立体电子效应调控的高灵敏双光子荧光探针设计及其在脑血管硝化应激损伤研究中的应用
21778048
2017
B0701.生物体系分子探针
李新
面上项目
副教授
浙江大学
60万元
脑卒中;荧光成像;双光子荧光探针;立体电子效应;过氧化亚硝酸阴离子
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Sequentially Activated Probe Design Strategy for Analyzing Metabolite Crosstalk in a Biochemical Cascade | 期刊论文 | Cheng Juan;Ren Yong;Huang Yujie;Li Xiaozhuan;Huang Mingzhu;Han Feng;Liang Xingguang;Li Xin |
| 2 | Bioinspired Design of Reversible Fluorescent Probes for Tracking Nitric Oxide Dynamics in Live Cells | 期刊论文 | Rui-Ying Guo;Yu-Tian Zhang;Supphachok Chanmungkalakul;Hao-Ran Guo;Yongzhou Hu;Jia Li;Xiaogang Liu;Yi Zang;Xin Li |
| 3 | 一种检测蛋白质巯基亚硝基化的荧光探针及其制备和应用 | 专利 | 李新;邵世怡;韩峰;卢应梅;胡永洲 |
| 4 | 含巯基荧光化合物或其硫酯衍生物及制备和应用 | 专利 | 李新;李佳;胡永洲;臧奕;郭瑞颖;张雨恬 |
| 5 | Bis-reaction-trigger as a strategy to improve the selectivity of fluorescent probes | 期刊论文 | Li Dan;Cheng Juan;Wang Cheng Kun;Ying Huazhou;Hu Yongzhou;Han Feng;Li Xin |
| 6 | Rational Design of the Benzothiazole-Based Fluorescent Scaffold for Tunable Emission | 期刊论文 | Yong Ren;Dong Fan;Huazhou Ying;Xin Li |
| 7 | Conformational restraint as a strategy for navigating towards lysosomes | 期刊论文 | Xing Guang Liang;Juan Cheng;Siyao Qin;Ling Xiao Shao;Ming Zhu Huang;Gang Wang;Yifeng Han;Feng Han;Xin Li |
| 8 | Microenvironment-Responsive Small-Molecule Probe for Pulmonary Fibrosis Detection | 期刊论文 | Dong Ying;Li Xiao-Rong;Chen Qi;Guo Rui-Ying;Tang Bi-Xi;Kan Wei-Juan;Zhang Wei;Hu Yongzhou;Li Jia;Zang Yi;Li Xin |
| 9 | 一种用于肺纤维化染色的荧光探针 | 专利 | 李新;李佳;胡永洲;臧奕;李晓荣;董莹 |
| 10 | Red-Shift (2-Hydroxyphenyl)-Benzothiazole Emission by Mimicking the Excited-State Intramolecular Proton Transfer Effect | 期刊论文 | Yong Ren;Lei Zhou;Xin Li |
| 11 | Physicochemical-property guided design of a highly sensitive probe to image nitrosative stress in the pathology of stroke | 期刊论文 | Cheng Juan;Li Dan;Sun Meiling;Wang Yi;Xu Qiao-Qin;Liang Xing-Guang;Lu Yun-Bi;Hu Yongzhou;Han Feng;Li Xin |
| 12 | Visualizing Autophagic Flux during Endothelial Injury with a Pathway-Inspired Tandem-Reaction Based Fluorogenic Probe | 期刊论文 | Lei Yu;Ren Wenming;Wang Cheng Kun;Tao Rong Rong;Xiang Huai Jiang;Feng Li Li;Gao Yin Ping;Jiang Quan;Li Xin;Hu Youhong;Han Feng |
| 13 | An inherently kidney-targeting near-infrared fluorophore based probe for early detection of acute kidney injury | 期刊论文 | Fangqin Wang;Xuefeng Jiang;Huaijiang Xiang;Ning Wang;Yunjing Zhang;Xi Yao;Ping Wang;Hao Pan;Lifang Yu;Yunfeng Cheng;Yongzhou Hu;Weiqiang Lin;Xin Li |
| 14 | A fluorogenic probe for tracking GSH flux in developing neurons | 期刊论文 | Haichao Zong;Jiayi Peng;Xiao-Rong Li;Meng Liu;Yongzhou Hu;Jia Li;Yi Zang;Xin Li;Tony D. James |
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