CBS-H2S硫巯基化修饰caspase-1对小胶质细胞NLRP3炎症小体的调控及其在帕金森病炎症中的作用
81870997
2018
H0912.神经退行性变及相关疾病
胡丽芳
面上项目
教授
苏州大学
56万元
硫巯基化修饰;炎症小体;小胶质细胞;帕金森病;胱硫醚-β-合成酶
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | alpha-synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson's disease | 期刊论文 | Tu Hai-Yue;Yuan Bao-Shi;Hou Xiao-Ou;Zhang Xiao-Jun;Pei Chong-Shuang;Ma Ya-Ting;Yang Ya-Ping;Fan Yi;Qin Zheng-Hong;Liu Chun-Feng;Hu Li-Fang |
| 2 | AMPK S-sulfuration contributes to H2S donors-induced AMPK phosphorylation and autophagy activation in dopaminergic cells | 期刊论文 | Hou Xiao-Ou;Tu Hai-Yue;Qian Hai-Chun;Li Qian;Yang Ya-Ping;Xu Guo-Qiang;Wang Fen;Liu Chun-Feng;Wang Ya-Li;Hu Li-Fang |
| 3 | Roles of microglial mitophagy in neurological disorders | 期刊论文 | Liu Yang;Wang Miao;Hou Xiao-Ou;Hu Li-Fang |
| 4 | Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson’s disease | 期刊论文 | Dong An-Qi;Yang Ya-Ping;Jiang Shu-Min;Yao Xiao-Yu;Qi Di;Mao Cheng-Jie;Cheng Xiao-Yu;Wang Fen;Hu Li-Fang;Liu Chun-Feng |
| 5 | Insights into the mechanism of thiol-triggered COS/H2S release from N-dithiasuccinoyl amines | 期刊论文 | Zhou Sheng-Chao;Mou Yu-Jie;Liu Miao;Du Qian;Ali Basharat;Ramprasad Jurupula;Qiao Chun-Hua;Hu Li-Fang;Ji Xing-Yue |
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