南海产α-芋螺毒素环化及其药理学性质研究

81660585
2016
H3405.海洋药物
吴勇
地区科学基金项目
副教授
广西大学
37万元
稳定性;α-芋螺毒素;多肽合成;乙酰胆碱受体;环化
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Degradation kinetics of α-conotoxin TxID. 期刊论文 Xu Pan;Xiong Yang;Liu Yiqiao;Yu Shurun;Zhangsun Dongting;Wu Yong;Luo Sulan
2 Identification of Crucial Residues in alpha-Conotoxin EI Inhibiting Muscle Nicotinic Acetylcholine Receptor 期刊论文 Ning Jiong;Ren Jie;Xiong Yang;Wu Yong;Zhangsun Manqi;Zhangsun Dongting;Zhu Xiaopeng;Luo Sulan
3 Effect of Methionine Oxidation and Substitution of alpha-Conotoxin TxID on alpha 3 beta 4 Nicotinic Acetylcholine Receptor 期刊论文 Ren Jie;Li Rui;Ning Jiong;Zhu Xiaopeng;Zhangsun Dongting;Wu Yong;Luo Sulan
4 D-Amino Acid Substitution of alpha-Conotoxin RgIA Identifies its Critical Residues and Improves the Enzymatic Stability 期刊论文 Ren Jie;Zhu Xiaopeng;Xu Pan;Li Rui;Fu Ying;Dong Shuai;Zhangsun Dongting;Wu Yong;Luo Sulan
5 海洋芋螺资源图鉴 专著 石琼;高炳淼;彭超;吴勇
6 Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA. 期刊论文 Xu Pan;Kaas Quentin;Wu Yong;Zhu Xiaopeng;Li Xincan;Harvey Peta J;Zhangsun Dongting;Craik David J;Luo Sulan
7 Novel Mutant of α-conotoxin Peptide TxID 专利 罗素兰;长孙东亭;朱晓鹏;吴勇;于津鹏
8 Interaction of rat α9α10 nicotinic acetylcholine receptor with α-conotoxin RgIA and Vc1.1: Insights from docking, molecular dynamics and binding free energy contributions. 期刊论文 Li Rui;Li Xincan;Jiang Jiemei;Tian Yuanyuan;Liu Danrui;Zhangsun Donting;Fu Ying;Wu Yong;Luo Sulan
9 α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors 期刊论文 Yong Wu;Dongting Zhangsun;Xiaopeng Zhu;Quentin Kaas;Manqi Zhangsun;Peta J.Harvey;David J.Craik;J.Michael McIntosh;Sulan Luo
10 Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB. 期刊论文 Li Xincan;Wang Shuai;Zhu Xiaopeng;Zhangsun Dongting;Wu Yong;Luo Sulan
11 Alanine-Scanning Mutagenesis of α-Conotoxin GI Reveals the Residues Crucial for Activity at the Muscle Acetylcholine Receptor. 期刊论文 Ning Jiong;Li Rui;Ren Jie;Zhangsun Dongting;Zhu Xiaopeng;Wu Yong;Luo Sulan
12 Discovery Methodology of Novel Conotoxins from Conus Species. 期刊论文 Fu Ying;Li Cheng;Dong Shuai;Wu Yong;Zhangsun Dongting;Luo Sulan
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