蛋白激酶Plk1新型结合蛋白的鉴定及其在有丝分裂中的作用机制研究
31771499
2017
C0704.细胞命运及重编程
汪方炜
面上项目
教授
浙江大学
61万元
蛋白激酶Plk1;G2/M转折;周期素依赖性蛋白激酶(CDK);有丝分裂;染色体整列
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Aurora B kinase activity-dependent and -independent functions of the chromosomal passenger complex in regulating sister chromatid cohesion | 期刊论文 | Yi Qi;Chen Qinfu;Yan Haiyan;Zhang Miao;Liang Cai;Xiang Xingfeng;Pan Xuan;Wang Fangwei |
| 2 | Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation | 期刊论文 | Chen Qinfu;Zhang Miao;Pan Xuan;Yuan Xueying;Zhou Linli;Yan Lu;Zeng Ling-Hui;Xu Junfen;Yang Bing;Zhang Long;Huang Jun;Lu Weiguo;Fukagawa Tatsuo;Wang Fangwei;Yan Haiyan |
| 3 | Histone H2A phosphorylation recruits topoisomerase II alpha to centromeres to safeguard genomic stability | 期刊论文 | Zhang Miao;Liang Cai;Chen Qinfu;Yan Haiyan;Xu Junfen;Zhao Hongxia;Yuan Xueying;Liu Jingbo;Lin Shixian;Lu Weiguo;Wang Fangwei |
| 4 | WAC Promotes Polo-like Kinase 1 Activation for Timely Mitotic Entry | 期刊论文 | Qi Feifei;Chen Qinfu;Chen Hongxia;Yan Haiyan;Chen Binbin;Xiang Xingfeng;Liang Cai;Yi Qi;Zhang Miao;Cheng Hankun;Zhang Zhenlei;Huang Jun;Wang Fangwei |
| 5 | HP1 links centromeric heterochromatin to centromere cohesion in mammals | 期刊论文 | Yi Qi;Chen Qinfu;Liang Cai;Yan Haiyan;Zhang Zhenlei;Xiang Xingfeng;Zhang Miao;Qi Feifei;Zhou Linli;Wang Fangwei |
| 6 | Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation | 期刊论文 | Liang Cai;Zhang Zhenlei;Chen Qinfu;Yan Haiyan;Zhang Miao;Zhou Linli;Xu Junfen;Lu Weiguo;Wang Fangwei |
| 7 | A positive feedback mechanism ensures proper assembly of the functional inner centromere during mitosis in human cells | 期刊论文 | Liang Cai;Zhang Zhenlei;Chen Qinfu;Yan Haiyan;Zhang Miao;Xiang Xingfeng;Yi Qi;Pan Xuan;Cheng Hankun;Wang Fangwei |
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