in Triple‐Negative Breast Cancer Stem Cells 期刊论文 Chongzhi Wu;Fu Zhang;Bowen Li;Zhiyao Li;Xin Xie;Yong Huang;Zhuo Yao;Yuan Chen;Yuan Ping;Weidong Pan
6 A Self‐Assembly Combined Nano‐Prodrug to Overcome Gemcitabine Chemo‐Resistance of Pancreatic Tumors 期刊论文 Zhuo Yao;Qida Hu;Piaopiao Jin;Bowen Li;Yong Huang;Fu Zhang;Meng Wang;Junming Huang;Jing Huang;Shiyi Shao;Xinyu Zhao;Yuan Ping;Tingbo Liang
7 A biomimetic nanodrug for enhanced chemotherapy of pancreatic tumors 期刊论文 Fu Zhang;Qida Hu;Bowen Li;Yong Huang;Meng Wang;Shiyi Shao;Honglin Tang;Zhuo Yao;Yuan Ping;Tingbo Liang
8 Membrane-camouflaged supramolecular nanoparticles for co-delivery of chemotherapeutic and molecular-targeted drugs with siRNA against patient-derived pancreatic carcinoma 期刊论文 Honglin Tang;Yanan Xue;Bowen Li;Xiaojie Xu;Fu Zhang;Jiajing Guo;Qijun Li;Tingting Yuan;Yuan Chen;Yubin Pan;Yuan Ping;Da Li
9 Delivery of a system xc- inhibitor by a redox-responsive levodopa prodrug nanoassembly for combination ferrotherapy. 期刊论文 Huhu Xin;Yong Huang;Honglin Tang;Yuan Chen;Hongguang Xia;Fu Zhang;Bowen Li;Yuan Ping
10 Targeted delivery of PROTAC-based prodrug activated by bond-cleavage bioorthogonal chemistry for microneedle-assisted cancer therapy 期刊论文 Jing Huang;Zhuo Yao;Bowen Li;Yuan Ping
11 Supramolecular genome editing: targeted delivery and endogenous activation of CRISPR/Cas9 by dynamic host-guest recognition. 期刊论文 Bowen Li;Qing Li;Zidan Qi;Zhiyao Li;Xiaojie Yan;Yuan Chen;Xiaojie Xu;Qi Pan;Yuxuan Chen;Feihe Huang;Yuan Ping
12 Tumor-overexpressed enzyme responsive amphiphiles small molecular self-assembly nano-prodrug for the chemo-phototherapy against non-small-cell lung cancer 期刊论文 Peilian Liu;Yong Huang;Chenyue Zhan;Fu Zhang;Chuansen Deng;Yongmei Jia;Tao Wan;Sheng Wang;Bowen Li
13 A biomimetic nanodrug self-assembled from small molecules for enhanced ferroptosis therapy 期刊论文 Xueming Xu;Yuan Chen;Jinyong Gui;Peilian Liu;Yong Huang;Yuan Ping;Bowen Li
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