基于酸碱微环境调控的腰椎间盘退变修复新技术的建立及其机制研究

91849114
2018
H0608.骨、关节、软组织退行性病变
杨惠林
重大研究计划
教授
苏州大学
50万元
微环境;钠氢交换体;椎间盘退变;修复;酸碱度
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Inhibitory effect of acetyl-11-keto-?-boswellic acid on titanium particle-induced bone loss by abrogating osteoclast formation and downregulating the ERK signaling pathway 期刊论文 Shi Jiawei;Gu Ye;Wang Yong;Bai Jiaxiang;Xiong Longbin;Tao Yunxia;Xue Yi;Xu Yaozeng;Yang Huilin;Ye Hongwei;Geng Dechun
2 FK506 Induces the TGF-beta 1/Smad 3 Pathway Independently of Calcineurin Inhibition to Prevent Intervertebral Disk Degeneration 期刊论文 Ge Jun;Wang Yingjie;Yan Qi;Wu Cenhao;Yu Hao;Yang Huilin;Zou Jun
3 The protein tyrosine kinase inhibitor, Genistein, delays intervertebral disc degeneration in rats by inhibiting the p38 pathway-mediated inflammatory response 期刊论文 Jun Ge;Quan Zhou;Xiaoqiang Cheng;Jiale Qian;Qi Yan;Cenhao Wu;Yufeng Chen;Huilin Yang;Jun Zou
4 Silk Fibroin Regulates Osteoconduction of Hydroxyapatite in Rat Spine Fusion Model 期刊论文 Cenhao Wu;Genlin Wang;Qi Yan;Jeffrey C Wang;Huilin Yang;Jun Zou
5 A selective CB2 agonist protects against the inflammatory response and joint destruction in collagen-induced arthritis mice 期刊论文 Bai Jiaxiang;Ge Gaoran;Wang Yijun;Zhang Wenhao;Wang Qing;Wang Wei;Guo Xiaobin;Yu Binqing;Xu Yaozeng;Yang Huilin;Zhu Xuesong;Wang Mingjun;Geng Dechun
6 Calcitonin inhibits intervertebral disc degeneration by regulating protein kinase C 期刊论文 Jun Ge;Xiaoqiang Cheng;Qi Yan;Cenhao Wu;Yingjie Wang;Hao Yu;Huilin Yang;Feng Zhou;Jun Zou
7 Therapeutic Efficacy Analysis of Talar Fracture Internal Fixation with Lateral Malleolar Osteotomy 期刊论文 Gang Liu;Jun Ge;Xiaohan Zheng;Cenhao Wu;Qi Yan;Huilin Yang;Jun Zou
8 Tea Polyphenol Attenuates Oxidative Stress-Induced Degeneration of Intervertebral Discs by Regulating the Keap1/Nrf2/ARE Pathway 期刊论文 Dawei Song;Jun Ge;Yingjie Wang;Qi Yan;Cenhao Wu;Hao Yu;Ming Yang;Huilin Yang;Jun Zou
9 The clinical effect of kyphoplasty using the extrapedicular approach in the treatment of thoracic osteoporotic vertebral compression fracture 期刊论文 Jun Ge;Xiaoqiang Cheng;Peng Li;Huilin Yang;Jun Zou
10 Puncture Intervertebral Disc Degeneration Model: A Standard on Rabbit 期刊论文 Wang Yingjie;Chen Jie;Ge Jun;Yan Qi;Wu Cenhao;Yu Hao;Yang Huilin;Zou Jun
11 Proximal femur lag screw placement based on bone mineral density determined by quantitative computed tomography 期刊论文 Gang Liu;Jun Ge;Xiaohan Zheng;Cenhao Wu;Qi Yan;Huilin Yang;Jun Zou
12 Selection of the Optimal Puncture Needle for Induction of a Rat Intervertebral Disc Degeneration Model 期刊论文 Qian Jiale;Ge Jun;Yan Qi;Wu Cenhao;Yang Huilin;Zou Jun
13 PMMA bone cement acts on the Hippo/YAP pathway to regulate CTGF and induce intervertebral disc degeneration 期刊论文 Jun Ge;Huilin Yang;Yufeng Chen;Qi Yan;Cenhao Wu;Jun Zou
14 Distribution of Modic changes in patients with low back pain and its related factors 期刊论文 Yufeng Chen;Jie Bao;Qi Yan;Cenhao Wu;Huilin Yang;Jun Zou
15 Resveratrol protects human nucleus pulposus cells from degeneration by blocking IL-6/JAK/STAT3 pathway 期刊论文 Wu Cenhao;Ge Jun;Yang Ming;Yan Qi;Wang Yingjie;Yu Hao;Yang Huilin;Zou Jun
16 IL-10 delays the degeneration of intervertebral discs by suppressing the p38 MAPK signaling pathway 期刊论文 Jun Ge;Qi Yan;Yingjie Wang;Xiaoqiang Cheng;Dawei Song;Cenhao Wu;Hao Yu;Huilin Yang;Jun Zou
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