PM2.5致先心病中DNA甲基化调控及其作用机制

81870239
2018
H0203.先天性心脏病
姜岩
面上项目
教授
苏州大学
57万元
先天性心脏病（先心病）;PM2.5;多环芳烃受体;Serca2A;DNA甲基化
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 芳香烃受体与Wnt在心脏发育中的作用 期刊论文 夏颖;刘甜甜;滕忠坤;王建茗;陈涛;姜岩
2 Protein files of rat cardiomyocyte exposed to PM2.5 会议论文 Jianming Wang;Tiantian Liu;Zhongkun Teng;Tao Chen;Yan Jiang
3 Fine particulate matter induces heart defects via AHR/ROS-mediated endoplasmic reticulum stress 期刊论文 Mingxuan Zhang;Jin Chen;Yan Jiang;Tao Chen
4 Using Immunofluorescence to Detect PM2.5-induced DNA Damage in Zebrafish Embryo Hearts 期刊论文 Yujie Huang;Yizhou Tao;Chang Cai;Jin Chen;Cheng Ji;Stanley Aniagu;Yan Jiang;Tao Chen
5 Protective effects of Folic acid on the cardiac developmental toxicity of BaP 会议论文 Jianming Wang;Haobin Feng;Tao Chen;Yan Jiang
6 AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a] pyrene-induced heart defects and the protective effects of resveratrol 期刊论文 Yujie Huang;Jie Zhang;Yizhou Tao;Cheng Ji;Stanley Aniagu;Yan Jiang;Tao Chen
7 Genome-wide profiling of transcriptome and DNA methylome in human embryonic stem cells after PM2.5 exposure 会议论文 Tiantian Liu;Jiangming Wang;Ying Xia;Tao Chen;Yan Jiang
8 Synergistic protective effects of folic acid and resveratrol against fine particulate matter-induced heart malformations in zebrafish embryos. 期刊论文 Jin Chen;Mingxuan Zhang;Hongmei Zou;Stanley Aniagu;Yan Jiang;Tao Chen
9 PM2.5-induced extensive DNA methylation changes in the heart of zebrafish embryos and the protective effect of folic acid 期刊论文 Yan Jiang;Jianxiang Li;Fei Ren;Cheng Ji;Stanley Aniagu;Tao Chen
10 AHR-mediated ROS production contributes to the cardiac developmental toxicity of PM2.5 in zebrafish embryos 期刊论文 Fei Ren;Cheng Ji;Yujie Huang;Stanley Aniagu;Yan Jiang;Tao Chen
11 Aryl hydrocarbon receptor mediates the cardiac developmental toxicity of EOM from PM2.5 in P19 embryonic carcinoma cells 期刊论文 Tao Chen;Hongmei Jin;Huimin Wang;Yugang Yao;Stanley Aniagu;Jian Tong;Yan Jiang
12 Resveratrol protects against PM2.5-induced heart defects in zebrafish embryos as an antioxidant rather than as an AHR antagonist 期刊论文 Fei Ren;Yujie Huang;Yizhou Tao;Cheng Ji;Stanley Aniagu;Yan Jiang;Tao Chen
13 PM2.5 induces cardiac malformations via PI3K/akt2/mTORC1 signaling pathway in zebrafish larvae 期刊论文 Yan Jiang;Xiahao Zhao;Jin Chen;Stanley Aniagu;Tao CHen
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