Dscam转录本5'端高度多样性的发现和调控机制及其功能研究
31630089
2016
C0507.核酸生物化学
金勇丰
重点项目
教授
浙江大学
269万元
剪接机制;RNA可变剪接;唐氏综合症细胞黏附分子;组合调控;选择性启动子
2017-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Role and convergent evolution of competing RNA secondary structures in mutually exclusive splicing | 期刊论文 | Yuan Yue;Shouqing Hou;Xiu Wang;Leilei Zhan;Guozheng Cao;Guoli Li;Yang Shi;Peng Zhang;Weiling Hong;Hao Lin;Baoping Liu;Feng Shi;Yun Yang;Yongfeng Jin |
| 2 | A chelicerate-specific burst of nonclassical Dscam diversity | 期刊论文 | Guozheng Cao;Yang Shi;Jian Zhang;Hongru Ma;Shouqing Hou;Haiyang Dong;Weiling Hong;Shuo Chen;Hao Li;Yandan Wu;Pengjuan Guo;Xu Shao;Bingbing Xu;Feng Shi;Yijun Meng;Yongfeng Jin |
| 3 | Mutually exclusive alternative splicing of pre-mRNAs | 期刊论文 | Yongfeng Jin;Haiyang Dong;Yang Shi;Lina Bian |
| 4 | Complex RNA Secondary Structures Mediate Mutually Exclusive Splicing of Coleoptera Dscam1 | 期刊论文 | Haiyang Dong;Lei Li;Xiaohua Zhu;Jilong Shi;Ying Fu;Shixin Zhang;Yang Shi;Bingbing Xu;Jian Zhang;Feng Shi;Yongfeng Jin |
| 5 | Role of RNA secondary structures in regulating Dscam alternative splicing | 期刊论文 | Bingbing Xu;Yang Shi;Yandan Wu;Yijun Meng;Yongfeng Jin |
| 6 | Revisiting Dscam diversity: lessons from clustered protocadherins | 期刊论文 | Yongfeng Jin;Hao Li |
| 7 | RNA structures in alternative splicing and back-splicing | 期刊论文 | Bingbing Xu;Yijun Meng;Yongfeng Jin |
| 8 | Hidden RNA pairings counteract the “first-come,first-served” splicing principle to drive stochastic choice in Dscam1 splice variants | 期刊论文 | Haiyang Dong;Bingbing Xu;Pengjuan Guo;Jian Zhang;Xi Yang;Lei Li;Ying Fu;Jilong Shi;Shixin Zhang;Yanda Zhu;Yang Shi;Fengyan Zhou;Lina Bian;Wendong You;Feng Shi;Xiaofeng Yang;Jianhua Huang;Haihuai He;Yongfeng Jin |
| 9 | Competing RNA pairings in complex alternative splicing of a 3′variable region | 期刊论文 | Huawei Pan;Yang Shi;Shuo Chen;Yun Yang;Yuan Yue;Leiei Zhan;Lanzhi Dai;Haiyang Dong;Weiling Hong;Feng Shi;Yongfeng Jin |
| 10 | Chelicerata sDscam isoforms combine homophilic specificities to define unique cell recognition | 期刊论文 | Fengyan Zhou;Guozheng Cao;Songjun Dai;Guo Li;Hao Li;Zhu Ding;Shouqing Hou;Bingbing Xu;Wendong You;Gil Wiseglass;Feng Shi;Xiaofeng Yang;Rotem Rubinstein;Yongfeng Jin |
| 11 | Intron-targeted mutagenesis reveals roles for Dscam1 RNA pairing architecture-driven splicing bias in neuronal wiring | 期刊论文 | Weiling Hong;Jian Zhang;Haiyang Dong;Yang Shi;Hongru Ma;Fengyan Zhou;Bingbing Xu;Ying Fu;Shixin Zhang;Shouqing Hou;Guo Li;Yandan Wu;Shuo Chen;Xiaohua Zhu;Wendong You;Feng Shi;Xiaofeng Yang;Zhefeng Gong;Jianhua Huang;Yongfeng Jin |
| 12 | RNA secondary structures in Dscam1 mutually exclusive splicing: unique evolutionary signature from the midge | 期刊论文 | Weiling Hong;Yang Shi;Bingbing Xu;Yongfeng Jin |
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