基于比率型光声探针的肿瘤特征分子功能可视化及早期胃癌诊断研究

91959123
2019
H2706.分子影像
史海斌
重大研究计划
教授
苏州大学
80万元
多模态成像;胃癌的早期诊断;比率光声型成像;基质金属蛋白酶;分子影像探针
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Alkaline Phosphatase-Controllable and Red Light-Activated RNA Modification Approach for Precise Tumor Suppression 期刊论文 Jing Fang;Yali Feng;Yuqi Zhang;Anna Wang;Jiachen Li;Chaoxiang Cui;Yirui Guo;Jinfeng Zhu;Zhengzhong Lv;Zhongheng Zhao;Chenjie Xu;Haibin Shi
2 基于多模态智能化分子影像探针的肿瘤精准诊疗及相关机制研究 奖励 史海斌;陈卫昌;汪勇;曾剑峰;朱然;栾富娟;程侠菊;何蕾
3 一种紫外光触发交联型近红外分子探针及其制备方法与应用 专利 史海斌;孙瑞
4 紫外光介导的纳米颗粒自组装聚集体、其制备方法和应用 专利 史海斌;高明远;程侠菊;孙瑞
5 Smart On-Site Immobilizable Near-Infrared II Fluorescent Nanoprobes for Ultra-Long-Term Imaging-Guided Tumor Surgery and Photothermal Therapy 期刊论文 Zhang Yuqi;Zhao Meng;Fang Jing;Shuyue Ye;Wang Anna;Zhao Yan;Cui Chaoxiang;He Lei;Shi Haibin
6 pH/reduction dual stimuli-triggered self-assembly of NIR theranostic probes for enhanced dual-modal imaging and photothermal therapy of tumors 期刊论文 Wang Anna;Mao Qiulian;Zhao Meng;Ye Shuyue;Fang Jing;Cui Chaoxiang;Zhao Yan;Zhang Yuqi;Zhang Yu;Shi Haibin
7 In Vivo Quantitative Assessment of Radiation Dose Based on Ratiometric Photoacoustic Imaging of Tumor Apoptosis 期刊论文 Fang Jing;Zhao Yan;Wang Anna;Zhang Yuqi;Cui Chaoxiang;Ye Shuyue;Mao Qiulian;Feng Yali;Li Jiachen;Xu Chenjie;Shi Haibin
8 一种肿瘤微环境H2O2响应交联型近红外分子探针及其应用 专利 史海斌;高银佳
9 碱性磷酸酶响应型分子探针及其应用 专利 史海斌;赵梦;周如鸿
10 Building multipurpose nano-toolkit by rationally decorating NIR-II fluorophore to meet the needs of tumor diagnosis and treatment 期刊论文 Cui Chaoxiang;Li Jiachen;Fang Jing;Zhao Yan;Zhang Yuqi;Ye Shuyue;Wang Anna;Feng Yali;Mao Qiulian;Qin Hongni;Shi Haibin
11 Red light-initiated crosslinking of NIR probes to cytoplasmic RNA: an innovative strategy for prolonged imaging and unexpected tumor suppression 期刊论文 Ye Shuyue;Cui Chaoxiang;Cheng Xiaju;Zhao Meng;Mao Qiulian;Zhang Yuqi;Wang Anna;Fang Jing;Zhao Yan;Shi Haibin
12 紫外光介导的纳米颗粒自组装聚集体和应用 专利 史海斌;高明远;程侠菊;孙瑞
13 高稳定性近红外二区纳米荧光探针及其制备方法和应用 专利 史海斌;张誉荠
14 高稳定性近红外二区小分子荧光探针及其制备方法和应用 专利 史海斌;赵梦
15 叶酸修饰的金纳米颗粒及其制备方法与在制备放射增敏治疗药物中的应用 专利 史海斌;高明远;程侠菊;孙瑞
16 Endogenous ROS-mediated Covalent Immobilization of Gold Nanoparticles in Mitochondria: A “Sharp Sword” in Tumor Radiotherapy 期刊论文 Yan Zhao;Yali Feng;Jiachen Li;Chaoxiang Cui;Anna Wang;Jing Fang;Yuqi Zhang;Shuyue Ye;Qiulian Mao;Xiaoyan Wang;Haibin Shi
17 Sulfenic acid-mediated on-site-specific immobilization of mitochondrial-targeted NIR fluorescent probe for prolonged tumor imaging 期刊论文 Gao Yinjia;Sun Rui;Zhao Meng;Ding Jianan;Wang Anna;Ye Shuyue;Zhang Yuqi;Mao Qiulian;Xie Wei;Ma Guolin;Shi Haibin
18 Aggregation of Gold Nanoparticles Triggered by Hydrogen Peroxide-Initiated Chemiluminescence for Activated Tumor Theranostics 期刊论文 Mao Qiulian;Fang Jing;Wang Anna;Zhang Yuqi;Cui Chaoxiang;Ye Shuyue;Zhao Yan;Feng Yali;Li Jiachen;Shi Haibin
19 Real-Time Visualization of Embryonic Apoptosis Using a Near-Infrared Fluorogenic Probe for Embryo Development Evaluation 期刊论文 He Lei;Ye Shuyue;Fang Jing;Zhang Yuqi;Cui Chaoxiang;Wang Anna;Zhao Yan;Shi Haibin
20 红光介导的核酸锚定型荧光探针及其制备方法和应用 专利 史海斌;叶舒岳
21 r-谷氨酰转肽酶响应型分子探针及其应用 专利 史海斌;赵梦
22 Protein sulfenic acid-mediated anchoring of gold nanoparticles for enhanced CT imaging and radiotherapy of tumors in vivo 期刊论文 Ding Jianan;Mao Qiulian;Zhao Meng;Gao Yinjia;Wang Anna;Ye Shuyue;Wang Xiaoyan;Xie Wei;Shi Haibin
23 A novel αvβ3 integrin-targeted NIR-II nanoprobe for multimodal imaging-guided photothermal therapy of tumor in vivo 期刊论文 Zhao Meng;Ding Jianan;Mao Qiulian;Zhang Yuqi;Gao Yinjia;Ye Shuyue;Qin Hongni;Shi Haibin
24 A Hydrogen Sulphide-responsive and Depleting Nanoplatform for Cancer Photodynamic Therapy 期刊论文 Zhang Yuqi;Fang Jing;Ye Shuyue;Zhao Yan;Wang Anna;Mao Qiulian;Cui Chaoxiang;Feng Yali;Li Jiachen;Li Sunao;Zhang Mingyang;Shi Haibin
25 Furin Enzyme and pH Synergistically Triggered Aggregation of Gold Nanoparticles for Activated Photoacoustic Imaging and Photothermal Therapy of Tumors 期刊论文 Cheng Xiaju;Zhou Xiuxia;Xu Jingwei;Sun Rui;Xia Huawei;Ding Jianan;Chin Y Eugene;Chai Zhifang;Shi Haibin;Gao Mingyuan
26 肿瘤多模态诊疗一体化探针相关基础研究 奖励 高明远;李桢;汪勇;史海斌;曾剑峰;文玲;高振宇;张少华;程侠菊
27 Assembly Transformation Jointly Driven by the LAP Enzyme and GSH Boosting Theranostic Capability for Effective Tumor Therapy 期刊论文 Wang Anna;Fang Jing;Ye Shuyue;Mao Qiulian;Zhao Yan;Cui Chaoxiang;Zhang Yuqi;Feng Yali;Li Jiachen;He Lei;Qiu Ling;Shi Haibin
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