源于广西莪术的β-榄香烯的肝靶向抗肿瘤化合物的设计、合成与生物学评价

21262004
2012
B0706.药物化学生物学
王坚毅
地区科学基金项目
教授
广西大学
50万元
药物设计;杂环化合物;去唾液酸糖蛋白受体;肝靶向;β-榄香烯
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Mechanism of Mo-catalyzed C–S cleavage of thiophene 期刊论文 Liao, Chuanan|Wang, Jianyi|Li, Bin|
2 Synthesis and evaluation of a water-solubility glycosyl-rhodamine fluorescent probe detecting Hg2+ 期刊论文 Wang, Mian|Wang, Lisheng|Su, Guifa|Wang, Jianyi|
3 How the Bicyclo[4.1.0] Substrate Isomerizes into 4,5-Dihydrobenzo[b]furan: The Contribution from W(CO)(5) and NEt3 期刊论文 Wang, Mian|Wang, Lisheng|Wang, Jianyi|Jiang, Linbin|
4 铜(Ⅰ)催化硫代磷酸酯的烯丙基烷基化机理的理论研究 期刊论文 严志伟|盛文浩|王坚毅|
5 How rhodium (III) complexes catalyze alkenylation of C(sp(3))-H bond of 8-methyquinolines 期刊论文 Huang, Xueqiu|Wang, Mian|Wang, Lisheng|Wang, Jianyi|
6 Synthesis and characterization of glycosyl 1,2,3-triazole anticancer compounds with hepatic targeting potential 会议论文 王坚毅|陈政君|徐姣|杨晓骏|
7 Design and synthesis of glycosyl-1,3,4-thiadiaoles 会议论文 Shengying Huang|Xueqiu Huang|Xionghui Jiang|Jian Zhang|
8 The addition mechanism of TMSCN into N-acetylpyridinum to give 2-cyanoacetylpyridinum: The roles of TpW(NO)(PMe3) and DABCO 期刊论文 Wang, Jianyi|Cai, Dinglong|Zhang, Min|Wang, Mian|
9 The recognition mechanism of crizotinib on MTH1: influence of chirality on the bioactivity 期刊论文 Zhou Shuilian|Wang Mian|Tong Zhangfa|Wang Jianyi|
10 A Cooperative Mechanism of Clotrimazoles in P450 Revealed by the Dissociation Picture of Clotrimazole from P450 期刊论文 Wang, Mian|Baaden, Marc|Wang, Jianyi|Liang, Zhiqun|
11 Mechanism of Copper(I)-Catalyzed Allylic Alkylation of Phosphorothioate Esters: Influence of the Leaving Group on alpha Regioselectivity 期刊论文 Lein, Matthias|Jiang, Linbin|Wei, Wanxing|Wang, Jianyi|
12 What factors cause the complete substrate-controlled selectivity in Rh-2(Piv)(4)-catalyzed cycloadditions of 1,2,3-triazoles with isocyanates or isothiocyanates 期刊论文 Wang, Mian|Luo, Hao|Wang, Lisheng|Wang, Jianyi|
13 Copper-catalyzed diastereoselective aerobic intramolecular dehydrogenative coupling of hydrazones via sp(3) C-H functionalization 期刊论文 Zhang, Guangwu|Zhao, Yan|Wang, Jianyi|Ge, Haibo|
14 Synthesis and bio-evaluation of glycoyl-1,2,4-triazole 会议论文 Xionghui Jiang|Xueqiu Huang|Shengying Huang|Bubin Meng|
15 Why trans- or cis-Dimethyl Fumarate Addition to 2,5-Dimethylpyrrole Gives Exclusively trans-7-Azanorbornane 期刊论文 Wang, Mian|Luo, Hao|Zhang, Min|Wang, Jianyi|
16 克霉唑从P450酶解离的图像揭示多个克霉唑与P450酶协同作用的机理 会议论文 王勉|王坚毅|
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