基于表观遗传和免疫代谢调控的训练固有免疫记忆在新生儿脓毒症中的作用机制研究

81871594
2018
H1601.脓毒症
汪健
面上项目
教授
苏州大学
57万元
脓毒症;细胞代谢;表观遗传重编程;新生儿;训练固有免疫记忆
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 儿童脓毒症早期预警体系的建立及固有免疫调控研究 奖励 汪健;周慧婷;彭天庆;黄洁;陈正荣;许云云;陈旭勤;张雁云;赵赫;郭万亮;柏振江;李毅平;李嫣;王谦;曹戌
2 Cannabinoid receptor 2 promotes the intracellular degradation of HMGB1 via the autophagy-lysosome pathway in macrophage 期刊论文 Huiting Zhou;Rao Du;Gang Li;Zhenjiang Bai;Jin Ma;Chenmei Mao;Jian Wang;Huan Gui
3 Two-phase releasing immune-stimulating composite orchestrates protection against microbial infections 期刊论文 Zhao H;Lv XJ;Huang J;Huang SG;Zhou HT;Wang HR;Xu YY;Wang J H;Wang J;Liu Z
4 Induction of Trained Immunity Protects Neonatal Mice Against Microbial Sepsis by Boosting Both the Inflammatory Response and Antimicrobial Activity 期刊论文 Zhou HT;Lu XY;Huang J;Jordan P;Ma SR;Xu LQ;Hu FJ;Gui H;Zhao H;Bai ZJ;Redmond HP;Wang JH;Wang J
5 Activation of both TLR and NOD signaling confers host innate immunity-mediated protection against microbial infection 期刊论文 Zhou HT;Coveney AP;Wu M;Huang J;Blankson S;Zhao H;Leary PO;Bai ZJ;Li YP;Redmond HP;Wang J H;Wang J
6 儿童脓毒症早期预警诊疗体系的建立及相关固有免疫靶点研究 奖励 汪健;姚咏明;张雁云;陈旭勤;周慧婷;黄洁;许云云;陈正荣;赵赫
7 Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and tolerance 期刊论文 Jie Huang;Michael Ita;Huiting Zhou;He Zhao;Fara Hassan;Zhenjiang Bai;D. Peter O’Leary;Yiping Li;H. Paul Redmond;Jiang Huai Wang;Jian Wang
8 ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds 期刊论文 Zhao H;Huang J;Li Y;Lv X;Zhou H;Wang H;Xu Y;Wang C;Wang J;Liu Z
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