人科动物特异基因USP6参与智力进化的分子机制研究
31871077
2018
C0906.认知神经生物学
王鑫
面上项目
教授
厦门大学
59万元
认知行为;学习;可塑性;离子通道;递质受体
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Overexpression of human SNX27 enhances learning and memory through modulating synaptic plasticity in mice | 期刊论文 | Huo Yuanhui;Gao Yue;Zheng Qiuyang;Zhao Dongdong;Guo Tiantian;Zhang Shuo;Zeng Yuzhe;Cheng Yiyun;Gu Huaping;Zhang Lishan;Zhu Bin;Luo Hong;Zhang Xian;Zhou Ying;Zhang Yun-Wu;Sun Hao;Xu Huaxi;Wang Xin |
| 2 | Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability | 期刊论文 | Zhang Haibin;Zheng Qiuyang;Guo Tiantian;Zhang Shijun;Zheng Shuang;Wang Ruimin;Deng Qingfang;Yang Guowei;Zhang Shuo;Tang Linxin;Qi Qiuping;Zhu Lin;Zhang Xiu-Fang;Luo Hong;Zhang Xian;Sun Hao;Gao Yue;Zhang Hongfeng;Zhou Ying;Han Aidong;Zhang Chen-Song;Xu Huaxi;Wang Xin |
| 3 | 治疗阿尔茨海默病的化合物 | 专利 | 王鑫;马磊;付建军;郑秋阳;周立成;邓青芳;时夕蒙;李桂林;王世华 |
| 4 | Novel KCNJ10 Compound Heterozygous Mutations Causing EAST/SeSAME-Like Syndrome Compromise Potassium Channel Function | 期刊论文 | Zhang Hongfeng;Zhu Lin;Wang Fengpeng;Wang Ruimin;Hong Yujuan;Chen Yangqin;Zhu Bin;Gao Yue;Luo Hong;Zhang Xian;Sun Hao;Zhou Ying;Yao Yi;Wang Xin |
| 5 | A de novo SCN8A heterozygous mutation in a child with epileptic encephalopathy: a case report | 期刊论文 | Lin Kao-Min;Su Geng;Wang Fengpeng;Zhang Xiaobin;Wang Yuanqing;Ren Jun;Wang Xin;Yao Yi;Zhou Ying |
| 6 | The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability | 期刊论文 | Zeng Fanwei;Ma Xuehai;Zhu Lin;Xu Qiang;Zeng Yuzhe;Gao Yue;Li Guilin;Guo Tiantian;Zhang Haibin;Tang Xiaoyan;Wang Ziqiang;Ye Zesen;Zheng Liangkai;Zhang Hongfeng;Zheng Qiuyang;Li Kunping;Lu Jinfang;Qi Xueting;Luo Hong;Zhang Xian;Wang Zhanxiang;Zhou Yulin;Yao Yi;Ke Rongqin;Zhou Ying;Liu Yan;Sun Hao;Huang Timothy;Shao Zhicheng;Xu Huaxi;Wang Xin |
| 7 | 戊酸衍生物在治疗唐氏综合征中的应用 | 专利 | 王鑫;张硕;郑秋阳;林志豪;王世华;周园园 |
| 8 | SNX14 deficiency-induced defective axonal mitochondrial transport in Purkinje cells underlies cerebellar ataxia and can be reversed by valproate | 期刊论文 | Zhang Hongfeng;Hong Yujuan;Yang Weijie;Wang Ruimin;Yao Ting;Wang Jian;Liu Ke;Yuan Huilong;Xu Chaoqun;Zhou Yuanyuan;Li Guanxian;Zhang Lishan;Luo Hong;Zhang Xian;Du Dan;Sun Hao;Zheng Qiuyang;Zhang Yun-Wu;Zhao Yingjun;Zhou Ying;Xu Huaxi;Wang Xin |
| 9 | 戊酸衍生物在治疗遗传性小脑共济失调中的应用 | 专利 | 王鑫;张洪峰;洪育娟;杨伟杰;王睿敏 |
| 10 | Trisomy 21-induced dysregulation of microglial homeostasis in Alzheimer's brains is mediated by USP25 | 期刊论文 | Zheng Qiuyang;Li Guilin;Wang Shihua;Zhou Ying;Liu Ke;Gao Yue;Zhou Yulin;Zheng Liangkai;Zhu Lin;Deng Qingfang;Wu Meiling;Di Anjie;Zhang Lishan;Zhao Yingjun;Zhang Hongfeng;Sun Hao;Dong Chen;Xu Huaxi;Wang Xin |
| 11 | USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation | 期刊论文 | Zheng Qiuyang;Song Beibei;Li Guilin;Cai Fang;Wu Meiling;Zhao Yingjun;Jiang Lulin;Guo Tiantian;Shen Mingyu;Hou Huan;Zhou Ying;Zhao Yini;Di Anjie;Zhang Lishan;Zeng Fanwei;Zhang Xiu-Fang;Luo Hong;Zhang Xian;Zhang Hongfeng;Zeng Zhiping;Huang Timothy Y;Dong Chen;Qing Hong;Zhang Yun;Zhang Qing;Wang Xu;Wu Yili;Xu Huaxi;Song Weihong;Wang Xin |
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